Search Results - "De michele, Elisa"
-
1
Risk factors for endocrine complications in transfusion-dependent thalassemia patients on chelation therapy with deferasirox: a risk assessment study from a multi-center nation-wide cohort
Published in Haematologica (Roma) (01-02-2022)“…Transfusion-dependent patients typically develop iron-induced cardiomyopathy, liver disease, and endocrine complications. We aimed to estimate the incidence of…”
Get full text
Journal Article -
2
Hearing loss in beta‐thalassaemia: An Italian multicentre case–control study
Published in British journal of haematology (01-05-2024)“…Summary Background Despite numerous studies, the true scenario of hearing loss in beta‐thalassaemia remains rather nebulous. Materials and methods Pure tone…”
Get full text
Journal Article -
3
Non-transfusion-dependent thalassemia in Italy: less blues, no role of reds
Published in Annals of hematology (2022)Get full text
Journal Article -
4
Auditory cortex hypoperfusion: a metabolic hallmark in Beta Thalassemia
Published in Orphanet journal of rare diseases (05-08-2021)“…Abstract Background Sensorineural hearing loss in beta-thalassemia is common and it is generally associated with iron chelation therapy. However, data are…”
Get full text
Journal Article -
5
Asymptomatic intracranial aneurysms in beta-thalassemia: a three-year follow-up report
Published in Orphanet journal of rare diseases (20-01-2020)“…No information is currently available regarding the natural history of asymptomatic intracranial aneurysms in beta-thalassemia, raising several concerns about…”
Get full text
Journal Article -
6
Brain iron content in systemic iron overload: A beta-thalassemia quantitative MRI study
Published in NeuroImage clinical (01-01-2019)“…•Iron overload is a life-threatening condition in beta-thalassemia.•Data on brain involvement in systemic iron overload are conflicting.•MRI quantification of…”
Get full text
Journal Article -
7
Endocrine function and bone disease during long‐term chelation therapy with deferasirox in patients with β‐thalassemia major
Published in American journal of hematology (01-12-2014)“…Iron overload in β‐thalassemia major (TM) typically results in iron‐induced cardiomyopathy, liver disease, and endocrine complications. We examined the…”
Get full text
Journal Article -
8
COVID 19 and Hemoglobinopathies: Update of the Italian Experience
Published in Blood (05-11-2020)“…Background. Patients with pre-existent chronic morbidities are likely to be more severely affected by SARS-Cov2 infection. In Italy, the “Società Italiana…”
Get full text
Journal Article -
9
Brain functional impairment in beta‐thalassaemia: the cognitive profile in Italian neurologically asymptomatic adult patients in comparison to the reported literature
Published in British journal of haematology (01-08-2019)“…Summary Cognitive involvement in beta‐thalassaemia is strikingly controversial and poorly studied in adulthood. This multicentre prospective study investigated…”
Get full text
Journal Article -
10
No evidence of increased cerebrovascular involvement in adult neurologically‐asymptomatic β‐Thalassaemia. A multicentre multimodal magnetic resonance study
Published in British journal of haematology (01-05-2019)“…Summary Multi‐factorial causes jeopardize brain integrity in β‐thalassaemia. Intracranial parenchymal and vascular changes have been reported among young…”
Get full text
Journal Article -
11
Long‐term improvement in cardiac magnetic resonance in β‐thalassemia major patients treated with deferasirox extends to patients with abnormal baseline cardiac function
Published in American journal of hematology (01-03-2019)“…The management of iron overload in thalassemia has changed dramatically since the implementation of magnetic resonance imaging, which allows detection of…”
Get full text
Journal Article -
12
No increased cerebrovascular involvement in adult beta-thalassemia by advanced MRI analyses
Published in Blood cells, molecules, & diseases (01-09-2019)“…Beta-thalassemia-related anemia and chronic hypercoagulative state are supposed to cause cumulative cerebrovascular damage with consequent parenchymal/vascular…”
Get full text
Journal Article -
13
Italian patients with hemoglobinopathies exhibit a 5‐fold increase in age‐standardized lethality due to SARS‐CoV‐2 infection
Published in American journal of hematology (01-02-2022)Get full text
Journal Article -
14
Thalassaemia is paradoxically associated with a reduced risk of in‐hospital complications and mortality in COVID‐19: Data from an international registry
Published in Journal of cellular and molecular medicine (01-05-2022)“…Although numerous patient‐specific co‐factors have been shown to be associated with worse outcomes in COVID‐19, the prognostic value of thalassaemic syndromes…”
Get full text
Journal Article -
15
White matter volume changes in adult beta‐thalassemia: Negligible and unrelated to anemia and cognitive performances
Published in American journal of hematology (01-06-2020)Get full text
Journal Article -
16
Diagnostic issues faced by a rare disease healthcare network during Covid-19 outbreak: data from the Campania Rare Disease Registry
Published in Journal of public health (Oxford, England) (13-05-2021)“…Abstract Background The aims of this study were: to investigate the capacity of the rare disease healthcare network in Campania to diagnose patients with rare…”
Get full text
Journal Article -
17
Headache in beta-thalassemia: An Italian multicenter clinical, conventional MRI and MR-angiography case-control study
Published in Blood cells, molecules, & diseases (01-03-2020)“…A strikingly increased headache prevalence was recently noted in Sri Lankan beta-thalassemia patients, raising several concerns regarding long-term…”
Get full text
Journal Article -
18
Cognitive, Brain and Intracranial Artery Involvement in Beta Thalassemia
Published in Blood (08-12-2017)“…Background: Brain involvement in beta thalassemia is scarcely known so far, and available data show different degrees of abnormalities in terms of…”
Get full text
Journal Article -
19
Long Term Efficacy Of Iron Chelation Therapy With Deferasirox On Endocrine Function In Thalassemia Major
Published in Blood (15-11-2013)“…Although the heart and liver have traditionally been the organs of interest for iron-related complications in Thalassemia Major (TM), endocrine disorders are…”
Get full text
Journal Article -
20
Endocrine function and bone disease during long-term chelation therapy with deferasirox in patients with [beta]-thalassemia major
Published in American journal of hematology (01-12-2014)“…Iron overload in [beta]-thalassemia major (TM) typically results in iron-induced cardiomyopathy, liver disease, and endocrine complications. We examined the…”
Get full text
Journal Article