Search Results - "De Vocht, Joke"
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Suicidality among healthcare professionals during the first COVID19 wave
Published in Journal of affective disorders (15-03-2021)“…•We investigate suicidal thoughts and behaviors (STB) among healthcare professionals in the first COVID19 wave in belgium.•30-day STB is estimated at 4%,…”
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Altered perivascular fibroblast activity precedes ALS disease onset
Published in Nature medicine (01-04-2021)“…Apart from well-defined factors in neuronal cells 1 , only a few reports consider that the variability of sporadic amyotrophic lateral sclerosis (ALS)…”
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Specialized multidisciplinary care improves ALS survival in Belgium: a population-based retrospective study
Published in Amyotrophic lateral sclerosis and frontotemporal degeneration (01-05-2024)“…ALS is a neurodegenerative disease characterized by loss of motor neurons, resulting in progressive weakness and wasting of muscles. The average survival time…”
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Positive screens for mental disorders among healthcare professionals during the first covid19 wave in Belgium
Published in Journal of psychiatric research (01-08-2021)“…We examined the manifestation of major depressive disorder, generalized anxiety disorder, substance use disorder, post-traumatic stress disorder, and panic…”
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Moving Toward Multicenter Therapeutic Trials in Amyotrophic Lateral Sclerosis: Feasibility of Data Pooling Using Different Translocator Protein PET Radioligands
Published in Journal of Nuclear Medicine (01-11-2020)“…Neuroinflammation has been implicated in amyotrophic lateral sclerosis (ALS) and can be visualized using translocator protein (TSPO) radioligands. To become a…”
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Publisher Correction: Altered perivascular fibroblast activity precedes ALS disease onset
Published in Nature medicine (01-07-2021)Get full text
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Differences in Cerebral Glucose Metabolism in ALS Patients with and without C9orf72 and SOD1 Mutations
Published in Cells (Basel, Switzerland) (18-03-2023)“…Amyotrophic lateral sclerosis (ALS) is characterized by progressive loss of upper and lower motor neurons. In 10% of patients, the disorder runs in the family…”
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Glucose metabolic brain patterns to discriminate amyotrophic lateral sclerosis from Parkinson plus syndromes
Published in EJNMMI research (13-12-2018)“…Background 18 F-FDG brain PET measures metabolic changes in neurodegenerative disorders and may discriminate between different diseases even at an early stage…”
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Prognostic value of motor and extramotor involvement in ALS
Published in Amyotrophic lateral sclerosis and frontotemporal degeneration (01-02-2024)“…Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder resulting in upper and lower motor neuron loss. ALS often has a focal onset of weakness,…”
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TSPO Versus P2X7 as a Target for Neuroinflammation: An In Vitro and In Vivo Study
Published in Journal of Nuclear Medicine (01-04-2020)“…Neuroinflammation is important in amyotrophic lateral sclerosis (ALS). The P2X7 receptor (P2X7R) is a promising target for neuroinflammation. The objective of…”
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Prognostic relationship of neurofilaments, CHIT1, YKL-40 and MCP-1 in amyotrophic lateral sclerosis
Published in Journal of neurology, neurosurgery and psychiatry (01-06-2022)Get full text
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Combined brain and spinal FDG PET allows differentiation between ALS and ALS mimics
Published in European journal of nuclear medicine and molecular imaging (01-10-2020)“…Purpose Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder with on average a 1-year delay between symptom onset and diagnosis…”
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Use of Multimodal Imaging and Clinical Biomarkers in Presymptomatic Carriers of C9orf72 Repeat Expansion
Published in JAMA neurology (01-08-2020)“…During a time with the potential for novel treatment strategies, early detection of disease manifestations at an individual level in presymptomatic carriers of…”
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Psychopathology in premanifest C9orf72 repeat expansion carriers
Published in Journal of neurology, neurosurgery and psychiatry (01-05-2022)Get full text
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Is there a glucose metabolic signature of spreading TDP-43 pathology in amyotrophic lateral sclerosis?
Published in The quarterly journal of nuclear medicine and molecular imaging (01-03-2020)“…Recently, four neuropathological stages of amyotrophic lateral sclerosis (ALS) with spreading of transactive response DNA-binding protein-43 pathology were…”
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Multicenter validation of [18F]-FDG PET and support-vector machine discriminant analysis in automatically classifying patients with amyotrophic lateral sclerosis versus controls
Published in Amyotrophic lateral sclerosis and frontotemporal degeneration (02-10-2018)“…Objective: 18 F-Fluorodeoxyglucose ( 18 F-FDG) positron emission tomography (PET) single-center studies using support vector machine (SVM) approach to…”
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Altered perivascular fibroblast activity precedes ALS disease onset (vol 27, pg 640, 2021)
Published in NATURE MEDICINE (01-07-2021)Get full text
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Thirty-day suicidal thoughts and behaviours in the Spanish adult general population during the first wave of the Spain COVID-19 pandemic
Published in Epidemiology and psychiatric sciences (17-02-2021)“…To investigate the prevalence of suicidal thoughts and behaviours (STB; i.e. suicidal ideation, plans or attempts) in the Spanish adult general population…”
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