Search Results - "De Souza, Daniel C"
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Ionophore-mediated swelling of erythrocytes as a therapeutic mechanism in sickle cell disease
Published in Haematologica (Roma) (01-06-2022)“…Sickle cell disease (SCD) is characterized by sickle hemoglobin (HbS) which polymerizes under deoxygenated conditions to form a stiff, sickled erythrocyte. The…”
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Journal Article -
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Genetic reversal of the globin switch concurrently modulates both fetal and sickle hemoglobin and reduces red cell sickling
Published in Nature communications (20-09-2023)“…We previously reported initial clinical results of post-transcriptional gene silencing of BCL11A expression (NCT 03282656) reversing the fetal to adult…”
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Journal Article -
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Effects of High-Intensity Interval and Moderate-Intensity Continuous Exercise on Inflammatory, Leptin, IgA, and Lipid Peroxidation Responses in Obese Males
Published in Frontiers in physiology (23-05-2018)“…To compare the effects of a single high-intensity interval exercise session (HIIE) with a moderate-intensity continuous exercise session (MICE) on the…”
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Development of Disposable and Flexible Supercapacitor Based on Carbonaceous and Ecofriendly Materials
Published in C (Basel) (01-06-2022)“…A novel flexible supercapacitor device was developed from a polyethylene terephthalate substrate, reused from beverage bottles, and a conductive ink based on…”
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Journal Article -
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Response of an oscillatory differential delay equation to a periodic stimulus
Published in Journal of mathematical biology (01-05-2019)“…Periodic hematological diseases such as cyclical neutropenia or cyclical thrombocytopenia, with their characteristic oscillations of circulating neutrophils or…”
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Journal Article -
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Effects of BCL11A Shmir-Induced Post-Transcriptional Silencing on Hemoglobin Polymer Inhibition in Single Red Blood Cells at Physiologic Oxygen Tension
Published in Blood (23-11-2021)“…Introduction Fetal hemoglobin (HbF) induction is a successful strategy for treating sickle cell disease. Higher levels of total HbF% are associated with better…”
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Journal Article -
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Dynamics of a Mathematical Hematopoietic Stem-Cell Population Model
Published 11-01-2019“…Journal on Applied Dynamical Systems, 18 (2019), 808-852 We explore the bifurcations and dynamics of a scalar differential equation with a single constant…”
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Journal Article -
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Response of an oscillatory delay differential equation to a periodic stimulus
Published 20-09-2018“…Periodic hematological diseases such as cyclical neutropenia or cyclical thrombocytopenia, with their characteristic oscillations of circulating neutrophils or…”
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Journal Article -
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On relevant quality criteria for optimized partitioning methods
Published in 2003 46th Midwest Symposium on Circuits and Systems (2003)“…This paper deals with HW/SW partitioning methods. The authors employed the concepts of "quality requisites" and a method based on QFD (quality function…”
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Conference Proceeding -
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Supporting Adaptive Virtual Environments with Intelligent Agents
Published in Seventh International Conference on Intelligent Systems Design and Applications (ISDA 2007) (01-10-2007)“…Adaptive virtual environments have been developed aiming at generating 3D environments adapted to user's necessities and interests. Navigation aid techniques…”
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Conference Proceeding