Search Results - "De Vernejoul, M. C."

Osteoporosis in young adults: pathophysiology, diagnosis, and management by Ferrari, S., Bianchi, M. L., Eisman, J. A., Foldes, A. J., Adami, S., Wahl, D. A., Stepan, J. J., de Vernejoul, M.-C., Kaufman, J.-M.

“…Postmenopausal osteoporosis is mainly caused by increased bone remodeling resulting from estrogen deficiency. Indications for treatment are based on low areal…”
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Strontium Ranelate Reduces the Risk of Nonvertebral Fractures in Postmenopausal Women with Osteoporosis: Treatment of Peripheral Osteoporosis (TROPOS) Study by Reginster, J. Y., Seeman, E., De Vernejoul, M. C., Adami, S., Compston, J., Phenekos, C., Devogelaer, J. P., Curiel, M. Diaz, Sawicki, A., Goemaere, S., Sorensen, O. H., Felsenberg, D., Meunier, P. J.

“…Background: Strontium ranelate, a new oral drug shown to reduce vertebral fracture risk in postmenopausal women with osteoporosis, was studied in the Treatment…”
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Effect of oral monthly ibandronate on bone microarchitecture in women with osteopenia—a randomized placebo-controlled trial by Chapurlat, R. D., Laroche, M., Thomas, T., Rouanet, S., Delmas, P. D., de Vernejoul, M.-C.

“…Summary We have examined the effect of oral monthly ibandronate on distal radius and tibia microarchitecture with high-resolution peripheral quantitative…”
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serotonin 5-HT₂B receptor controls bone mass via osteoblast recruitment and proliferation by Collet, C, Schiltz, C, Geoffroy, V, Maroteaux, L, Launay, J.-M, de Vernejoul, M.-C

“…The monoamine serotonin (5-HT), a well-known neurotransmitter, is also important in peripheral tissues. Several studies have suggested that 5-HT is involved in…”
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Bone status and fractures in 85 adults with Wilson’s disease by Quemeneur, A.-S., Trocello, J.-M., Ea, H.-K., Ostertag, A., Leyendecker, A., Duclos-Vallée, J.-C., de Vernejoul, M.-C., Woimant, F., Lioté, F.

“…Summary Wilson’s disease is characterized by copper deposition, especially in the liver and central nervous system. We assessed the prevalent fractures and…”
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ClC-7 expression levels critically regulate bone turnover, but not gastric acid secretion by Supanchart, C, Wartosch, L, Schlack, C, Kühnisch, J, Felsenberg, D, Fuhrmann, J.C, de Vernejoul, M.-C, Jentsch, T.J, Kornak, U

“…Abstract Mutations in the 2Cl− /1H+ -exchanger ClC-7 impair osteoclast function and cause different types of osteoclast-rich osteopetrosis. However, it is…”
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BMD Is Reduced in HIV‐Infected Men Irrespective of Treatment by Amiel, C, Ostertag, A, Slama, L, Baudoin, C, N'Guyen, T, Lajeunie, E, Neit‐Ngeilh, L, Rozenbaum, W, De Vernejoul, MC

“…Osteoporosis has be reported to be a complication of active antiretroviral therapy of HIV infection. We studied 148 HIV‐infected men stratified according to…”
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Strontium ranelate decreases the incidence of new caudal vertebral fractures in a growing mouse model with spontaneous fractures by improving bone microarchitecture by Geoffroy, V, Chappard, D, Marty, C, Libouban, H, Ostertag, A, Lalande, A, de Vernejoul, M.-C

“…Summary Young mice over-expressing Runx2 fail to gain bone relative to wild type mice with growth and present spontaneous fractures. It allows, for the first…”
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Quality of life in patients with vertebral fractures : Validation of the Quality of Life Questionnaire of the European Foundation for Osteoporosis (QUALEFFO) by LIPS, P, COOPER, C, MCCLOSKEY, E, MINNE, H, REEVE, J, REGINSTER, J.-Y, SCHOLZ, M, TODD, C, DE VERNEJOUL, M. C, WIKLUND, I, AGNUSDEI, D, CAULIN, F, EGGER, P, JOHNELL, O, KANIS, J. A, KELLINGRAY, S, LEPLEGE, A, LIBERMAN, U. A

“…Vertebral fractures may be minor or lead to pain, decreased physical function, immobility, social isolation and depression, which together contribute to…”
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Polymorphisms in the CLCN7 Gene Modulate Bone Density in Postmenopausal Women and in Patients with Autosomal Dominant Osteopetrosis Type II by Kornak, U., Ostertag, A., Branger, S., Benichou, O., de Vernejoul, M.-C.

“…Context: Genetic factors are important determinants of bone mineral density (BMD). The fact that mutations in the ClC-7 chloride channel cause autosomal…”
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Strontium ranelate: Dose-dependent effects in established postmenopausal vertebral osteoporosis: A 2-year randomized placebo controlled trial by MEUNIER, P. J, SLOSMAN, D. O, REGINSTER, J. Y, DELMAS, P. D, SEBERTT, J. L, BRANDI, M. L, ALBANESE, C, LORENC, R, PORS-NIELSEN, S, DE VERNEJOUL, M. C, ROCES, A

“…The aim of the strontium ranelate (SR) for treatment of osteoporosis (STRATOS) trial was to investigate the efficacy and safety of different doses of SR, a…”
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An intermediate form of juvenile Paget's disease caused by a truncating TNFRSF11B mutation by Janssens, K., de Vernejoul, M.-C., de Freitas, F., Vanhoenacker, F., Van Hul, W.

“…Juvenile Paget's disease (JPD) is a rare condition with an autosomal recessive mode of inheritance. Typically presenting in infancy or early childhood, the…”
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Bone Mass in Middle‐Aged Osteoporotic Men and Their Relatives: Familial Effect by Cohen‐Solal, M. E., Baudoin, C., Omouri, M., Kuntz, D., de Vernejoul, M. C.

“…Severe idiopathic osteoporosis in middle‐aged men is still poorly understood. The aim of this study was to assess the contribution of genetic factors in these…”
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LRP5 gene polymorphisms and idiopathic osteoporosis in men by Ferrari, S.L., Deutsch, S., Baudoin, C., Cohen-Solal, M., Ostertag, A., Antonarakis, S.E., Rizzoli, R., de Vernejoul, M.C.

“…Mutations in the low-density lipoprotein receptor-related protein 5 gene ( LRP5) have demonstrated the role of LRP5 in bone mass acquisition. LRP5 variants…”
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Type II autosomal dominant osteopetrosis (Albers-Schönberg disease): clinical and radiological manifestations in 42 patients by Bénichou, O.D, Laredo, J.D, de Vernejoul, M.C

“…Type II autosomal dominant osteopetrosis (ADO II, Albers-Schönberg disease) is a genetic condition characterized by generalized osteosclerosis predominating in…”
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A combination of low doses of 17β-estradiol and norethisterone acetate prevents bone loss and normalizes bone turnover in postmenopausal women by DELMAS, P. D, CONFAVREUX, E, GARNERO, P, FARDELLONE, P, DE VERNEJOUL, M.-C, CORMIER, C, ARCE, J.-C

“…The effects of 17 beta-estradiol (E2) 1 mg combined with low doses of norethisterone acetate (NETA) on postmenopausal bone loss and turnover were investigated…”
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Bone mineral density in patients with rapidly destructive or common hip osteoarthritis by RICHETTE, P, VICAUT, E, DE VERNEJOUL, M.-C, ORCEL, P, BARDIN, T

“…Recent findings that subchondral insufficiency fracture in the femoral head may precede rapid chondrolysis suggest a role for systemic low bone mass in the…”
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Disrupted trabecular bone micro‐architecture in middle‐aged male HIV‐infected treated patients by Sellier, P, Ostertag, A, Collet, C, Trout, H, Champion, K, Fernandez, S, Lopes, A, Morgand, M, Clevenbergh, P, Evans, J, Souak, S, Vernejoul, M‐C, Bergmann, J‐F

“…Objectives HIV‐infected individuals are at increased risk of incident fractures. Evaluation of trabecular bone micro‐architecture is an important tool to…”
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Quality of life as outcome in the treatment of osteoporosis : The development of a questionnaire for quality of life by the European Foundation for Osteoporosis by LIPS, P, COOPER, C, REGINSTER, J. Y, DE VERNEJOUL, M. C, WIKLUND, I, AGNUSDEI, D, CAULIN, F, EGGER, P, JOHNELL, O, KANIS, J. A, LIBERMAN, U, MINNE, H, REEVE, J

“…The morbidity of osteoporosis is caused by fractures. Vertebral fractures lead to pain and disability and a decrease in quality of life. A Working Party of the…”
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Comparison of four morphometric definitions and a semiquantitative consensus reading for assessing prevalent vertebral fractures by GRADOS, F, ROUX, C, DE VERNEJOUL, M. C, UTARD, G, SEBERT, J. L, FARDELLONE, P

“…The assessment of vertebral fracture in patients with osteoporosis by conventional radiography has been improved over the past 10 years using either the…”
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