Search Results - "De Sousa, Dorothy"
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Effects of combined tiotropium/olodaterol on inspiratory capacity and exercise endurance in COPD
Published in The European respiratory journal (01-04-2017)“…Two replicate, double-blind, 6-week, incomplete-crossover studies (MORACTO 1 and 2) assessed the effects of tiotropium/olodaterol on inspiratory capacity and…”
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Journal Article -
2
Effect of Bronchodilation, Exercise Training, and Behavior Modification on Symptoms and Physical Activity in Chronic Obstructive Pulmonary Disease
Published in American journal of respiratory and critical care medicine (15-10-2018)“…Bronchodilation and exercise training (ExT) improve exercise tolerance in patients with chronic obstructive pulmonary disease (COPD); however, behavior…”
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3
RORγt inhibitors block both IL-17 and IL-22 conferring a potential advantage over anti-IL-17 alone to treat severe asthma
Published in Respiratory research (22-05-2021)“…RORγt is a transcription factor that enables elaboration of Th17-associated cytokines (including IL-17 and IL-22) and is proposed as a pharmacological target…”
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Enhancing exercise tolerance and physical activity in COPD with combined pharmacological and non-pharmacological interventions: PHYSACTO randomised, placebo-controlled study design
Published in BMJ open (13-04-2016)“…IntroductionChronic obstructive pulmonary disease (COPD) is associated with exercise limitation and physical inactivity, which are believed to have significant…”
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Behaviour-change intervention in a multicentre, randomised, placebo-controlled COPD study: methodological considerations and implementation
Published in BMJ open (04-04-2016)“…IntroductionChronic obstructive pulmonary disease is generally progressive and associated with reduced physical activity. Both pharmacological therapy and…”
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Behavioural interventions targeting physical activity improve psychocognitive outcomes in COPD
Published in ERJ open research (01-10-2019)“…This study explored the impact of a self-management behaviour modification (SMBM) programme with/without bronchodilators and with/without exercise training…”
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Mechanisms associated with increased physical activity in patients undergoing self-management behaviour modification in the randomised PHYSACTO trial
Published in ERJ open research (01-01-2021)“…In this analysis of the PHYSACTO® study, we assessed the efficacy of a self-management behaviour modification (SMBM) programme to improve physical activity…”
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Evaluation of the Effects of Olodaterol on Exercise Endurance in Patients With COPD: Results From Two 6-Week Studies
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Conference Proceeding -
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ROR[gamma]t inhibitors block both IL-17 and IL-22 conferring a potential advantage over anti-IL-17 alone to treat severe asthma
Published in Respiratory research (22-05-2021)“…Background ROR[gamma]t is a transcription factor that enables elaboration of Th17-associated cytokines (including IL-17 and IL-22) and is proposed as a…”
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Journal Article -
10
Evaluation of the effects of olodaterol on exercise endurance in patients with chronic obstructive pulmonary disease: results from two 6-week crossover studies
Published in Respiratory research (06-07-2016)“…Two replicate, double-blind, placebo-controlled, 6-week crossover studies assessed the effect of the once-daily long-acting β2-agonist olodaterol 5 μg and…”
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Journal Article