Search Results - "De la Motte Rouge, Thibault"

Survival Impact of Locoregional Treatment of the Primary Tumor in De Novo Metastatic Breast Cancers in a Large Multicentric Cohort Study: A Propensity Score-Matched Analysis by Pons-Tostivint, Elvire, Kirova, Youlia, Lusque, Amélie, Campone, Mario, Geffrelot, Julien, Mazouni, Chafika, Mailliez, Audrey, Pasquier, David, Madranges, Nicolas, Firmin, Nelly, Crouzet, Agathe, Gonçalves, Anthony, Jankowski, Clémentine, De La Motte Rouge, Thibault, Pouget, Nicolas, de La Lande, Brigitte, Mouttet-Boizat, Delphine, Ferrero, Jean-Marc, Uwer, Lionel, Eymard, Jean-Christophe, Mouret-Reynier, Marie-Ange, Petit, Thierry, Robain, Mathieu, Filleron, Thomas, Cailliot, Christian, Dalenc, Florence

“…Introduction Improvement in overall survival (OS) by locoregional treatment (LRT) of the primary tumor in de novo metastatic breast cancer (MBC) patients…”
Get full text

Development of multiplex digital PCR assays for the detection of PIK3CA mutations in the plasma of metastatic breast cancer patients by Corné, Julien, Le Du, Fanny, Quillien, Véronique, Godey, Florence, Robert, Lucie, Bourien, Héloïse, Brunot, Angélique, Crouzet, Laurence, Perrin, Christophe, Lefeuvre-Plesse, Claudia, Diéras, Véronique, De la Motte Rouge, Thibault

“…With the approval of new therapies targeting the PI3K pathway, the detection of PIK3CA mutations has become a key factor in treatment management for HR+/HER2−…”
Get full text

Methods for the assessment of mitochondrial membrane permeabilization in apoptosis by Galluzzi, Lorenzo, Zamzami, Naoufal, de La Motte Rouge, Thibault, Lemaire, Christophe, Brenner, Catherine, Kroemer, Guido

“…Mitochondrial membrane permeabilization (MMP) is considered as the “point-of-no-return” in numerous models of programmed cell death. Indeed, mitochondria…”
Get full text

Prognostic Impact of Vitamin B6 Metabolism in Lung Cancer by Galluzzi, Lorenzo, Vitale, Ilio, Senovilla, Laura, Olaussen, Ken André, Pinna, Guillaume, Eisenberg, Tobias, Goubar, Aïcha, Martins, Isabelle, Michels, Judith, Kratassiouk, Gueorgui, Carmona-Gutierrez, Didac, Scoazec, Marie, Vacchelli, Erika, Schlemmer, Frederic, Kepp, Oliver, Shen, Shensi, Tailler, Maximilien, Niso-Santano, Mireia, Morselli, Eugenia, Criollo, Alfredo, Adjemian, Sandy, Jemaà, Mohamed, Chaba, Kariman, Pailleret, Claire, Michaud, Mickaël, Pietrocola, Federico, Tajeddine, Nicolas, de La Motte Rouge, Thibault, Araujo, Natalia, Morozova, Nadya, Robert, Thomas, Ripoche, Hugues, Commo, Frederic, Besse, Benjamin, Validire, Pierre, Fouret, Pierre, Robin, Angélique, Dorvault, Nicolas, Girard, Philippe, Gouy, Sébastien, Pautier, Patricia, Jägemann, Nora, Nickel, Ann-Christin, Marsili, Sabrina, Paccard, Caroline, Servant, Nicolas, Hupé, Philippe, Behrens, Carmen, Behnam-Motlagh, Parviz, Kohno, Kimitoshi, Cremer, Isabelle, Damotte, Diane, Alifano, Marco, Midttun, Øivind, Ueland, Per Magne, Lazar, Vladimir, Dessen, Philippe, Zischka, Hans, Chatelut, Etienne, Castedo, Maria, Madeo, Frank, Barillot, Emmanuel, Thomale, Juergen, Wistuba, Ignacio Ivan, Sautès-Fridman, Catherine, Zitvogel, Laurence, Soria, Jean-Charles, Harel-Bellan, Annick, Kroemer, Guido

“…Patients with non-small cell lung cancer (NSCLC) are routinely treated with cytotoxic agents such as cisplatin. Through a genome-wide siRNA-based screen, we…”
Get full text

Clinical Response of Carcinomas Harboring the BRD4-NUT Oncoprotein to the Targeted Bromodomain Inhibitor OTX015/MK-8628 by Stathis, Anastasios, Zucca, Emanuele, Bekradda, Mohamed, Gomez-Roca, Carlos, Delord, Jean-Pierre, de La Motte Rouge, Thibault, Uro-Coste, Emmanuelle, de Braud, Filippo, Pelosi, Giuseppe, French, Christopher A

“…The antineoplastic, prodifferentiative effects of bromodomain and extra-terminal (BET) bromodomain (BRD) inhibitors were initially discovered in NUT midline…”
Get more information

How and when to refer patients for oncogenetic counseling in the era of PARP inhibitors by Neviere, Zoé, De La Motte Rouge, Thibault, Floquet, Anne, Johnson, Alison, Berthet, Pascaline, Joly, Florence

“…Poly(ADP-ribose)polymerase (PARP) inhibitors are targeted therapy for cancers with homologous repair deficiency (HRD). They were first approved for ovarian…”
Get full text

Cabazitaxel Remains Active in Patients Progressing After Docetaxel Followed by Novel Androgen Receptor Pathway Targeted Therapies by Al Nakouzi, Nader, Le Moulec, Sylvestre, Albigès, Laurence, Wang, Chris, Beuzeboc, Philippe, Gross-Goupil, Marine, de La Motte Rouge, Thibault, Guillot, Aline, Gajda, Dorota, Massard, Christophe, Gleave, Martin, Fizazi, Karim, Loriot, Yohann

“…Abstract Background Cabazitaxel, abiraterone acetate (AA), and enzalutamide have been approved for the treatment of patients with metastatic…”
Get full text

Gynecologic Cancer Intergroup (GCIG) consensus review for ovarian germ cell tumors by Brown, Jubilee, Friedlander, Michael, Backes, Floor J, Harter, Philipp, O'Connor, Dennis M, de la Motte Rouge, Thibault, Lorusso, Domenica, Maenpaa, Johanne, Kim, Jae-Weon, Tenney, Meghan E, Seckl, Michael J

“…Most women diagnosed with malignant ovarian germ cell tumors have curable disease and experience excellent survival with manageable treatment-associated…”
Get more information

Survival outcomes of metastatic breast cancer patients by germline BRCA1/2 status in a large multicenter real‐world database by Mailliez, Audrey, D'Hondt, Veronique, Lusque, Amelie, Caron, Olivier, Cabel, Luc, Goncalves, Anthony, Debled, Marc, Gladieff, Laurence, Ferrero, Jean‐Marc, Petit, Thierry, Mouret‐Reynier, Marie Ange, Eymard, Jean‐Christophe, Levy, Christelle, Uwer, Lionel, Leheurteur, Marianne, Desmoulins, Isabelle, Bachelot, Thomas, Frenel, Jean‐Sebastien, Motte Rouge, Thibault, Simon, Gaëtane, Jacot, William, Delaloge, Suzette

“…The outcomes and best treatment strategies for germline BRCA1/2 mutation (gBRCAm) carriers with metastatic breast cancer (MBC) remain uncertain. We compared…”
Get full text

Prognostic Impact of Vitamin B6 Metabolism in Lung Cancer by Galluzzi, Lorenzo, Vitale, Ilio, Senovilla, Laura, Olaussen, Ken André, Pinna, Guillaume, Eisenberg, Tobias, Goubar, Aïcha, Martins, Isabelle, Michels, Judith, Kratassiouk, Gueorgui, Carmona-Gutierrez, Didac, Scoazec, Marie, Vacchelli, Erika, Schlemmer, Frederic, Kepp, Oliver, Shen, Shensi, Tailler, Maximilien, Niso-Santano, Mireia, Morselli, Eugenia, Criollo, Alfredo, Adjemian, Sandy, Jemaà, Mohamed, Chaba, Kariman, Pailleret, Claire, Michaud, Mickaël, Pietrocola, Federico, Tajeddine, Nicolas, de La Motte Rouge, Thibault, Araujo, Natalia, Morozova, Nadya, Robert, Thomas, Ripoche, Hugues, Commo, Frederic, Besse, Benjamin, Validire, Pierre, Fouret, Pierre, Robin, Angélique, Dorvault, Nicolas, Girard, Philippe, Gouy, Sébastien, Pautier, Patricia, Jägemann, Nora, Nickel, Ann-Christin, Marsili, Sabrina, Paccard, Caroline, Servant, Nicolas, Hupé, Philippe, Behrens, Carmen, Behnam-Motlagh, Parviz, Kohno, Kimitoshi, Cremer, Isabelle, Damotte, Diane, Alifano, Marco, Midttun, Øivind, Ueland, Per Magne, Lazar, Vladimir, Dessen, Philippe, Zischka, Hans, Chatelut, Etienne, Castedo, Maria, Madeo, Frank, Barillot, Emmanuel, Thomale, Juergen, Wistuba, Ignacio Ivan, Sautès-Fridman, Catherine, Zitvogel, Laurence, Soria, Jean-Charles, Harel-Bellan, Annick, Kroemer, Guido

Get full text

Efficacy of chemotherapy according to BRCA status in patients with high-grade serous ovarian carcinoma at first platinum-sensitive relapse by Brouillard-Saby, Flora, Saint-Martin, Caroline, Ray-Coquard, Isabelle, Gladieff, Laurence, Pomel, Christophe, Colombo, Pierre-Emmanuel, Classe, Jean-Marc, Chevrier, Marion, Joly, Florence, De la Motte Rouge, Thibault, Floquet, Anne, Sabatier, Renaud, Barranger, Emmanuel, Costaz, Hélène, Leblanc, Eric, Marchal, Frédéric, Pautier, Patricia, Bosquet, Lise, Rodrigues, Manuel

“…Chemotherapy for high-grade serous ovarian cancers in platinum-sensitive relapse includes carboplatin/paclitaxel, carboplatin/gemcitabine, and…”
Get more information

Outcomes after adjuvant chemotherapy in the treatment of high‐risk urothelial carcinoma of the upper urinary tract (UUT‐UC) by Vassilakopoulou, Maria, de la Motte Rouge, Thibault, Colin, Pierre, Ouzzane, Adil, Khayat, David, Dimopoulos, Meletios‐Athanasios, Papadimitriou, Christos A., Bamias, Aristotle, Pignot, Géraldine, Nouhaud, François Xavier, Hurel, Sophie, Guy, Laurent, Bigot, Pierre, Roumiguié, Mathieu, Rouprêt, Morgan

“…BACKGROUND: Urothelial carcinoma of the upper urinary tract (UUT‐UC) was a rare, aggressive urologic cancer with a propensity for multifocality, local…”
Get full text

Efficacy of taxanes rechallenge in first-line treatment of early metastatic relapse of patients with HER2-negative breast cancer previously treated with a (neo)adjuvant taxanes regimen: A multicentre retrospective observational study by Vasseur, Antoine, Carton, Matthieu, Guiu, Severine, Augereau, Paule, Uwer, Lionel, Mouret-Reynier, Marie-Ange, Levy, Christelle, Eymard, Jean-Christophe, Ferrero, Jean-Marc, Leheurteur, Marianne, Goncalves, Anthony, Robert, Marie, De La Motte Rouge, Thibault, Bachelot, Thomas, Petit, Thierry, Debled, Marc, Grinda, Thomas, Desmoulins, Isabelle, Vanlemmens, Laurence, Nicolaï, Vincent, Simon, Gaëtane, Cabel, Luc

“…Taxanes are one of the most effective chemotherapies (CT) in breast cancer (BC), but the efficacy of taxanes rechallenge in early metastatic relapse has been…”
Get full text

Knowledge of bladder cancer in the French population: results of the EDIFICE 6 survey by Rouprêt, Morgan, Morère, Jean‐François, Touboul, Chantal, Lhomel, Christine, Couraud, Sébastien, Motte Rouge, Thibault

“…Objective To assess awareness of bladder cancer (BCa) in France. Methods The French nationwide observational survey EDIFICE 6 was conducted online (26 June–28…”
Get full text

The Landscape and Therapeutic Implications of Molecular Profiles in Epithelial Ovarian Cancer by Dion, Ludivine, Carton, Isis, Jaillard, Sylvie, Nyangoh Timoh, Krystel, Henno, Sébastien, Sardain, Hugo, Foucher, Fabrice, Levêque, Jean, de la Motte Rouge, Thibault, Brousse, Susie, Lavoué, Vincent

“…Epithelial ovarian cancer (EOC) affects 43,000 women worldwide every year and has a five-year survival rate of 30%. Mainstay treatment is extensive surgery and…”
Get full text

Outcome beyond third-line chemotherapy for metastatic triple-negative breast cancer in the French ESME program by Cabel, Luc, Carton, Matthieu, Pistilli, Barbara, Dalenc, Florence, Vanlemnens, Laurence, Levy, Christelle, Jacot, William, Debled, Michel, Loeb, Agnes, Hennequin, Audrey, De la Motte Rouge, Thibault, Laborde, Lilian, Laurent, Carine, Chamorey, E., Parent, Damien, Petit, Thierry, Mouret-Reynier, Marie-Ange, Campone, Mario, Perrocheau, Geneviève, Labreveux, Claire, Bachelot, Thomas, Robain, Mathieu, Lerebours, Florence

“…Among metastatic breast cancer (MBC) patients, those with a triple-negative breast cancer phenotype (mTNBC) have the worst prognosis, but the benefit of…”
Get full text

Real-World Data on Newly Diagnosed BRCA-Mutated High-Grade Epithelial Ovarian Cancers: The French National Multicenter ESME Database by Bini, Marta, Quesada, Stanislas, Meeus, Pierre, Rodrigues, Manuel, Leblanc, Eric, Floquet, Anne, Pautier, Patricia, Marchal, Frédéric, Provansal, Magali, Campion, Loïc, Causeret, Sylvain, Gourgou, Sophie, Ray-Coquard, Isabelle, Classe, Jean-Marc, Pomel, Christophe, De La Motte Rouge, Thibault, Barranger, Emmanuel, Savoye, Aude Marie, Guillemet, Cécile, Gladieff, Laurence, Demarchi, Martin, Rouzier, Roman, Courtinard, C, Romeo, Clémence, Joly, Florence

“…Background: In spite of the frequency and clinical impact of BRCA1/2 alterations in high-grade epithelial ovarian cancer (HGEOC), real-world information based…”
Get full text

A novel epidermal growth factor receptor inhibitor promotes apoptosis in non-small cell lung cancer cells resistant to erlotinib by DE LA MOTTE ROUGE, Thibault, GALLUZZI, Lorenzo, PIERRON, Gerard, PINNA, Guillaume, ARAUJO, Natalia, HAREL-BELAN, Annick, ARMAND, Jean-Pierre, TAI WAI WONG, SORIA, Jean Charles, KROEMER, Guido, OLAUSSEN, Ken A, ZERMATI, Yael, TASDEMIR, Ezgi, ROBERT, Thomas, RIPOCHE, Hugues, LAZAR, Vladimir, DESSEN, Philippe, HARPER, Francis

“…Non-small cell lung cancer (NSCLC) with activating mutations in the epidermal growth factor receptor (EGFR) responds to EGFR tyrosine kinase inhibitors such as…”
Get full text

Real-world evidence of the management and prognosis of young women (⩽40 years) with de novo metastatic breast cancer by Mallet, Amélie, Lusque, Amélie, Levy, Christelle, Pistilli, Barbara, Brain, Etienne, Pasquier, David, Debled, Marc, Thery, Jean Christophe, Gonçalves, Anthony, Desmoulins, Isabelle, De La Motte Rouge, Thibault, Faure, Christelle, Ferrero, Jean Marc, Eymard, Jean Christophe, Mouret-Reynier, Marie Ange, Patsouris, Anne, Cottu, Paul, Dalenc, Florence, Petit, Thierry, Payen, Olivier, Uwer, Lionel, Guiu, Séverine, Frenel, Jean Sébastien

“…Background: Breast cancer (BC) in young women merits a specific approach given the associated fertility, genetic and psychosocial issues. De novo metastatic…”
Get full text

From Targeting Somatic Mutations to Finding Inherited Cancer Predispositions: The Other Side of the Coin by Pujol, Pascal, De La Motte Rouge, Thibault, Penault-Llorca, Frédérique

“…The expanding use of tumor genome analysis by next generation sequencing to drive target therapies has led to increased germline findings in genes predisposing…”
Get full text