Search Results - "De Vreese, Karen"

Diagnostic performance of a CSF-biomarker panel in autopsy-confirmed dementia by Engelborghs, Sebastiaan, De Vreese, Karen, Van de Casteele, Tom, Vanderstichele, Hugo, Van Everbroeck, Bart, Cras, Patrick, Martin, Jean-Jacques, Vanmechelen, Eugeen, De Deyn, Peter Paul

“…Abstract To establish diagnostic performance of the cerebrospinal fluid (CSF) biomarkers β-amyloid peptide (Aβ1–42 ), total tau-protein (T-tau) and tau…”
Get full text

Monitoring Drug Resistance in Chronic Hepatitis B Virus (HBV)-Infected Patients during Lamivudine Therapy: Evaluation of Performance of INNO-LiPA HBV DR Assay by LOK, Anna S. F, ZOULIM, Fabien, LOCARNINI, Stephen, MANGIA, Alessandra, NIRO, Grazia, DECRAEMER, Hilde, MAERTENS, Geert, HULSTAERT, Frank, DE VREESE, Karen, SABLON, Erwin

“…Article Usage Stats Services JCM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Synthesis and Structure-Activity Relationships of Phenylenebis(methylene)-Linked Bis-Tetraazamacrocycles That Inhibit HIV Replication. Effects of Macrocyclic Ring Size and Substituents on the Aromatic Linker by Bridger, Gary J, Skerlj, Renato T, Thornton, David, Padmanabhan, Sreenivasan, Martellucci, Stephen A, Henson, Geoffrey W, Abrams, Michael J, Yamamoto, Naohiko, Vreese, Karen De

“…We have previously described the potent and selective inhibition of several strains of human immunodeficiency virus type 1 (HIV-1) and type 2 (HIV-2) by…”
Get full text

Development of resistance of human immunodeficiency virus type 1 to dextran sulfate associated with the emergence of specific mutations in the envelope gp120 glycoprotein by Este, J A, Schols, D, De Vreese, K, Van Laethem, K, Vandamme, A M, Desmyter, J, De Clercq, E

“…Polyanionic compounds are known to inhibit the binding of human immunodeficiency virus (HIV) to CD4+ cells and the subsequent fusion step between the virus and…”
Get more information

Performance characteristics of updated INNO-LiPA assays for molecular typing of human leukocyte antigen A (HLA-A), HLA-B, and HLA-DQB1 alleles by De Vreese, Karen, Barylski, Rachel, Pughe, Fiona, Bläser, Miriam, Evans, Colin, Norton, John, Semana, Gilbert, Holman, Richard, Loiseau, Pascale, Masson, Dominique, Gielis, Mieke, De Brauwer, Annelies, De Canck, Ilse, Verpooten, Gonda, Hulstaert, Frank

“…We carried out a multicenter performance evaluation of three new DNA-based human leukocyte antigen (HLA) typing assays: INNO-LiPA HLA-A Update, INNO-LiPA HLA-B…”
Get full text

The molecular target of bicyclams, potent inhibitors of human immunodeficiency virus replication by de Vreese, K, Kofler-Mongold, V, Leutgeb, C, Weber, V, Vermeire, K, Schacht, S, Anné, J, de Clercq, E, Datema, R, Werner, G

“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

Potent and Highly Selective Human Immunodeficiency Virus Type 1 (HIV-1) Inhibition by a Series of α-Anilinophenylacetamide Derivatives Targeted at HIV-1 Reverse Transcriptase by Pauwels, Rudi, Andries, Koen, Debyser, Zeger, Van Daele, Paul, Schols, Dominique, Stoffels, Paul, De Vreese, Karen, Woestenborghs, Robert, Vandamme, Anne-Mieke, Cornelus G. M. Janssen, Anne, Jef, Cauwenbergh, Geert, Desmyter, Jan, Heykants, Jozef, Marcel A. C. Janssen, De Clercq, Erik, Paul A. J. Janssen

“…In vitro evaluation of a large chemical library of pharmacologically acceptable prototype compounds in a high-capacity, cellular-based screening system has led…”
Get full text

O3-01-06: Diagnostic performance of a CSF-biomarker panel compared to clinical diagnosis in 100 autopsy-confirmed dementia cases by Engelborghs, Sebastiaan, De Vreese, Karen, Van de Casteele, Tom, Vanderstichele, Hugo, Van Everbroeck, Bart, Cras, Patrick, Martin, Jean-Jacques, Vanmechelen, Eugeen, De Deyn, Peter P.

Get full text

Monitoring drug resistance in hepatitis B virus-infected patients during antiviral therapy: multi-center evaluation of the INNO-LiPA HBV-DR by Sablon, Erwin R., Lok, Anna S., Locarnini, Stephen, Zoulim, Fabien, Mangia, Alessandra, De Vreese, Karen, Maertens, Geert

Get full text

Analytical performance and clinical utility of the INNOTEST PHOSPHO-TAU181P assay for discrimination between Alzheimer's disease and dementia with Lewy bodies by Vanderstichele, Hugo, De Vreese, Karen, Blennow, Kaj, Andreasen, Niels, Sindic, Christian, Ivanoiu, Adrian, Hampel, Harald, Bürger, Katharina, Parnetti, Lucilla, Lanari, Alessia, Padovani, Allesandro, DiLuca, Monica, Bläser, Miriam, Olsson, Annika Ohrfelt, Pottel, Hans, Hulstaert, Frank, Vanmechelen, Eugeen

“…Total tau (T-tau) and beta-amyloid((1-42)) (Abeta(1-42)) levels in cerebrospinal fluid (CSF) can differentiate Alzheimer's disease (AD) from normal aging or…”
Get more information

Synthesis and Structure−Activity Relationships of Phenylenebis(methylene)- Linked Bis-tetraazamacrocycles That Inhibit Human Immunodeficiency Virus Replication. 2. Effect of Heteroaromatic Linkers on the Activity of Bicyclams by Bridger, Gary J, Skerlj, Renato T, Padmanabhan, Sreenivasan, Martellucci, Stephen A, Henson, Geoffrey W, Abrams, Michael J, Joao, Heidi C, Witvrouw, Myriam, De Vreese, Karen, Pauwels, Rudi, De Clercq, Erik

“…A series of bicyclam analogs connected through a heteroaromatic linker have been synthesized and evaluated for their inhibitory effects on HIV-1 (IIIB) and…”
Get full text

Sensitivity of human immunodeficiency virus to bicyclam derivatives is influenced by the three-dimensional structure of gp120 by DE VREESE, K, VAN NERUM, I, VERMEIRE, K, ANNE, J, DE CLERCQ, E

“…Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon…”
Get full text

The bicyclams, a new class of potent human immunodeficiency virus inhibitors, block viral entry after binding by De Vreese, Karen, Reymen, Diane, Griffin, Philip, Steinkasserer, Alexander, Werner, Gudrun, Bridger, Gary J., Esté, José, James, William, Henson, Geoffrey W., Desmyter, Jan, Anné, Jozef, De Clercq, Erik

“…The bicyclams represent a new class of highly potent and selective HIV inhibitors. Time-of-addition experiments have previously shown that these compounds…”
Get full text

Antiviral activity of the bicyclam derivative JM3100 against drug-resistant strains of human immunodeficiency virus type 1 by Esté, JoséA., De Vreese, Karen, Witvrouw, Myriam, Schmit, Jean-Claude, Vandamme, Anne-Mieke, Anné, Jozef, Desmyter, Jan, Henson, Geoffrey W., Bridger, Gary, De Clercq, Erik

“…Bicyclams have recently been identified as potent and selective inhibitors of human immunodeficiency virus type 1 (HIV-1) and type 2 (HIV-2) replication. The…”
Get full text

A two plasmid co-expression system in Escherichia coli for the production of virion-like reverse transcriptase of the human immunodeficiency virus type 1 by Jonckheere, Heidi, De Vreese, Karen, Debyser, Zeger, Vandekerckhove, Joël, Balzarini, Jan, Desmyter, Jan, De Clercq, Erik, Anné, Jozef

“…Many bacterial expression systems have been developed to study the reverse transcriptase (RT) of human immunodeficiency virus type 1 (HIV-1). This enzyme…”
Get full text

Resistance of human immunodeficiency virus type 1 reverse transcriptase to TIBO derivatives induced by site-directed mutagenesis by de Vreese, K, Debyser, Z, Vandamme, A M, Pauwels, R, Desmyter, J, de Clercq, E, Anné, J

“…The reverse transcriptase (RT) of human immunodeficiency virus type 1 (HIV-1) is the target enzyme for the tetrahydro-imidazo[4,5,1-jk][1,4]-…”
Get more information

Characterization of HIV-1 strains isolated from patients treated with TIBO R82913 by Vandamme, A M, Debyser, Z, Pauwels, R, De Vreese, K, Goubau, P, Youle, M, Gazzard, B, Stoffels, P A, Cauwenbergh, G F, Anne, J

“…The drug sensitivities of human immunodeficiency virus type 1 (HIV-1) isolates from a group of four untreated and seven TIBO R82913-treated patients were…”
Get more information

Differential inhibitory effects of TIBO derivatives on different strains of simian immunodeficiency virus by Debyser, Zeger, De Vreese, Karen, Pauwels, Rudi, Yamamoto, Naohiko, Anne, Jozef, De Clercq, Erik, Desmyter, Jan

“…Rega Institute for Medical Research, Katholieke Universiteit Leuven, Minderbroedersstraat 10, B-3000 Leuven, Belgium Recently, several classes of compounds…”
Get full text

Quantitative structural activity relationship study of bis-tetraazacyclic compounds. A novel series of HIV-1 and HIV-2 inhibitors by Joao, Heidi C, De Vreese, Karen, Pauwels, Rudi, De Clercq, Erik, Henson, Geoff W, Bridger, Gary J

“…This work describes a study of quantitative structural activity relationships (QSAR) of bis-tetraazamacrocyclic compounds. These compounds represent a novel…”
Get full text