Search Results - "De Silva, N. M. G."

Multiple genetic variants explain measurable variance in type 2 diabetes-related traits in Pakistanis by Islam, M., Jafar, T. H., Wood, A. R., De Silva, N. M. G., Caulfield, M., Chaturvedi, N., Frayling, T. M.

“…Aims/hypothesis Multiple genetic variants are associated with type 2 diabetes-related traits in Europeans, but their role in South Asian populations needs…”
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The transcription factor 7-like 2 (TCF7L2) gene is associated with Type 2 diabetes in UK community-based cases, but the risk allele frequency is reduced compared with UK cases selected for genetic studies by De Silva, N. M. G., Steele, A., Shields, B., Knight, B., Parnell, K., Weedon, M. N., Hattersley, A. T., Frayling, T. M.

“…Aims  Common polymorphisms in the transcription factor 7‐like 2 (TCF7L2) gene are strongly associated with Type 2 diabetes. Many studies include a large…”
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