Search Results - "De Theije, C"

Hypoxia impairs adaptation of skeletal muscle protein turnover- and AMPK signaling during fasting-induced muscle atrophy by de Theije, C C, Schols, A M W J, Lamers, W H, Neumann, D, Köhler, S E, Langen, R C J

“…Hypoxemia in humans may occur during high altitude mountaineering and in patients suffering from ventilatory insufficiencies such as cardiovascular- or…”
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Cigarette smoke extract induces a phenotypic shift in epithelial cells; involvement of HIF1α in mesenchymal transition by Eurlings, Irene M J, Reynaert, Niki L, van den Beucken, Twan, Gosker, Harry R, de Theije, C C, Verhamme, Fien M, Bracke, Ken R, Wouters, Emiel F M, Dentener, Mieke A

“…In COPD, matrix remodeling contributes to airflow limitation. Recent evidence suggests that next to fibroblasts, the process of epithelial-mesenchymal…”
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Differential sensitivity of oxidative and glycolytic muscles to hypoxia-induced muscle atrophy by de Theije, C C, Langen, R C J, Lamers, W H, Gosker, H R, Schols, A M W J, Köhler, S E

“…Hypoxia as a consequence of acute and chronic respiratory disease has been associated with muscle atrophy. This study investigated the sensitivity of oxidative…”
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Gut-to-Brain Axis in Autism Spectrum Disorders: Central Role for the Microbiome by Kraneveld, A D, Szklany, K, de Theije, C G M, Garssen, J

“…Autism spectrum disorders (ASDs) are neurodevelopmental disorders, which occur in early childhood and persist into adulthood. Although the etiology of these…”
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Dolphin CONTINUE: a multi-center randomized controlled trial to assess the effect of a nutritional intervention on brain development and long-term outcome in infants born before 30 weeks of gestation by Janson, E, Koolschijn, P C M P, Schipper, L, Boerma, T D, Wijnen, F N K, de Boode, W P, van den Akker, C H P, Licht-van der Stap, R G, Nuytemans, D H G M, Onland, W, Obermann-Borst, S A, Dudink, J, de Theije, C G M, Benders, M J N L, van der Aa, N E

“…Preterm born infants are at risk for brain injury and subsequent developmental delay. Treatment options are limited, but optimizing postnatal nutrition may…”
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SARS-CoV-2 cellular and humoral responses in vaccine-naive individuals during the first two waves of COVID-19 infections in the southern region of The Netherlands: a cross-sectional population-based study by Hanssen, D A T, Arts, K, Nix, W H V, Sweelssen, N N B, Welbers, T T J, de Theije, C, Wieten, L, Pagen, D M E, Brinkhues, S, Penders, J, Dukers-Muijrers, N H T M, Hoebe, C J P A, Savelkoul, P H M, van Loo, I H M

“…With the emergence of highly transmissible variants of concern, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) still poses a global threat of…”
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Skeletal muscle unloading results in increased mitophagy and decreased mitochondrial biogenesis regulation by Leermakers, Pieter A., Kneppers, Anita E.M., Schols, Annemie M.W.J., Kelders, Marco C.J.M., Theije, Chiel C., Verdijk, Lex B., Loon, Luc J.C., Langen, Ramon C.J., Gosker, Harry R.

“…Introduction Physical inactivity significantly contributes to loss of muscle mass and performance in bed‐bound patients. Loss of skeletal muscle mitochondrial…”
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Effect of chronic hypoxia on RAGE and its soluble forms in lungs and plasma of mice by Gopal, P., Gosker, H.R., Theije, C.C. de, Eurlings, I.M., Sell, D.R., Monnier, V.M., Reynaert, N.L.

“…The receptor for advanced glycation end products (RAGE) is a multi-ligand receptor. Alternative splicing and enzymatic shedding produce soluble forms that…”
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Requirement of Nuclear Factor of Activated T-cells in Calcineurin-mediated Cardiomyocyte Hypertrophy by van Rooij, Eva, Doevendans, Pieter A, de Theije, Chiel C, Babiker, Fawzi A, Molkentin, Jeffery D, de Windt, Leon J

“…The calcium-activated phosphatase calcineurin has been implicated as a critical intracellular signal transducer of cardiomyocyte hypertrophy. Although previous…”
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Alterations in Skeletal Muscle Oxidative Phenotype in Mice Exposed to 3 Weeks of Normobaric Hypoxia by Slot, Ilse G.M., Schols, Annemie M.W.J., de Theije, Chiel C., Snepvangers, Frank J.M., Gosker, Harry R.

“…Skeletal muscle of patients with chronic respiratory failure is prone to loss of muscle mass and oxidative phenotype. Tissue hypoxia has been associated with…”
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Differential regulation of muscle protein turnover in response to emphysema and acute pulmonary inflammation by Ceelen, Judith J M, Schols, Annemie M W J, van Hoof, Stefan J, de Theije, Chiel C, Verhaegen, Frank, Langen, Ramon C J

“…Exacerbations in COPD are often accompanied by pulmonary and systemic inflammation, and associated with increased susceptibility to and prevalence of weight…”
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Pulmonary inflammation-induced loss and subsequent recovery of skeletal muscle mass require functional poly-ubiquitin conjugation by Ceelen, Judith J M, Schols, Annemie M W J, Thielen, Nathalie G M, Haegens, Astrid, Gray, Douglas A, Kelders, Marco C J M, de Theije, Chiel C, Langen, Ramon C J

“…Pulmonary inflammation in response to respiratory infections can evoke muscle wasting. Increased activity of the ubiquitin (Ub)-proteasome system (UPS) and the…”
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Increased Myogenic and Protein Turnover Signaling in Skeletal Muscle of Chronic Obstructive Pulmonary Disease Patients With Sarcopenia by Kneppers, Anita E.M., MSc, Langen, Ramon C.J., PhD, Gosker, Harry R., PhD, Verdijk, Lex B., PhD, Cebron Lipovec, Nanca, PhD, Leermakers, Pieter A., MSc, Kelders, Marco C.J.M., BSc, de Theije, Chiel C., PhD, Omersa, Daniel, MD, Lainscak, Mitja, PhD, Schols, Annemie M.W.J., PhD

“…Abstract Background Sarcopenia was recently recognized as an independent condition by an International Classification of Diseases, Tenth Revision, Clinical…”
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Supplementing exposure to hypoxia with a copper depleted diet does not exacerbate right ventricular remodeling in mice by Poels, Ella M, Bitsch, Nicole, Slenter, Jos M, Kooi, M Eline, de Theije, Chiel C, de Windt, Leon J, van Empel, Vanessa P M, da Costa Martins, Paula A

“…Pulmonary hypertension and subsequent right ventricular (RV) failure are associated with high morbidity and mortality. Prognosis is determined by occurrence of…”
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Molecular signalling towards mitochondrial breakdown is enhanced in skeletal muscle of patients with chronic obstructive pulmonary disease (COPD) by Leermakers, P. A., Schols, A. M. W. J., Kneppers, A. E. M., Kelders, M. C. J. M., de Theije, C. C., Lainscak, M., Gosker, H. R.

“…Loss of skeletal muscle mitochondrial oxidative capacity is well-established in patients with COPD, but the role of mitochondrial breakdown herein is largely…”
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Timed fetal inflammation and postnatal hypoxia cause cortical white matter injury, interneuron imbalances, and behavioral deficits in a double-hit rat model of encephalopathy of prematurity by Brandt, M.J.V., Kosmeijer, C.M., Achterberg, E.J.M., de Theije, C.G.M., Nijboer, C.H.

“…Extreme preterm birth-associated adversities are a major risk factor for aberrant brain development, known as encephalopathy of prematurity (EoP), which can…”
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Nuclear transcription factor κ B activation and protein turnover adaptations in skeletal muscle of patients with progressive stages of lung cancer cachexia by Op den Kamp, Céline M, Langen, Ramon C, Snepvangers, Frank J, de Theije, Chiel C, Schellekens, Johanna M, Laugs, Fabian, Dingemans, Anne-Marie C, Schols, Annemie M

“…Background: Experimental models of cancer cachexia have indicated that systemic inflammation induces muscle-protein breakdown and wasting via muscular nuclear…”
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Biobanking in Molecular Biomarker Research for the Early Detection of Cancer by Lommen, Kim, Odeh, Selena, Theije, Chiel C de, Smits, Kim M

“…Although population-wide screening programs for several cancer types have been implemented in multiple countries, screening procedures are invasive,…”
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Glucocorticoid Receptor Signaling Impairs Protein Turnover Regulation in Hypoxia-Induced Muscle Atrophy in Male Mice by de Theije, Chiel C, Schols, Annemie M W J, Lamers, Wouter H, Ceelen, Judith J M, van Gorp, Rick H, Hermans, J J Rob, Köhler, S Elonore, Langen, Ramon C J

“…Hypoxemia may contribute to muscle wasting in conditions such as chronic obstructive pulmonary disease. Muscle wasting develops when muscle proteolysis exceeds…”
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NF-κB-mediated metabolic remodelling in the inflamed heart in acute viral myocarditis by Remels, Alexander H.V., Derks, Wouter J.A., Cillero-Pastor, Berta, Verhees, Koen J.P., Kelders, Marco C., Heggermont, Ward, Carai, Paolo, Summer, Georg, Ellis, Shane R., de Theije, Chiel C., Heeren, Ron M.A., Heymans, Stephane, Papageorgiou, Ana P., van Bilsen, Marc

“…Acute viral myocarditis (VM), characterised by leukocyte infiltration and dysfunction of the heart, is an important cause of sudden cardiac death in young…”
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