Search Results - "De Tata, V."

Modulation of Autophagy Influences the Function and Survival of Human Pancreatic Beta Cells Under Endoplasmic Reticulum Stress Conditions and in Type 2 Diabetes by Bugliani, M, Mossuto, S, Grano, F, Suleiman, M, Marselli, L, Boggi, U, De Simone, P, Eizirik, D L, Cnop, M, Marchetti, P, De Tata, V

“…Autophagy is the major mechanism involved in degradation and recycling of intracellular components, and its alterations have been proposed to cause beta cell…”
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Expression of γ-glutamyltransferase in cancer cells and its significance in drug resistance by Pompella, A., De Tata, V., Paolicchi, A., Zunino, F.

“…The expression of γ-glutamyltransferase (GGT), a cell surface enzyme involved in cellular glutathione homeostasis, is often significantly increased in human…”
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Prevention by metformin of alterations induced by chronic exposure to high glucose in human islet beta cells is associated with preserved ATP/ADP ratio by Masini, M, Anello, M, Bugliani, M, Marselli, L, Filipponi, F, Boggi, U, Purrello, F, Occhipinti, M, Martino, L, Marchetti, P, De Tata, V

“…Abstract Aim We have explored whether the insulin secretory defects induced by glucotoxicity in human pancreatic islets could be prevented by metformin and…”
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The aryl receptor inhibitor epigallocatechin-3-gallate protects INS-1E beta-cell line against acute dioxin toxicity by Martino, L., Masini, M., Novelli, M., Giacopelli, D., Beffy, P., Masiello, P., De Tata, V.

“…•We investigated the mechanisms of dioxin acute toxicity in pancreatic beta cells.•We tested the protective effect of the AhR inhibitor…”
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Insufficient adaptive capability of pancreatic endocrine function in dexamethasone-treated ageing rats by Novelli, M, De Tata, V, Bombara, M, Lorenzini, A, Masini, M, Pollera, M, Bergamini, E, Masiello, P

“…This study was aimed at exploring the capability of the pancreatic endocrine adaptive mechanisms of ageing Sprague-Dawley rats to counteract the metabolic…”
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Persistent correction of hyperglycemia in streptozotocin-nicotinamide-induced diabetic mice by a non-conventional radical scavenger by Novelli, M., Bonamassa, B., Masini, M., Funel, N., Canistro, D., De Tata, V., Martano, M., Soleti, A., Campani, D., Paolini, M., Masiello, P.

“…We previously reported that in a diabetes mouse model, characterised by moderate hyperglycaemia and reduced β-cell mass, the radical scavenger…”
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Dehydroascorbate protection against dioxin-induced toxicity in the b-cell line INS-1E by Martino, L, Novelli, M, Masini, M, Chimenti, D, Piaggi, S, Masiello, P, De Tata, V

“…Oxidative stress has been proposed as a mechanism of the toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). The aim of this research was to evaluate the…”
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Calorie restriction counteracts the impairment of adipocyte insulin-stimulated lipogenesis in aging rats, but not that induced by dexamethasone treatment by NOVELLI, M, DE TATA, V, MASIELLO, P

“…In order to detect metabolic derangements that could be implicated in the pathogenesis of age-related insulin resistance, insulin-stimulated lipogenesis was…”
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Dexamethasone-induced insulin resistance and pancreatic adaptive response in aging rats are not modified by oral vanadyl sulfate treatment by BARBERA, Michele, FIERABRACCI, Vanna, NOVELLI, Michela, BOMBARA, Maria, MASIELLO, Pellegrino, BERGAMINI, Ettore, DE TATA, Vincenzo

“…To explore the adaptive response of the endocrine pancreas in vivo and in vitro and the possible beneficial effect of the insulino-mimetic agent vanadyl…”
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Age-dependent reduction in GLUT-2 levels is correlated with the impairment of the insulin secretory response in isolated islets of Sprague–Dawley rats by Novelli, M., De Tata, V., Bombara, M., Bergamini, E., Masiello, P.

“…In this study we have investigated the insulin secretory response to glucose and other secretagogues (2-ketoisocaproate, 3-isobutyl-1-methyl-xanthine and…”
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Endogenous Oxidative Stress Induces Distinct Redox Forms of Tumor Necrosis Factor Receptor-1 in Melanoma Cells by DOMINICI, S, PIERI, L, PAOLICCHI, A, DE TATA, V, ZUNINO, F, POMPELLA, A

“…: Receptors of the TNFR superfamily possess abundant thiols in their extracellular domains, which makes them susceptible to redox modulation by prooxidant…”
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Age-related changes in the urinary excretion of aldehydes in ad libitum fed and food-restricted rats by De Tata, V., Lorenzini, G., Cecchi, L., Ciuffi, C., Bergamini, E.

“…Age-related changes in the urinary excretion of aldehydes arising from lipid peroxidation have been investigated in male Sprague–Dawley rats aged 2, 4, 6, 12,…”
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Perfusate cytokines concentrations during liver grafts ex-situ normothermic perfusion (DCDNet Study) by Vacca, P.G., Pezzati, D., Bronzoni, J., Martinelli, C., Petruccelli, S., Carrai, P., Franzini, M., Balzano, E., Tincani, G., Catalano, G., Palladino, S., Masini, M., Rotondo, M.I., Babboni, S., Turco, S. Del, Morganti, R., Campani, D., De Tata, V., Biancofiore, G., Basta, G., Paolicchi, A., Ghinolfi, D.

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The induction of mitochondrial myopathy in the rat by feeding β-guanidinopropionic acid and the reversibility of the induced mitochondrial lesions : a biochemical and ultrastructural investigation by DE TATA, V, CAVALLINI, G, POLLERA, M, GORI, Z, BERGAMINI, E

“…The long-lasting depletions of creatine phosphate induced by feeding rats with a beta-guanidinopropionic acid (GPA)-supplemented diet induces specific…”
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Cell death and impairment of glucose-stimulated insulin secretion induced by 2,3,7,8-tetrachlorodibenzo- p-dioxin (TCDD) in the β-cell line INS-1E by Piaggi, Simona, Novelli, Michela, Martino, Luisa, Masini, Matilde, Raggi, Chiara, Orciuolo, Enrico, Masiello, Pellegrino, Casini, Alessandro, De Tata, Vincenzo

“…The aim of this research was to characterize 2,3,7,8-tetrachlorodibenzo- p-dioxin (TCDD) toxicity on the insulin-secreting β-cell line INS-1E. A sharp decline…”
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Regional differences in the response of cardiac cells to triiodothyronine administration across the left ventricle free wall of rat heart by DE TATA, V, GORI, Z, BERGAMINI, E

“…We have studied the effect of T3 administration (50 micrograms/Kg/day) on the phenotype expression of several glucose-metabolizing enzymes (hexokinase, HK,…”
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Determination of glycated hemoglobins in the rat: comparison between two different chromatographic methods and application in experimental diabetology by De Tata, V, Novelli, M, Bombara, M, Masiello, P, Cappuccio, A, Innocenti, B, Bergamini, E

“…Due to the unusual presence of several different hemoglobin components in the rat, determination of glycated hemoglobin (Hb) has been considered difficult and…”
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Changes in the transmural distribution of glucose-metabolizing enzymes across the left and right ventricular wall of rat heart during growth and ageing by De Tata, V, Gori, Z, Bergamini, E

“…The age-related changes in the activities of five glucose-metabolizing enzymes (hexokinase, HK; glucose-6-phosphate dehydrogenase, G6P-DH; aldolase, ALD;…”
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Changes in 5'-nucleotidase and adenosine deaminase distribution across the rat left ventricle wall during growth and aging by De Tata, V, Gori, Z, Bergamini, E

“…The concentrations of the adenosine-generating enzyme 5'-nucleotidase (5'-N) and of the adenosine-degrading enzyme adenosine deaminase (ADA) in the rat left…”
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Changes of glycogen metabolism in phosphorylcreatine-depleted muscles taken from rats fed with beta-guanidine propionate by De Tata, V, Gori Bergamini, Z, Bergamini, E

“…Changes in glycogen metabolism were explored in fast and slow muscles taken from rats fed with a diet containing 1% beta-guanidine propionate (GPA), a…”
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