Search Results - "De Witte, Ph"

Alcohol and withdrawal: from animal research to clinical issues by De Witte, Ph, Pinto, E., Ansseau, M., Verbanck, P.

“…The withdrawal syndrome in alcohol-dependent patients appears to be a major stressful event whose intensity increases with repetition of detoxifications…”
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Taurine concentration in the brain and in the plasma following intraperitoneal injections by Lallemand, F, De Witte, Ph

“…The effect of different taurine doses (0.050, 0.125, 0.250, 0.500 and 1.000 g/kg) administered intraperitoneally to Wistar rats was studied in both the plasma…”
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Effects of CB1 Cannabinoid Receptor Blockade on Ethanol Preference After Chronic Ethanol Administration by Lallemand, F., Soubrié, P. H., de Witte, P. H.

“…Background: Chronic ethanol administration results in neurobiological alterations similar to those observed after chronic cannabinoid exposure. The purpose of…”
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Compensatory effects of palatable and non-palatable substances on the ethanol consumption in a free-choice procedure in rats by De Witte, P, Michiels, M

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L-NNA Decreases Cortical Vascularization, Alcohol Preference and Withdrawal in Alcoholic Rats by Lallemand, F, De Witte, Ph

“…Rats, which were made chronically alcoholic in combination with L-N ο-nitro-arginine (L-NNA) treatment (5 mg/kg/day), a nitric oxide (NO) synthase inhibitor,…”
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Increase in neuro-inhibitory amino-acids during alcoholization and in neuro-excitatory amino-acids during withdrawal by De Witte, Ph, Dahchour, A.

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Changes in plasma taurine levels after different endurance events by Ward, R.J, Francaux, M, Cuisinier, C, Sturbois, X, Witte, D

“…The sulphonated amino acid taurine increased significantly in the plasma of trained athletes after three endurance exercises of different duration and…”
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Adrenalectomy prevents the development of alcohol preference in male rats by Lamblin, F., De Witte, Ph

“…By forcing adrenalectomized (ADX) and sham-operated (SHAM) rats to chronically drink ethanol by mean of presentation of only one drinking bottle containing 10%…”
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Neurotensin and cholecystokinin microinjected into the ventral tegmental area modulate microdialysate concentrations of dopamine and metabolites in the posterior nucleus accumbens by Laitinen, K, Crawley, J N, Mefford, I N, De Witte, P

“…Neurotensin and cholecystokinin, neuropeptides which coexist with dopamine in many ventral tegmental neurons, were microinjected into the ventral tegmental…”
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Further evidence validating adjuvant arthritis as an experimental model of chronic pain in the rat by Colpaert, F C, Meert, T, De Witte, P, Schmitt, P

“…The experiments described here were aimed at further validating adjuvant arthritis as an animal model of chronic pain. It was found that the relative oral…”
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N-tert-butyl-alpha-phenylnitrone administration fails to modify alcohol dependence and alcohol induced hypervascularization by Lamblin, F, Pascolo, C, Verheyden, C, De Witte, P

“…Chronic alcoholization by ethyl-alcohol inhalation was used to study the properties of a spin-trapping agent on different alcohol manifestations in rat. The…”
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Inhibition of enkephalin metabolism and activation of mu- or delta-opioid receptors elicit opposite effects on reward and motility in the ventral mesencephalon by Heidbreder, C, Gewiss, M, Lallemand, S, Roques, B P, De Witte, P

“…The coexistence of endogenous opioid systems and dopaminergic neurones in the midbrain tegmental area suggests functional interactions between dopamine and…”
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Kelatorphan, a potent enkephalinases inhibitor, and opioid receptor agonists DAGO and DTLET, differentially modulate self-stimulation behaviour depending on the site of administration by de Witte, P, Heidbreder, C, Roques, B P

“…Endogenous enkephalins have been found in the perikaryon of the mesolimbic dopaminergic ventral tegmental area and in axonal terminals in the nucleus…”
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Differential effects of caerulein and bombesin on the ethanol intake in the rat by Gewiss, M, Heidbreder, C, De Witte, P

“…Male Wistar rats were allowed to drink either water or water mixed with ethyl alcohol (4%, 8% and 12%) as part of a water-deprived procedure. The decapeptide…”
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Regional amines levels in the rat brain following intra-accumbens cholecystokinin and intraperitoneal amphetamine pre-treatment by Heidbreder, C, Gewiss, M, De Potter, W, De Witte, P

“…Cholecystokinin octapeptide (CCK8) coexists with dopamine (DA) in a subpopulation of mesolimbic DA neurons including the projections to the nucleus accumbens…”
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Brain stimulation as the reinforcer in alcohol-saline discrimination by De Witte, P

“…Male Wistar rats were trained to discriminate intraperitoneal injections of 1 g/kg alcohol from saline injections. The reward that reinforced correct choices…”
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Cortical microvascular changes in chronological aging, cortical insults and chronic alcohol intoxication in rats. Effects of antihypoxic drug on these phenomena by De Witte, P, Gewiss, M, Heidbreder, C

“…Chronic alcohol pulmonary exposure in rats produced a cortical hypervascularization from one to four weeks after the onset of the alcoholization procedure…”
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Perceptual cues of reinforcing brain stimulations in the postero-lateral area of the hypothalamus by De Witte, P

“…In order to study the perception of intracranial reward in the rat, a rewarding hypothalamic brain stimulation served as conditioned stimulus (CS) in an…”
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Effects of variations of reinforcement magnitude on alcohol discrimination using intracranial stimulation as the reinforcer by De Witte, P, Gewiss, M

“…Male Wistar rats were trained to discriminate intraperitoneal injections of 2 g/kg of alcohol from 0.5 g/kg alcohol injections. Intracranial stimulation in the…”
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Compensatory effects of hypothalamic rewarding stimulation during concomitant painful footshock by de Witte, P

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