Search Results - "De Smedt, Renate"

Direct and indirect anti-leukemic properties of activity-on-target interferons for the treatment of T-cell acute lymphoblastic leukemia by Goossens, Steven, Cauwels, Anje, Pieters, Tim, De Smedt, Renate, T'Sas, Sara, Almeida, André, Daneels, Willem, Van Vlierberghe, Pieter, Tavernier, Jan

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Targeting hyperactive platelet-derived growth factor receptor-β signaling in T-cell acute lymphoblastic leukemia and lymphoma by De Coninck, Stien, De Smedt, Renate, Lintermans, Beatrice, Reunes, Lindy, Kosasih, Hansen J, Reekmans, Alexandra, Brown, Lauren M, Van Roy, Nadine, Palhais, Bruno, Roels, Juliette, Van der Linden, Malaika, Van Dorpe, Jo, Ntziachristos, Panagiotis, Van Delft, Frederik W, Mansour, Marc R, Pieters, Tim, Lammens, Tim, De Moerloose, Barbara, De Bock, Charles E, Goossens, Steven, Van Vlierberghe, Pieter

“…T-cell acute lymphoblastic leukemia (T-ALL) and T-cell lymphoblastic lymphoma (T-LBL) are rare aggressive hematologic malignancies. Current treatment consists…”
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Pre-clinical evaluation of second generation PIM inhibitors for the treatment of T-cell acute lymphoblastic leukemia and lymphoma by De Smedt, Renate, Peirs, Sofie, Morscio, Julie, Matthijssens, Filip, Roels, Juliette, Reunes, Lindy, Lintermans, Beatrice, Goossens, Steven, Lammens, Tim, Van Roy, Nadine, Touzart, Aurore, Jenni, Silvia, Tsai, Yi-Chien, Lovisa, Federica, Mussolin, Lara, Serafin, Valentina, Van Nieuwerburgh, Filip, Deforce, Dieter, Uyttebroeck, Anne, Tousseyn, Thomas, Burkhardt, Birgit, Klapper, Wolfram, De Moerloose, Barbara, Benoit, Yves, Macintyre, Elizabeth, Bourquin, Jean-Pierre, Basso, Giuseppe, Accordi, Benedetta, Bornhauser, Beat, Meijerink, Jules, Vandenberghe, Peter, Van Vlierberghe, Pieter

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Targeting steroid resistance in T-cell acute lymphoblastic leukemia by De Smedt, Renate, Morscio, Julie, Goossens, Steven, Van Vlierberghe, Pieter

“…T-cell acute lymphoblastic leukemia (T-ALL) is characterized by a variable response to steroids during induction and/or consolidation therapy. Notably, recent…”
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PDGFR-β As a New Therapeutic Target in T-Cell Acute Lymphoblastic Leukemia by De Coninck, Stien, De Smedt, Renate, Lintermans, Beatrice, Goossens, Steven, Van Vlierberghe, Pieter

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3066 – TARGETING HYPERACTIVE PLATELET DERIVED GROWTH FACTOR RECEPTOR BETA IN T CELL ACUTE LYMPHOBLASTIC LEUKEMIA AND T CELL LYMPHOBLASTIC LYMPHOMA by De Coninck, Stien, De Smedt, Renate, Lintermans, Béatrice, Goossens, Steven, Van Vlierberghe, Pieter

“…Platelet derived growth factor β (PDGFR-β) is a transmembrane glycoprotein dimer molecule that functions as a receptor tyrosine kinase. Ligand binding results…”
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Targeting cytokine- and therapy-induced PIM1 activation in preclinical models of T-cell acute lymphoblastic leukemia and lymphoma by De Smedt, Renate, Morscio, Julie, Reunes, Lindy, Roels, Juliette, Bardelli, Valentina, Lintermans, Beatrice, Van Loocke, Wouter, Almeida, Afonso, Cheung, Laurence C., Kotecha, Rishi S., Mansour, Marc R., Uyttebroeck, Anne, Vandenberghe, Peter, La Starza, Roberta, Mecucci, Cristina, Lammens, Tim, Van Roy, Nadine, De Moerloose, Barbara, Barata, João T., Taghon, Tom, Goossens, Steven, Van Vlierberghe, Pieter

“…T-cell acute lymphoblastic leukemia (T-ALL) and T-cell acute lymphoblastic lymphoma (T-LBL) are aggressive hematological malignancies that are currently…”
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Genetic Activation and Therapeutic Targeting of PIM1 in T-Cell Acute Lymphoblastic Leukemia/Lymphoma by De Smedt, Renate, Peirs, Sofie, Morscio, Julie, Roels, Juliette, Goossens, Steven, Touzart, Aurore, Uyttebroeck, Anne, Van Roy, Nadine, Lammens, Tim, Mussolin, Lara, Macyntire, Elizabeth, Vandenberghe, Peter, Van Vlierberghe, Pieter

“…T-cell acute lymphoblastic leukemia (T-ALL) and T-cell acute lymphoblastic lymphoma (T-LBL) are aggressive immature T-cell malignancies that are often…”
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Pre-Clinical Evaluation of the Hypomethylating Agent Decitabine for the Treatment of T-Cell Lymphoblastic Lymphoma by Provez, Lien, Putteman, Tom, Landfors, Mattias, Roels, Juliette, Reunes, Lindy, T'Sas, Sara, Van Loocke, Wouter, Lintermans, Béatrice, De Coninck, Stien, Thenoz, Morgan, Sleeckx, Wouter, Maćkowska-Maślak, Natalia, Taghon, Tom, Mansour, Marc R, Farah, Nadine, Norga, Koen, Vandenberghe, Peter, Kotecha, Rishi S, Goossens, Steven, Degerman, Sofie, De Smedt, Renate, Van Vlierberghe, Pieter

“…T-cell lymphoblastic lymphoma (T-LBL) is a rare and aggressive lymphatic cancer, often diagnosed at a young age. Patients are treated with intensive…”
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