Search Results - "De Souza Silva, Maria Angelica"
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Differential effects of D-cycloserine and amantadine on motor behavior and D2/3 receptor binding in the nigrostriatal and mesolimbic system of the adult rat
Published in Scientific reports (06-11-2019)“…D-cycloserine (DCS) and amantadine (AMA) act as partial NMDA receptor (R) agonist and antagonist, respectively. In the present study, we compared the effects…”
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2
Neuronal histamine and cognitive symptoms in Alzheimer's disease
Published in Neuropharmacology (01-07-2016)“…Alzheimer's disease is a neurodegenerative disorder characterized by extracellular amyloid plaque deposits, mainly composed of amyloid-beta peptide and…”
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3
Fellow travellers: Working memory and mental time travel in rodents
Published in Behavioural brain research (15-10-2018)“…The impairment of mental time travel is a severe cognitive symptom in patients with brain lesions and a number of neuropsychiatric disorders. Whether animals…”
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4
Intranasal administration of dopamine attenuates unconditioned fear in that it reduces restraint-induced ultrasound vocalizations and escape from bright light
Published in Journal of psychopharmacology (Oxford) (01-06-2017)“…Background: Although substantial evidence suggests that dopamine (DA) enhances conditioned fear responses, few studies have examined the role of DA in…”
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5
Amantadine enhances nigrostriatal and mesolimbic dopamine function in the rat brain in relation to motor and exploratory activity
Published in Pharmacology, biochemistry and behavior (01-04-2019)“…The present study assessed the influence of the NMDA receptor (R) antagonist amantadine (AMA) on cerebral dopamine D2/3R binding in relation to motor and…”
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6
Intra-nasal dopamine alleviates cognitive deficits in tgDISC1 rats which overexpress the human DISC1 gene
Published in Neurobiology of learning and memory (01-12-2017)“…•Rats with overexpressed human DISC1 gene show object attention deficits.•Rats with overexpressed human DISC1 gene show deficits in long-term object…”
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7
Levodopa ameliorates learning and memory deficits in a murine model of Alzheimer’s disease
Published in Neurobiology of aging (01-08-2009)“…Abstract Dopamine plays an important role in learning and memory processes. A deficit of this neurotransmitter as it is apparent in Alzheimer’s disease (AD)…”
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GABAergic control of neostriatal dopamine D 2 receptor binding and behaviors in the rat
Published in Pharmacology, biochemistry and behavior (01-02-2017)“…The present study assessed the influence of the GABA receptor agonist muscimol and the GABA receptor antagonist bicuculline on neostriatal dopamine D receptor…”
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9
Intranasal dopamine attenuates fear responses induced by electric shock to the foot and by electrical stimulation of the dorsal periaqueductal gray matter
Published in Journal of psychopharmacology (Oxford) (01-12-2019)“…Purpose: Intranasally applied dopamine (IN-DA), which likely reaches the brain via nasal–brain pathways and bypasses the blood–brain barrier, has been found to…”
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10
DAT versus D2 receptor binding in the rat striatum: l-DOPA-induced motor activity is better predicted by reuptake than release of dopamine
Published in Synapse (New York, N.Y.) (01-09-2016)“…ABSTRACT The reuptake and release of dopamine (DA) can be estimated using in vivo imaging methods by assessing the competition between endogenous DA and an…”
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11
Conditioned fear is modulated by D2 receptor pathway connecting the ventral tegmental area and basolateral amygdala
Published in Neurobiology of learning and memory (2011)“…Excitation of the mesocorticolimbic pathway, originating from dopaminergic neurons in the ventral tegmental area (VTA), may be important for the development of…”
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12
Unrestricted somatic stem cells from human umbilical cord blood can be differentiated into neurons with a dopaminergic phenotype
Published in Stem cells and development (01-04-2008)“…Recently, it has been shown that human unrestricted somatic stem cells (USSCs) from umbilical cord blood represent pluripotent, neonatal, nonhematopoietic stem…”
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13
Relationship between L-DOPA-induced reduction in motor and exploratory activity and degree of DAT binding in the rat
Published in Frontiers in behavioral neuroscience (17-12-2014)“…The present study assessed the influence of L-DOPA administration on neostriatal dopamine (DA) transporter (DAT) binding in relation to motor and exploratory…”
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Pharmacological challenge and synaptic response - assessing dopaminergic function in the rat striatum with small animal single-photon emission computed tomography (SPECT) and positron emission tomography (PET)
Published in Reviews in the neurosciences (01-12-2011)“…Disturbances of dopaminergic neurotransmission may be caused by changes in concentrations of synaptic dopamine (DA) and/or availabilities of pre- and…”
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15
Superior Water Maze Performance and Increase in Fear-Related Behavior in the Endothelial Nitric Oxide Synthase-Deficient Mouse Together with Monoamine Changes in Cerebellum and Ventral Striatum
Published in The Journal of neuroscience (01-09-2000)“…Nitric oxide (NO) has been implicated in the control of emotion, learning, and memory. We have examined endothelial NO synthase-deficient mice (eNOS-/-) in…”
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16
The relevance of neuronal substrates of defense in the midbrain tectum to anxiety and stress: empirical and conceptual considerations
Published in European journal of pharmacology (28-02-2003)“…The medial hypothalamus, amygdala, and dorsal periaqueductal gray constitute the main neural substrates for the integration of aversive states in the brain…”
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17
Anxiogenic-like behavior and deficient attention/working memory in rats expressing the human DISC1 gene
Published in Pharmacology, biochemistry and behavior (01-04-2019)“…In humans, mutations in the Disrupted-in-schizophrenia 1 (DISC1) gene have been related to psychiatric disorders, including symptoms of abnormal cognitive and…”
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18
GABAergic control of neostriatal dopamine D2 receptor binding and behaviors in the rat
Published in Pharmacology, biochemistry and behavior (01-02-2017)“…The present study assessed the influence of the GABAA receptor agonist muscimol and the GABAA receptor antagonist bicuculline on neostriatal dopamine D2…”
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Journal Article -
19
Differential effects of D-cycloserine and amantadine on motor behavior and D 2/3 receptor binding in the nigrostriatal and mesolimbic system of the adult rat
Published in Scientific reports (06-11-2019)“…D-cycloserine (DCS) and amantadine (AMA) act as partial NMDA receptor (R) agonist and antagonist, respectively. In the present study, we compared the effects…”
Get full text
Journal Article -
20
SHORT COMMUNICATIONS: Increases in extracellular levels of 5-HT and dopamine in the basolateral, but not in the central, nucleus of amygdala induced by aversive stimulation of the inferior colliculus
Published in The European journal of neuroscience (01-02-2005)“…Consistent evidence has shown that dopamine release in the prefrontal cortex is increased by electrical stimulation of the inferior colliculus (IC) as…”
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