Search Results - "De Santis, Emiliana"

Interfacial zippering-up of coiled-coil protein filaments by Santis, Emiliana De, Castelletto, Valeria, Ryadnov, Maxim G

“…Protein self-assembled materials find increasing use in medicine and nanotechnology. A challenge remains in our ability to tailor such materials at a given…”
Get more information

Peptide self-assembly for nanomaterials: the old new kid on the block by De Santis, Emiliana, Ryadnov, Maxim G

“…Peptide self-assembly is an increasingly attractive tool for nanomaterials. Perfected in biology peptide self-assembling systems have impacted on nearly any…”
Get more information

Antimicrobial peptide capsids of de novo design by De Santis, Emiliana, Alkassem, Hasan, Lamarre, Baptiste, Faruqui, Nilofar, Bella, Angelo, Noble, James E., Micale, Nicola, Ray, Santanu, Burns, Jonathan R., Yon, Alexander R., Hoogenboom, Bart W., Ryadnov, Maxim G.

“…The spread of bacterial resistance to antibiotics poses the need for antimicrobial discovery. With traditional search paradigms being exhausted, approaches…”
Get full text

Imaging Protein Fibers at the Nanoscale and In Situ by Bella, Angelo, Shaw, Michael, De Santis, Emiliana, Ryadnov, Maxim G

“…Protein self-assembly offers a rich repertoire of tools and technologies. However, despite significant progress in this area, a deterministic measure of the…”
Get more information

Deagglomeration of DNA nanomedicine carriers using controlled ultrasonication by Hinchliffe, Beth A., Turner, Piers, J. H. Cant, David, De Santis, Emiliana, Aggarwal, Purnank, Harris, Rob, Templeton, David, Shard, Alex G., Hodnett, Mark, Minelli, Caterina

“…[Display omitted] •Controlled inertial cavitation produced reproducible particle deagglomeration.•The inertial cavitation dose did not affect the spiky…”
Get full text

Quality assessment of virus-like particle: A new transmission electron microscopy approach by De Sá Magalhães, Salomé, De Santis, Emiliana, Hussein-Gore, Saba, Colomb-Delsuc, Mathieu, Keshavarz-Moore, Eli

“…Transmission electron microscopy (TEM) is a gold standard analytical method for nanoparticle characterization and is playing a valuable role in virus-like…”
Get full text

High-performance liquid chromatography enantioseparation of proton pump inhibitors using the immobilized amylose-based Chiralpak IA chiral stationary phase in normal-phase, polar organic and reversed-phase conditions by Cirilli, Roberto, Ferretti, Rosella, Gallinella, Bruno, De Santis, Emiliana, Zanitti, Leo, La Torre, Francesco

“…The chiral resolving ability of the amylose-based Chiralpak IA chiral stationary phase towards omeprazole and other proton pump inhibitors under reversed-phase…”
Get full text

The effect of palmitoylation on the conformation and physical stability of a model peptide hormone by Longo, Edoardo, Santis, Emiliana De, Hussain, Rohanah, van der Walle, Christopher F., Casas-Finet, Jose, Uddin, Shahid, Santos, Ana Dos, Siligardi, Giuliano

“…[Display omitted] Peptides are ideal drug candidates due to their potency and specificity, but suffer from a short half-life and low membrane permeability…”
Get full text

Imaging and 3D Reconstruction of De Novo Peptide Capsids by De Santis, Emiliana, Ryadnov, Maxim G

“…Nanoscale systems encapsulating biomacromolecules hold promise for cell and gene therapies. Common issues hampering progress include polydispersity,…”
Get more information

Engineering Chirally Blind Protein Pseudocapsids into Antibacterial Persisters by Kepiro, Ibolya E, Marzuoli, Irene, Hammond, Katharine, Ba, Xiaoliang, Lewis, Helen, Shaw, Michael, Gunnoo, Smita B, De Santis, Emiliana, Łapińska, Urszula, Pagliara, Stefano, Holmes, Mark A, Lorenz, Christian D, Hoogenboom, Bart W, Fraternali, Franca, Ryadnov, Maxim G

“…Antimicrobial resistance stimulates the search for antimicrobial forms that may be less subject to acquired resistance. Here we report a conceptual design of…”
Get full text

A Nonlinear Peptide Topology for Synthetic Virions by Noble, James E., Hsiao, Ya-Wen, Kepiro, Ibolya E., De Santis, Emiliana, Hoose, Alex, Augagneur, Celine, Lamarre, Baptiste, Briones, Andrea, Hammond, Katharine, Bray, David J., Crain, Jason, Ryadnov, Maxim G.

“…a nonlinear de novo peptide topology for the assembly of synthetic virions is reported. The topology is a backbone cyclized amino-acid sequence in which polar…”
Get full text

Hyperspectral Mapping of Human Primary and Stem Cells at Cell–Matrix Interfaces by De Santis, Emiliana, Faruqui, Nilofar, Russell, Craig T., Noble, James E., Kepiro, Ibolya E., Hammond, Katharine, Tsalenchuk, Maria, Ryadnov, Eugeni M., Wolna, Magda, Frogley, Mark D., Price, Christopher J., Barbaric, Ivana, Cinque, Gianfelice, Ryadnov, Maxim G.

“…Extracellular matrices interface with cells to promote cell growth and tissue development. Given this critical role, matrix mimetics are introduced to enable…”
Get full text

Structurally plastic peptide capsules for synthetic antimicrobial viruses by Castelletto, Valeria, de Santis, Emiliana, Alkassem, Hasan, Lamarre, Baptiste, Noble, James E, Ray, Santanu, Bella, Angelo, Burns, Jonathan R, Hoogenboom, Bart W, Ryadnov, Maxim G

“…A conceptual design for artificial antimicrobial viruses is described. The design emulates viral assembly and function to create self-assembling peptide…”
Get full text

Exploitable length correlations in peptide nanofibres by De Santis, Emiliana, Faruqui, Nilofar, Noble, James E, Ryadnov, Maxim G

“…Sequence-prescribed biomolecular assemblies find increasing use in the development of novel nanostructured materials. Critical requirements for emerging…”
Get more information

A De Novo Virus-Like Topology for Synthetic Virions by Noble, James E, De Santis, Emiliana, Ravi, Jascindra, Lamarre, Baptiste, Castelletto, Valeria, Mantell, Judith, Ray, Santanu, Ryadnov, Maxim G

“…A de novo topology of virus-like assembly is reported. The design is a trifaceted coiled-coil peptide helix, which self-assembles into ultrasmall,…”
Get full text

Convenient Solution-Phase Synthesis and Conformational Studies of Novel Linear and Cyclic α,β-Alternating Peptoids by Hjelmgaard, Thomas, Faure, Sophie, Caumes, Cécile, De Santis, Emiliana, Edwards, Alison A, Taillefumier, Claude

“…The synthesis of a novel family of peptidomimetics composed of linear and cyclic α,β-alternating peptoids is described. Oligomers consisting of up to six…”
Get full text

Autonomously folded α-helical lockers promote RNAi by Guyader, Christian P. E., Lamarre, Baptiste, De Santis, Emiliana, Noble, James E., Slater, Nigel K., Ryadnov, Maxim G.

“…RNAi is an indispensable research tool with a substantial therapeutic potential. However, the complete transition of the approach to an applied capability…”
Get full text

Structurally plastic peptide capsules for synthetic antimicrobial virusesElectronic supplementary information (ESI) available: Materials and methods, microscopy, spectroscopy, electrophoretic and X-ray scattering data. See DOI: 10.1039/c5sc03260a by Castelletto, Valeria, de Santis, Emiliana, Alkassem, Hasan, Lamarre, Baptiste, Noble, James E, Ray, Santanu, Bella, Angelo, Burns, Jonathan R, Hoogenboom, Bart W, Ryadnov, Maxim G

“…A conceptual design for artificial antimicrobial viruses is described. The design emulates viral assembly and function to create self-assembling peptide…”
Get full text

Structurally plastic peptide capsules for synthetic antimicrobial viruses† †Electronic supplementary information (ESI) available: Materials and methods, microscopy, spectroscopy, electrophoretic and X-ray scattering data. See DOI: 10.1039/c5sc03260a Click here for additional data file. Click here for additional data file by Castelletto, Valeria, de Santis, Emiliana, Alkassem, Hasan, Lamarre, Baptiste, Noble, James E., Ray, Santanu, Bella, Angelo, Burns, Jonathan R., Hoogenboom, Bart W., Ryadnov, Maxim G.

“…A conceptual design for artificial antimicrobial viruses is described. A conceptual design for artificial antimicrobial viruses is described. The design…”
Get full text

Improved solid-phase synthesis and study of arylopeptoids with conformation-directing side chains by Hjelmgaard, Thomas, Faure, Sophie, De Santis, Emiliana, Staerk, Dan, Alexander, Bruce D., Edwards, Alison A., Taillefumier, Claude, Nielsen, John

“…The development of an improved methodology for iterative solid-phase synthesis of para- and meta-arylopeptoids (oligomeric N-substituted aminomethyl…”
Get full text