Search Results - "De Wolf, K."

In vivo tumor transfection mediated by polyplexes based on biodegradable poly(DMAEA)-phosphazene by de Wolf, Holger K., Luten, Jordy, Snel, Cor J., Oussoren, Christien, Hennink, Wim E., Storm, Gert

“…In recent years, increasing interest is being paid to the design of transfectants based on non-toxic and biodegradable polymers for gene therapy purposes. We…”
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Biodegradable poly(2-dimethylamino ethylamino)phosphazene for in vivo gene delivery to tumor cells. Effect of polymer molecular weight by de Wolf, Holger K, de Raad, Markus, Snel, Cor, van Steenbergen, Mies J, Fens, Marcel H A M, Storm, Gert, Hennink, Wim E

“…Previously, we have shown that complexes of plasmid DNA with the biodegradable polymer poly(2-dimethylamino ethylamino)phosphazene (p(DMAEA)-ppz) mediated…”
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DNA identification of species of the Anopheles maculipennis complex and first record of An. daciae in Belgium by Smitz, N., De Wolf, K., Gheysen, A., Deblauwe, I., Vanslembrouck, A., Meganck, K., De Witte, J., Schneider, A., Verlé, I., Dekoninck, W., Gombeer, S., Vanderheyden, A., De Meyer, M., Backeljau, T., Müller, R., Van Bortel, W.

“…The present study aimed at identifying the members of the Anopheles maculipennis complex (Diptera: Culicidae) occurring in Belgium. Therefore, the second…”
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SP-0520: The promises of dose painting by De Neve, W, Veldeman, L, Ost, P, Duprez, F, Vandecasteele, K, De Wolf, K, Monten, C, Berwouts, D, Olteanu, A.M.L, Vercauteren, T, De Gersem, W

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Plasmid CpG Depletion Improves Degree and Duration of Tumor Gene Expression After Intravenous Administration of Polyplexes by de Wolf, Holger K., Johansson, Nina, Thong, Anh-Thy, Snel, Cor J., Mastrobattista, Enrico, Hennink, Wim E., Storm, Gert

“…Purpose Tumor gene expression after the intravenous (i.v.) administration of current polymer-based gene delivery systems is generally low and short-lived…”
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OC-0055: Biological image guided stereotactic radiosurgery for painful bone metastasis: a randomized phase II trial by De Wolf, K, Berwouts, D, Lambert, B, Bultijnck, R, De Neve, W, De Lobel, L, Speleers, B, Olteanu, L, Madani, I, Ost, P

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Unlocking the wealth of Dutch pollen data for future research and education by de Wolf, Iris K., Donders, Timme H., Hoek, Wim Z., Gouw-Bouman, Marjolein T.I.J., Giesecke, Thomas

“…Nearly 100 years ago, scientists started analysing fossil pollen and spores in the Netherlands. Since then, an enormous number of fossil pollen datasets have…”
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Comparison of a new procalcitonin assay from roche with the established method on the brahms kryptor by de Wolf, Holger K, Gunnewiek, Jacqueline Klein, Berk, Yvonne, van den Ouweland, Jody, de Metz, Menno

“…[...] the new PCT assay on the Roche Modular shows a good correlation and concordance with the PCT assay on the Brahms Kryptor in a highly relevant patient…”
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Impact of interactions between drugs and laboratory test results on diagnostic test interpretation - a systematic review by van Balveren, Jasmijn A, Verboeket-van de Venne, Wilhelmine P H G, Erdem-Eraslan, Lale, de Graaf, Albert J, Loot, Annemarieke E, Musson, Ruben E A, Oosterhuis, Wytze P, Schuijt, Martin P, van der Sijs, Heleen, Verheul, Rolf J, de Wolf, Holger K, Kusters, Ron, Hoedemakers, Rein M J

“…Intake of drugs may influence the interpretation of laboratory test results. Knowledge and correct interpretation of possible drug-laboratory test interactions…”
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A novel C2 transferrin variant interfering with the analysis of carbohydrate-deficient transferrin by de Wolf, Holger K., Huijben, Karin, van Wijnen, Merel, de Metz, Menno, Wielders, Jos P.M.

“…Carbohydrate-deficient transferrin (CDT) is used as a marker for chronic alcohol abuse. The presence of genetic transferrin variants might affect an…”
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A particular subtype of ichthyosis congenita type III. Clinical, light, and electron microscopic features by de Wolf, K, Gourdain, J M, Dobbeleer, G D, Song, M

“…We report the case of a second patient with the extraordinary ultrastructural findings of vacuolated structures intermingled with membranes in the perinuclear…”
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Diagnostic error as a result of drug-laboratory test interactions by van Balveren, Jasmijn A, Verboeket-van de Venne, Wilhelmine P H G, Erdem-Eraslan, Lale, de Graaf, Albert J, Loot, Annemarieke E, Musson, Ruben E A, Oosterhuis, Wytze P, Schuijt, Martin P, van der Sijs, Heleen, Verheul, Rolf J, de Wolf, Holger K, Kusters, Ron, Hoedemakers, Rein M J

“…Background Knowledge of possible drug-laboratory test interactions (DLTIs) is important for the interpretation of laboratory test results. Test results may be…”
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Biodegradable, Cationic Methacrylamide-Based Polymers for Gene Delivery to Ovarian Cancer Cells in Mice by de Wolf, Holger K, Luten, Jordy, Snel, Cor J, Storm, Gert, Hennink, Wim E

“…A series of cationic, methacrylamide polymers was tested for use as a biodegradable gene carrier in ovarian cancer. Tumor transfection activity of polyplexes…”
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Effect of cationic carriers on the pharmacokinetics and tumor localization of nucleic acids after intravenous administration by de Wolf, Holger K., Snel, Cor J., Verbaan, Ferry J., Schiffelers, Raymond M., Hennink, Wim E., Storm, Gert

“…Nucleic acid based therapeutics are currently being studied for their application in cancer therapy. In this study, the effect of different cationic delivery…”
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Synthetic delivery systems for intravenous administration of nucleic acids by Schiffelers, Raymond M, de Wolf, Holger K, van Rooy, Inge, Storm, Gert

“…At present, there are no intravenously administered nucleic acid-based therapeutics that have been approved for human use. This reflects the difficulties in…”
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OC-0017: Combined High Dose Radiation and Ipilimumab in Metastatic Melanoma, a Phase I Dose Escalation Trial by De Wolf, K., Kruse, V., Brochez, L., Sundahl, N., Van Gele, M., Speeckaert, R., Ost, P.

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Characterising Dutch forests, wetlands and cultivated lands on the basis of phytolith assemblages by de Wolf, Iris K., McMichael, Crystal N.H., Philip, Annemarie L., Gosling, William D.

“…Palaeoecological reconstructions in the Netherlands are commonly based on pollen and macrofossil analysis, but can be limited if the preservation of organic…”
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Phase I trial of stereotactic body radiotherapy with concurrent fixed dose ipilimumab in metastatic melanoma: Dose limiting toxicity and abscopal effect by De Wolf, K., Ost, P., Kruse, V., Brochez, L., Chevolet, I.

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PV-0550: Combined high dose radiation and tyrosine kinase inhibitors in renal cell carcinoma: a phase I trial by De Wolf, K., Rottey, S., Vermaelen, K., Decaestecker, K., Sundahl, N., De Meerleer, G., Lumen, N., Fonteyne, V., De Maeseneer, D., Ost, P.

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Dermatologic and systemic manifestations of syphilis by Goens, J L, Janniger, C K, De Wolf, K

“…The incidence of syphilis is increasing, predominantly among urban heterosexuals. Early recognition is important in preventing progression of the disease and…”
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