Search Results - "De Souza, Gabriela F."
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Catalytic redox-neutral C-H functionalisation with TEMPO in water to access aminomethyl-substituted pyrroles
Published in Organic & biomolecular chemistry (04-05-2022)“…A redox-neutral C-H functionalisation in water employing catalytic TEMPO to synthesize aminomethyl-substituted pyrroles is reported. Starting from cheap and…”
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2
Vinpocetine reduces carrageenan-induced inflammatory hyperalgesia in mice by inhibiting oxidative stress, cytokine production and NF-κB activation in the paw and spinal cord
Published in PloS one (30-03-2015)“…Vinpocetine is a safe nootropic agent used for neurological and cerebrovascular diseases. The anti-inflammatory activity of vinpocetine has been shown in cell…”
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3
Respiratory Syncytial Virus induces the classical ROS-dependent NETosis through PAD-4 and necroptosis pathways activation
Published in Scientific reports (21-09-2018)“…Respiratory syncytial virus (RSV) is a major cause of diseases of the respiratory tract in young children and babies, being mainly associated with…”
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4
Visible-Light-Driven Epoxyacylation and Hydroacylation of Olefins Using Methylene Blue/Persulfate System in Water
Published in Journal of organic chemistry (03-08-2018)“…A visible-light-driven strategy for hydroacylation and epoxyacylation of olefins in water using methylene blue as photoredox catalyst and persulfate as oxidant…”
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Neutralisation of SARS-CoV-2 lineage P.1 by antibodies elicited through natural SARS-CoV-2 infection or vaccination with an inactivated SARS-CoV-2 vaccine: an immunological study
Published in The Lancet. Microbe (01-10-2021)“…Mutations accrued by SARS-CoV-2 lineage P.1—first detected in Brazil in early January, 2021—include amino acid changes in the receptor-binding domain of the…”
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Molecular Epidemiology of Mayaro Virus among Febrile Patients, Roraima State, Brazil, 2018-2021
Published in Emerging infectious diseases (01-05-2024)“…We detected Mayaro virus (MAYV) in 3.4% (28/822) of febrile patients tested during 2018-2021 from Roraima State, Brazil. We also isolated MAYV strains and…”
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S-nitroso-N-acetylcysteine attenuates liver fibrosis in cirrhotic rats
Published in Journal of molecular medicine (Berlin, Germany) (01-04-2010)“…This study was aimed to investigate the molecular mechanisms underlying prevention of hepatic fibrosis by S-nitroso-N-acetylcysteine (SNAC), a nitric oxide…”
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“On Water” Metal-Catalyst-Free Oxidative Coupling–Amidation of Amines To Access Imines and Amides
Published in ACS sustainable chemistry & engineering (05-09-2017)“…A simple route toward the selective synthesis of imines and amides through oxidative coupling–oxidative amidation of amines using widely available NaOCl is…”
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Topical Docosahexaenoic Acid (DHA) Accelerates Skin Wound Healing in Rats and Activates GPR120
Published in Biological research for nursing (01-07-2016)“…Background: The development of methods for improving skin wound healing may have an impact on the outcomes of a number of medical conditions. The topical use…”
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S-nitroso-N-acetylcysteine attenuates liver fibrosis in experimental nonalcoholic steatohepatitis
Published in Drug design, development and therapy (01-01-2013)“…S-Nitroso-N-acetylcysteine (SNAC) is a water soluble primary S-nitrosothiol capable of transferring and releasing nitric oxide and inducing several biochemical…”
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Topical 5-azacytidine accelerates skin wound healing in rats
Published in Wound repair and regeneration (01-09-2014)“…The development of new methods to improve skin wound healing may affect the outcomes of a number of medical conditions. Here, we evaluate the molecular and…”
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Nitric oxide released from luminal s-nitroso-N-acetylcysteine increases gastric mucosal blood flow
Published in Molecules (Basel, Switzerland) (04-03-2015)“…Nitric oxide (NO)-mediated vasodilation plays a key role in gastric mucosal defense, and NO-donor drugs may protect against diseases associated with gastric…”
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Antithrombogenic Polynitrosated Polyester/Poly(methyl methacrylate) Blend for the Coating of Blood-Contacting Surfaces
Published in Artificial organs (01-04-2008)“…: A nitric oxide (NO) donor polyester containing multiple S‐nitrosothiol (S‐NO) groups covalently attached to the polymer backbone was synthesized through the…”
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(-)-Tarchonanthuslactone exerts a blood glucose-increasing effect in experimental type 2 diabetes mellitus
Published in Molecules (Basel, Switzerland) (19-03-2015)“…A number of studies have proposed an anti-diabetic effect for tarchonanthuslactone based on its structural similarity with caffeic acid, a compound known for…”
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Enhanced performance of impedimetric immunosensors to detect SARS-CoV-2 with bare gold nanoparticles and graphene acetic acid
Published in Talanta (Oxford) (01-01-2025)“…Immunosensors based on electrical impedance spectroscopy allow for label-free, real-time detection of biologically relevant molecules and pathogens, without…”
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Macrophage migration inhibitory factor (MIF) controls cytokine release during respiratory syncytial virus infection in macrophages
Published in Inflammation research (01-06-2019)“…Objective and design Respiratory syncytial virus (RSV) is the major cause of infection in children up to 2 years old and reinfection is very common among…”
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S-nitrosoglutathione inhibits inducible nitric oxide synthase upregulation by redox posttranslational modification in experimental diabetic retinopathy
Published in Investigative ophthalmology & visual science (02-05-2014)“…Diabetic retinopathy (DR) is associated with nitrosative stress. The purpose of this study was to evaluate the beneficial effects of S-nitrosoglutathione…”
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Acetic acid- and phenyl-p-benzoquinone-induced overt pain-like behavior depends on spinal activation of MAP kinases, PI3K and microglia in mice
Published in Pharmacology, biochemistry and behavior (01-05-2012)“…The acetic acid and phenyl-p-benzoquinone are easy and fast screening models to access the activity of novel candidates as analgesic drugs and their…”
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In vitro inhibition of linoleic acid peroxidation by primary S-nitrosothiols
Published in Journal of the Brazilian Chemical Society (2010)“…Nitric oxide (•NO) is an effective chain-breaking antioxidant in the inhibition of lipid peroxidation and circulates in vivo mainly as primary S-nitrosothiols…”
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Morphological, cellular, and molecular basis of brain infection in COVID-19 patients
Published in Proceedings of the National Academy of Sciences - PNAS (30-08-2022)“…Although increasing evidence confirms neuropsychiatric manifestations associated mainly with severe COVID-19 infection, long-term neuropsychiatric dysfunction…”
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