Search Results - "De Witt, C"

Single-cell multimodal glioma analyses identify epigenetic regulators of cellular plasticity and environmental stress response by Johnson, Kevin C., Anderson, Kevin J., Courtois, Elise T., Gujar, Amit D., Barthel, Floris P., Varn, Frederick S., Luo, Diane, Seignon, Martine, Yi, Eunhee, Kim, Hoon, Estecio, Marcos R. H., Zhao, Dacheng, Tang, Ming, Navin, Nicholas E., Maurya, Rahul, Ngan, Chew Yee, Verburg, Niels, de Witt Hamer, Philip C., Bulsara, Ketan, Samuels, Michael L., Das, Sunit, Robson, Paul, Verhaak, Roel G. W.

“…Glioma intratumoral heterogeneity enables adaptation to challenging microenvironments and contributes to therapeutic resistance. We integrated 914 single-cell…”
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Impact of Intraoperative Stimulation Brain Mapping on Glioma Surgery Outcome: A Meta-Analysis by DE WITT HAMER, Philip C, GIL ROBLES, Santiago, ZWINDERMAN, Aeilko H, DUFFAU, Hugues, BERGER, Mitchel S

“…Surgery for infiltrative gliomas aims to balance tumor removal with preservation of functional integrity. The usefulness of intraoperative stimulation mapping…”
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Functional Outcomes and Health-Related Quality of Life Following Glioma Surgery by De Witt Hamer, Philip C, Klein, Martin, Hervey-Jumper, Shawn L, Wefel, Jeffrey S, Berger, Mitchel S

“…Abstract Functional outcome following glioma surgery is defined as how the patient functions or feels. Functional outcome is a coprimary end point of surgery…”
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Small molecule kinase inhibitors in glioblastoma: a systematic review of clinical studies by De Witt Hamer, Philip C

“…The efficacy of small-molecule kinase inhibitors has recently changed standard clinical practice for several solid cancers. Glioblastoma is a solid cancer that…”
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Fast intraoperative histology-based diagnosis of gliomas with third harmonic generation microscopy and deep learning by Blokker, Max, Hamer, Philip C. de Witt, Wesseling, Pieter, Groot, Marie Louise, Veta, Mitko

“…Management of gliomas requires an invasive treatment strategy, including extensive surgical resection. The objective of the neurosurgeon is to maximize tumor…”
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Association between tumor location and neurocognitive functioning using tumor localization maps by Habets, Esther J. J., Hendriks, Eef J., Taphoorn, Martin J. B., Douw, Linda, Zwinderman, Aeilko H., Vandertop, W. Peter, Barkhof, Frederik, De Witt Hamer, Philip C., Klein, Martin

“…Introduction Patients with diffuse glioma often experience neurocognitive impairment already prior to surgery. Pertinent information on whether damage to a…”
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Analysis of the subcomponents and cortical terminations of the perisylvian superior longitudinal fasciculus: a fiber dissection and DTI tractography study by Martino, Juan, De Witt Hamer, Philip C., Berger, Mitchel S., Lawton, Michael T., Arnold, Christine M., de Lucas, Enrique Marco, Duffau, Hugues

“…The anatomy of the perisylvian component of the superior longitudinal fasciculus (SLF) has recently been reviewed by numerous diffusion tensor imaging…”
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Linking late cognitive outcome with glioma surgery location using resection cavity maps by Hendriks, Eef J., Habets, Esther J. J., Taphoorn, Martin J. B., Douw, Linda, Zwinderman, Aeilko H., Vandertop, W. Peter, Barkhof, Frederik, Klein, Martin, De Witt Hamer, Philip C.

“…Patients with a diffuse glioma may experience cognitive decline or improvement upon resective surgery. To examine the impact of glioma location, cognitive…”
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Because I Am Worth It: A Theoretical Framework and Empirical Review of a Justification-Based Account of Self-Regulation Failure by De Witt Huberts, Jessie C., Evers, Catharine, De Ridder, Denise T. D.

“…Self-regulation failure is often explained as being overwhelmed by impulse. The present article proposes a novel pathway, presenting a theoretical framework…”
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Resection probability maps for quality assessment of glioma surgery without brain location bias by De Witt Hamer, Philip C, Hendriks, Eef J, Mandonnet, Emmanuel, Barkhof, Frederik, Zwinderman, Aeilko H, Duffau, Hugues

“…Intraoperative brain stimulation mapping reduces permanent postoperative deficits and extends tumor removal in resective surgery for glioma patients…”
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Cognition and resective surgery for diffuse infiltrative glioma: an overview by Klein, Martin, Duffau, Hugues, De Witt Hamer, Philip C.

“…Compared to classical oncological outcome measures such as time to progression and survival, the importance of cognitive functioning in patients with diffuse…”
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Is the human left middle longitudinal fascicle essential for language? A brain electrostimulation study by De Witt Hamer, Philip C., Moritz-Gasser, Sylvie, Gatignol, Peggy, Duffau, Hugues

“…Human brain pathways required for language processing are poorly known. A new white matter tract in humans, the middle longitudinal fascicle, has recently been…”
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Between-hospital variation in mortality and survival after glioblastoma surgery in the Dutch Quality Registry for Neuro Surgery by De Witt Hamer, Philip C., Ho, Vincent K. Y., Zwinderman, Aeilko H., Ackermans, Linda, Ardon, Hilko, Boomstra, Sytske, Bouwknegt, Wim, van den Brink, Wimar A., Dirven, Clemens M., van der Gaag, Niels A., van der Veer, Olivier, Idema, Albert J. S., Kloet, Alfred, Koopmans, Jan, ter Laan, Mark, Verstegen, Marco J. T., Wagemakers, Michiel, Robe, Pierre A. J. T.

“…Purpose Standards for surgical decisions are unavailable, hence treatment decisions can be personalized, but also introduce variation in treatment and outcome…”
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The genomic profile of human malignant glioma is altered early in primary cell culture and preserved in spheroids by De Witt Hamer, P C, Van Tilborg, A A G, Eijk, P P, Sminia, P, Troost, D, Van Noorden, C J F, Ylstra, B, Leenstra, S

“…Screening of therapeutics relies on representative cancer models. The representation of human glioblastoma by in vitro cell culture models is questionable. We…”
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In Silico Analysis of Kinase Expression Identifies WEE1 as a Gatekeeper against Mitotic Catastrophe in Glioblastoma by Mir, Shahryar E., De Witt Hamer, Philip C., Krawczyk, Przemek M., Balaj, Leonora, Claes, An, Niers, Johanna M., Van Tilborg, Angela A.G., Zwinderman, Aeilko H., Geerts, Dirk, Kaspers, Gertjan J.L., Peter Vandertop, W., Cloos, Jacqueline, Tannous, Bakhos A., Wesseling, Pieter, Aten, Jacob A., Noske, David P., Van Noorden, Cornelis J.F., Würdinger, Thomas

“…Kinases execute pivotal cellular functions and are therefore widely investigated as potential targets in anticancer treatment. Here we analyze the kinase gene…”
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Oscillatory brain activity associates with neuroligin-3 expression and predicts progression free survival in patients with diffuse glioma by Derks, Jolanda, Wesseling, Pieter, Carbo, Ellen W. S., Hillebrand, Arjan, van Dellen, Edwin, de Witt Hamer, Philip C., Klein, Martin, Schenk, Geert J., Geurts, Jeroen J. G., Reijneveld, Jaap C., Douw, Linda

“…Introduction Diffuse gliomas have local and global effects on neurophysiological brain functioning, which are often seen as ‘passive’ consequences of the…”
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Non-invasively measured brain activity and radiological progression in diffuse glioma by Numan, T., Kulik, S. D., Moraal, B., Reijneveld, J. C., Stam, C. J., de Witt Hamer, P. C., Derks, J., Bruynzeel, A. M. E., van Linde, M. E., Wesseling, P., Kouwenhoven, M. C. M., Klein, M., Würdinger, T., Barkhof, F., Geurts, J. J. G., Hillebrand, A., Douw, L.

“…Non-invasively measured brain activity is related to progression-free survival in glioma patients, suggesting its potential as a marker of glioma progression…”
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Preoperative Resectability Estimates of Nonenhancing Glioma by Neurosurgeons and a Resection Probability Map by Hendriks, Eef J, Idema, Sander, Hervey-Jumper, Shawn L, Bernat, Anne-Laure, Zwinderman, Aeilko H, Barkhof, Frederik, Vandertop, W Peter, Mandonnet, Emmanuel, Duffau, Hugues, Berger, Mitchel S, De Witt Hamer, Philip C

“…Preoperative interpretation of resectability of diffuse nonenhancing glioma is primarily based on individual surgical expertise. To compare the accuracy and…”
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miR-101 is down-regulated in glioblastoma resulting in EZH2-induced proliferation, migration, and angiogenesis by Smits, Michiel, Nilsson, Jonas, Mir, Shahryar E, van der Stoop, Petra M, Hulleman, Esther, Niers, Johanna M, de Witt Hamer, Phillip C, Marquez, Victor E, Cloos, Jacqueline, Krichevsky, Anna M, Noske, David P, Tannous, Bakhos A, Würdinger, Thomas

“…Glioblastoma (GBM) is a malignant brain tumor with dismal prognosis. GBM patients have a median survival of less than 2 years. GBM is characterized by fast…”
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License to sin: Self-licensing as a mechanism underlying hedonic consumption by de Witt Huberts, Jessie C., Evers, Catharine, De Ridder, Denise T. D.

“…Hedonic overconsumption is often considered to be caused by impulsive factors. The current paper investigates whether self‐licensing, relying on reasons to…”
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