Search Results - "De Witte, Witte"

Immunomodulation By Therapeutic Mesenchymal Stromal Cells (MSC) Is Triggered Through Phagocytosis of MSC By Monocytic Cells by de Witte, Samantha F.H., Luk, Franka, Sierra Parraga, Jesus M., Gargesha, Madhu, Merino, Ana, Korevaar, Sander S., Shankar, Anusha S., O'Flynn, Lisa, Elliman, Steve J., Roy, Debashish, Betjes, Michiel G.H., Newsome, Philip N., Baan, Carla C., Hoogduijn, Martin J.

“…Mesenchymal stem or stromal cells (MSC) are under investigation as a potential immunotherapy. MSC are usually administered via intravenous infusion, after…”
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Evaluation of 14 organic solvents and carriers for screening applications in zebrafish embryos and larvae by Maes, Jan, Verlooy, Lien, Buenafe, Olivia E, de Witte, Peter A M, Esguerra, Camila V, Crawford, Alexander D

“…Zebrafish are rapidly growing in popularity as an in vivo model system for chemical genetics, drug discovery, and toxicology, and more recently also for…”
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Microglia-mediated synaptic pruning as a key deficit in neurodevelopmental disorders: Hype or hope? by Mordelt, Annika, de Witte, Lot D.

“…There is a consensus in the field that microglia play a prominent role in neurodevelopmental processes like synaptic pruning and neuronal network maturation…”
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Validation of the zebrafish pentylenetetrazol seizure model: locomotor versus electrographic responses to antiepileptic drugs by Afrikanova, Tatiana, Serruys, Ann-Sophie K, Buenafe, Olivia E M, Clinckers, Ralph, Smolders, Ilse, de Witte, Peter A M, Crawford, Alexander D, Esguerra, Camila V

“…Zebrafish have recently emerged as an attractive in vivo model for epilepsy. Seven-day-old zebrafish larvae exposed to the GABA(A) antagonist pentylenetetrazol…”
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Burnout Assessment Tool (BAT)-Development, Validity, and Reliability by Schaufeli, Wilmar B, Desart, Steffie, De Witte, Hans

“…This paper introduces a new definition for burnout and investigates the psychometric properties of the Burnout Assessment Tool (BAT). In a prior qualitative…”
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Pharmacological characterization of an antisense knockdown zebrafish model of Dravet syndrome: inhibition of epileptic seizures by the serotonin agonist fenfluramine by Zhang, Yifan, Kecskés, Angéla, Copmans, Daniëlle, Langlois, Mélanie, Crawford, Alexander D, Ceulemans, Berten, Lagae, Lieven, de Witte, Peter A M, Esguerra, Camila V

“…Dravet syndrome (DS) is one of the most pharmacoresistant and devastating forms of childhood epilepsy syndromes. Distinct de novo mutations in the SCN1A gene…”
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Combining Biofeedback with Stress Management Interventions: A Systematic Review of Physiological and Psychological Effects by De Witte, Nele A. J., Buyck, Inez, Van Daele, Tom

“…Current mental healthcare systems experience difficulties meeting the challenges of a growing population with elevated stress symptoms. Outpatient stress…”
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RICOPILI: Rapid Imputation for COnsortias PIpeLIne by Lam, Max, Awasthi, Swapnil, Watson, Hunna J, Goldstein, Jackie, Panagiotaropoulou, Georgia, Trubetskoy, Vassily, Karlsson, Robert, Frei, Oleksander, Fan, Chun-Chieh, De Witte, Ward, Mota, Nina R, Mullins, Niamh, Brügger, Kim, Lee, S Hong, Wray, Naomi R, Skarabis, Nora, Huang, Hailiang, Neale, Benjamin, Daly, Mark J, Mattheisen, Manuel, Walters, Raymond, Ripke, Stephan

“…Abstract Summary Genome-wide association study (GWAS) analyses, at sufficient sample sizes and power, have successfully revealed biological insights for…”
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Helpful or Harmful? The Role of Personality Traits in Student Experiences of the COVID-19 Crisis and School Closure by Iterbeke, Kaat, De Witte, Kristof

“…Little is known about the individual differences in student experiences and expectations of the COVID-19 crisis and the resulting school closures. Yet, as the…”
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An Emerging Role for Sigma-1 Receptors in the Treatment of Developmental and Epileptic Encephalopathies by Martin, Parthena, Reeder, Thadd, Sourbron, Jo, de Witte, Peter A M, Gammaitoni, Arnold R, Galer, Bradley S

“…Developmental and epileptic encephalopathies (DEEs) are complex conditions characterized primarily by seizures associated with neurodevelopmental and motor…”
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A Rasch analysis of the Burnout Assessment Tool (BAT) by Hadžibajramović, Emina, Schaufeli, Wilmar, De Witte, Hans

“…Burnout as a concept indicative of a work-related state of mental exhaustion is recognized around the globe. Numerous studies showed that burnout has negative…”
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Predicting ADL disability in community-dwelling elderly people using physical frailty indicators: a systematic review by Vermeulen, Joan, Neyens, Jacques C L, van Rossum, Erik, Spreeuwenberg, Marieke D, de Witte, Luc P

“…Disability in Activities of Daily Living (ADL) is an adverse outcome of frailty that places a burden on frail elderly people, care providers and the care…”
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The Impact of School Closures on Learning and Mental Health of Children: Lessons From the COVID-19 Pandemic by Mazrekaj, Deni, De Witte, Kristof

“…To curb the spread of the coronavirus, almost all countries implemented nationwide school closures. Suddenly, students experienced a serious disruption to…”
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Fenfluramine acts as a positive modulator of sigma-1 receptors by Martin, Parthena, de Witte, Peter A.M., Maurice, Tangui, Gammaitoni, Arnold, Farfel, Gail, Galer, Bradley

“…Adjunctive fenfluramine hydrochloride, classically described as acting pharmacologically through a serotonergic mechanism, has demonstrated a unique and robust…”
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Quality assessment of the blue mussel (Mytilus edulis): Comparison between commercial and wild types by De Witte, B., Devriese, L., Bekaert, K., Hoffman, S., Vandermeersch, G., Cooreman, K., Robbens, J.

“…•Multidisciplinary comparison of consumption and wild types mussels.•Microplastic determination including introduction of the concept limit of…”
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In vivo Target Residence Time and Kinetic Selectivity: The Association Rate Constant as Determinant by de Witte, Wilhelmus E.A, Danhof, Meindert, van der Graaf, Piet H, de Lange, Elizabeth C.M

“…It is generally accepted that, in conjunction with pharmacokinetics, the first-order rate constant of target dissociation is a major determinant of the time…”
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Getting to the Heart of Emotion Regulation in Youth: The Role of Interoceptive Sensitivity, Heart Rate Variability, and Parental Psychopathology by De Witte, Nele A J, Sütterlin, Stefan, Braet, Caroline, Mueller, Sven C

“…Emotion regulation and associated autonomic activation develop throughout childhood and adolescence under the influence of the family environment…”
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The implications of target saturation for the use of drug–target residence time by de Witte, Wilhelmus E. A., Danhof, Meindert, van der Graaf, Piet H., de Lange, Elizabeth C. M.

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Understanding the care and support needs of older people: a scoping review and categorisation using the WHO international classification of functioning, disability and health framework (ICF) by Abdi, Sarah, Spann, Alice, Borilovic, Jacinta, de Witte, Luc, Hawley, Mark

“…The number of older people with unmet care and support needs is increasing substantially due to the challenges facing the formal and informal care system in…”
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Using Zebrafish as a Disease Model to Study Fibrotic Disease by Wang, Xixin, Copmans, Daniëlle, de Witte, Peter A. M.

“…In drug discovery, often animal models are used that mimic human diseases as closely as possible. These animal models can be used to address various scientific…”
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