Search Results - "De Sá Lima, Larissa"

Klotho deficiency aggravates sepsis-related multiple organ dysfunction by Jorge, Lectícia B, Coelho, Fernanda O, Sanches, Talita R, Malheiros, Denise M A C, Ezaquiel de Souza, Leandro, Dos Santos, Fernando, de Sá Lima, Larissa, Scavone, Cristóforo, Irigoyen, Maria, Kuro-O, Makoto, Andrade, Lucia

“…Sepsis-induced organ failure is characterized by a massive inflammatory response and oxidative stress. Acute kidney injury (AKI) occurs in approximately half…”
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Altered KLOTHO and NF-κB-TNF-α Signaling Are Correlated with Nephrectomy-Induced Cognitive Impairment in Rats by Degaspari, Sabrina, Tzanno-Martins, Carmen Branco, Fujihara, Clarice Kazue, Zatz, Roberto, Branco-Martins, João Paulo, Viel, Tania Araujo, Buck, Hudson de Souza, Orellana, Ana Maria Marques, Böhmer, Ana Elisa, Lima, Larissa de Sá, Andreotti, Diana Zukas, Munhoz, Carolina Demarchi, Scavone, Cristoforo, Kawamoto, Elisa Mitiko

“…Renal insufficiency can have a negative impact on cognitive function. Neuroinflammation and changes in klotho levels associate with chronic kidney disease…”
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Effects of isoproterenol treatment for 7 days on inflammatory mediators in the rat aorta by Davel, Ana Paula C, Fukuda, Livia E, De Sá, Larissa Lima, Munhoz, Carolina D, Scavone, Cristoforo, Sanz-Rosa, David, Cachofeiro, Victoria, Lahera, Vicente, Rossoni, Luciana V

“…The aim of the present study was to evaluate the effect of overstimulation of beta-adrenoceptors on vascular inflammatory mediators. Wistar rats were treated…”
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Age-related neuroinflammation and changes in AKT-GSK-3β and WNT/ β-CATENIN signaling in rat hippocampus by Orellana, Ana Maria Marques, Vasconcelos, Andrea Rodrigues, Leite, Jacqueline Alves, de Sá Lima, Larissa, Andreotti, Diana Zukas, Munhoz, Carolina Demarchi, Kawamoto, Elisa Mitiko, Scavone, Cristoforo

“…Aging is a multifactorial process associated with an increased susceptibility to neurodegenerative disorders which can be related to chronic inflammation…”
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Neuroprotective action of α-Klotho against LPS-activated glia conditioned medium in primary neuronal culture by Nakao, Vinicius Wanatable, Mazucanti, Caio Henrique Yokowama, de Sá Lima, Larissa, de Mello, Paloma Segura, de Souza Port’s, Natacha Medeiros, Kinoshita, Paula Fernanda, Leite, Jacqueline Alves, Kawamoto, Elisa Mitiko, Scavone, Cristoforo

“…The α-Klotho is an anti-aging protein that, when overexpressed, extends the life span in humans and mice. It has an anti-inflammatory and protective action on…”
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Immunomodulatory response in an experimental model of brain death by Santana, Alexandre Chagas, Andraus, Wellington, Zimelewicz Oberman, Dan, Rabelo, Nícollas Nunes, Silva, Filipe Miranda Oliveira, Dellê, Humberto, Pepineli, Rafael, de Moraes, Edvaldo Leal, Scavone, Cristoforo, de Sá Lima, Larissa, Degaspari, Sabrina, Brasil, Sérgio, Solla, Davi Jorge Fontoura, Ruiz, Liliane Moreira, de Oliveira-Braga, Karina Andrighetti, Nepomuceno, Natalia Aparecida, Pêgo-Fernandes, Paulo Manuel, Tullius, Stefan Gunther, Figueiredo, Eberval Gadelha

“…Liver transplantation has come a long way and is now regarded as the gold standard treatment for end-stage liver failure. The great majority of livers utilized…”
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Chronic Unpredictable Stress Exacerbates Lipopolysaccharide-Induced Activation of Nuclear Factor-κB in the Frontal Cortex and Hippocampus via Glucocorticoid Secretion by Munhoz, Carolina Demarchi, Lepsch, Lucilia B., Kawamoto, Elisa Mitiko, Malta, Marília Brinati, Lima, Larissa de Sá, Werneck Avellar, Maria Christina, Sapolsky, Robert M., Scavone, Cristoforo

“…Although the anti-inflammatory actions of glucocorticoids (GCs) are well established in the periphery, these stress hormones can increase inflammation under…”
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Effects of intermittent fasting on age-related changes on Na,K-ATPase activity and oxidative status induced by lipopolysaccharide in rat hippocampus by Vasconcelos, Andrea Rodrigues, Kinoshita, Paula Fernanda, Yshii, Lidia Mitiko, Marques Orellana, Ana Maria, Böhmer, Ana Elisa, de Sá Lima, Larissa, Alves, Rosana, Andreotti, Diana Zukas, Marcourakis, Tania, Scavone, Cristoforo, Kawamoto, Elisa Mitiko

“…Abstract Chronic neuroinflammation is a common characteristic of neurodegenerative diseases, and lipopolysaccharide (LPS) signaling is linked to…”
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Alpha 2 Na+,K+-ATPase silencing induces loss of inflammatory response and ouabain protection in glial cells by Kinoshita, Paula F., Yshii, Lidia M., Orellana, Ana Maria M., Paixão, Amanda G., Vasconcelos, Andrea R., Lima, Larissa de Sá, Kawamoto, Elisa M., Scavone, Cristoforo

“…Ouabain (OUA) is a cardiac glycoside that binds to Na + ,K + -ATPase (NKA), a conserved membrane protein that controls cell transmembrane ionic concentrations…”
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Immunomodulatory effects of thalidomide in an experimental brain death liver donor model by Santana, Alexandre Chagas, Andraus, Wellington, Silva, Filipe Miranda Oliveira, Dellê, Humberto, Pepineli, Rafael, de Moraes, Edvaldo Leal, Scavone, Cristoforo, de Sá Lima, Larissa, Degaspari, Sabrina, Brasil, Sergio, Solla, Davi Jorge Fontoura, Ruiz, Liliane Moreira, de Oliveira-Braga, Karina Andrighetti, Nepomuceno, Natalia Aparecida, Pêgo-Fernandes, Paulo Manuel, Tullius, Stefan Gunther, Figueiredo, Eberval Gadelha

“…Brain death is characterized by a generalized inflammatory response that results in multiorgan damage. This process is mainly mediated through cytokines, which…”
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Sex-dependent changes in AMPAR expression and Na, K-ATPase activity in the cerebellum and hippocampus of α-Klotho-Hypomorphic mice by dos Santos, Geovana Rosa Oliveira, Cararo-Lopes, Marina Minto, Possebom, Isabela Ribeiro, de Sá Lima, Larissa, Scavone, Cristoforo, Kawamoto, Elisa Mitiko

“…Aging is characterized by a functional decline in several physiological systems. α-Klotho-hypomorphic mice (Kl−/−) exhibit accelerated aging and cognitive…”
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Strategies for the evaluation of the eye irritation potential of different types of surfactants and silicones used in cosmetic products by Sá, Larissa de Lima, Rodrigues, Rodrigo Vieira, Alves, Vani M., Gaspar, Lorena Rigo

“…The ocular irritation potential of products that may come into contact with the eyes should be assessed by the combination of different in vitro alternative…”
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Ouabain increases neuronal branching in hippocampus and improves spatial memory by Orellana, Ana Maria, Leite, Jacqueline Alves, Kinoshita, Paula Fernanda, Vasconcelos, Andrea Rodrigues, Andreotti, Diana Zukas, de Sá Lima, Larissa, Xavier, Gilberto Fernando, Kawamoto, Elisa Mitiko, Scavone, Cristoforo

“…Previous research shows Ouabain (OUA) to bind Na, K-ATPase, thereby triggering a number of signaling pathways, including the transcription factors NFᴋB and…”
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Klotho increases antioxidant defenses in astrocytes and ubiquitin–proteasome activity in neurons by Orellana, Ana Maria, Mazucanti, Caio Henrique, dos Anjos, Leticia Pavan, de Sá Lima, Larissa, Kawamoto, Elisa Mitiko, Scavone, Cristoforo

“…Klotho is an antiaging protein, and its levels decline with age and chronic stress. The exogenous administration of Klotho can enhance cognitive performance in…”
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Thalidomide suppresses inflammation in adenine-induced CKD with uraemia in mice by Santana, Alexandre C, Degaspari, Sabrina, Catanozi, Sergio, Dellê, Humberto, de Sá Lima, Larissa, Silva, Cleonice, Blanco, Paula, Solez, Kim, Scavone, Cristoforo, Noronha, Irene L

“…Persistent systemic inflammation has been widely recognized in patients with chronic kidney disease (CKD), and is associated with increased risk of morbidity…”
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Signaling function of Na,K-ATPase induced by ouabain against LPS as an inflammation model in hippocampus by Kinoshita, Paula Fernanda, Yshii, Lidia Mitiko, Vasconcelos, Andrea Rodrigues, Orellana, Ana Maria Marques, Lima, Larissa de Sá, Davel, Ana Paula Couto, Rossoni, Luciana Venturini, Kawamoto, Elisa Mitiko, Scavone, Cristoforo

“…Ouabain (OUA) is a newly recognized hormone that is synthesized in the adrenal cortex and hypothalamus. Low doses of OUA can activate a signaling pathway by…”
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Apocynin and Nox2 regulate NF-κB by modifying thioredoxin-1 redox-state by Trevelin, Silvia Cellone, dos Santos, Célio Xavier, Ferreira, Raphael Gomes, de Sá Lima, Larissa, Silva, Rangel Leal, Scavone, Cristoforo, Curi, Rui, Alves-Filho, José Carlos, Cunha, Thiago Mattar, Roxo-Júnior, Pérsio, Cervi, Maria-Célia, Laurindo, Francisco Rafael Martins, Hothersall, John Stephen, Cobb, Andrew M., Zhang, Min, Ivetic, Aleksandar, Shah, Ajay M., Lopes, Lucia Rossetti, Cunha, Fernando Queiroz

“…The reactive-oxygen-species-(ROS)-generating-enzyme Nox2 is essential for leukocyte anti-microbial activity. However its role in cellular redox homeostasis…”
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EVALUATION OF BDNF AND TRKB RECEPTOR EXPRESSION IN LUNG AND BRAIN OF FEMALE MICE SUBMITTED TO MIXED ASTHMA by Ribeiro, Martina, Nachbar, Julia, Oliveira, Maria, Siena, Amanda, Melhado, Isabela, Alves, Victoria, Lima, Thiago, Moriya, Henrique, De Sá Lima, Larissa, Orellana, Ana, Oliveira-Filho, Ricardo, Tavares-De-Lima, Wothan, Scavone, Cristoforo

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Long-term cyclosporine A treatment promotes anxiety-like behavior: Possible relation with glutamate signaling in rat hippocampus by Cararo-Lopes, Marina Minto, Souza, Débora Guerini, Ganzella, Marcelo, Hansel, Gisele, Kazlauckas, Vanessa, De Mello, Paloma Segura, Lima, Larissa De Sá, Kawamoto, Elisa Mitiko, Portela, Luis Valmor, Souza, Diogo Onofre, Scavone, Cristoforo, Böhmer, Ana Elisa

“…•Long-term CsA treatment induces anxiety-like behavior.•Hippocampus of CsA-treated rats presents increased GluN2 levels, NOS and CREB activities.•Chronic CsA…”
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Consequences of the Lack of TNFR1 in Ouabain Response in the Hippocampus of C57BL/6J Mice by Kinoshita, Paula Fernanda, Orellana, Ana Maria, Andreotti, Diana Zukas, de Souza, Giovanna Araujo, de Mello, Natalia Prudente, de Sá Lima, Larissa, Kawamoto, Elisa Mitiko, Scavone, Cristoforo

“…Ouabain is a cardiac glycoside that has a protective effect against neuroinflammation at low doses through Na /K -ATPase signaling and that can activate tumor…”
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