Search Results - "De Rosa, Enrica"

Tutorial: using nanoneedles for intracellular delivery by Chiappini, Ciro, Chen, Yaping, Aslanoglou, Stella, Mariano, Anna, Mollo, Valentina, Mu, Huanwen, De Rosa, Enrica, He, Gen, Tasciotti, Ennio, Xie, Xi, Santoro, Francesca, Zhao, Wenting, Voelcker, Nicolas H., Elnathan, Roey

“…Intracellular delivery of advanced therapeutics, including biologicals and supramolecular agents, is complex because of the natural biological barriers that…”
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Multi-composite bioactive osteogenic sponges featuring mesenchymal stem cells, platelet-rich plasma, nanoporous silicon enclosures, and Peptide amphiphiles for rapid bone regeneration by Murphy, Matthew B, Blashki, Daniel, Buchanan, Rachel M, Fan, Dongmei, De Rosa, Enrica, Shah, Ramille N, Stupp, Samuel I, Weiner, Bradley K, Simmons, Paul J, Ferrari, Mauro, Tasciotti, Ennio

“…A novel bioactive sponge was created with a composite of type I collagen sponges or porous poly(e-caprolactone) (PCL) scaffolds, platelet-rich plasma (PRP),…”
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Phosphoprotein-based biomarkers as predictors for cancer therapy by Carter, Angela M., Tan, Chunfeng, Pozo, Karine, Telange, Rahul, Molinaro, Roberto, Guo, Ailan, De Rosa, Enrica, Martinez, Jonathan O., Zhang, Shanrong, Kumar, Nilesh, Takahashi, Masaya, Wiederhold, Thorsten, Ghayee, Hans K., Oltmann, Sarah C., Pacak, Karel, Woltering, Eugene A., Hatanpaa, Kimmo J., Nwariaku, Fiemu E., Grubbs, Elizabeth G., Gill, Anthony J., Robinson, Bruce, Gillardon, Frank, Reddy, Sushanth, Jaskula-Sztul, Renata, Mobley, James A., Mukhtar, M. Shahid, Tasciotti, Ennio, Chen, Herbert, Bibb, James A.

“…Disparities in cancer patient responses have prompted widespread searches to identify differences in sensitive vs. nonsensitive populations and form the basis…”
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Engineered biomimetic nanovesicles show intrinsic anti-inflammatory properties for the treatment of inflammatory bowel diseases by Corbo, Claudia, Cromer, Walter E, Molinaro, Roberto, Toledano Furman, Naama E, Hartman, Kelly A, De Rosa, Enrica, Boada, Christian, Wang, Xin, Zawieja, David C, Agostini, Marco, Salvatore, Francesco, Abraham, Bincy P, Tasciotti, Ennio

“…Inflammatory bowel disease (IBD), which includes Crohn's disease and ulcerative colitis, is a chronic inflammatory condition of the gastrointestinal (GI)…”
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Assessment of spinal cord injury using ultrasound elastography in a rabbit model in vivo by Tang, Songyuan, Weiner, Bradley, Taraballi, Francesca, Haase, Candice, Stetco, Eliana, Mehta, Shail Maharshi, Shajudeen, Peer, Hogan, Matthew, De Rosa, Enrica, Horner, Philip J., Grande-Allen, K. Jane, Shi, Zhaoyue, Karmonik, Christof, Tasciotti, Ennio, Righetti, Raffaella

“…The effect of the mechanical micro-environment on spinal cord injury (SCI) and treatment effectiveness remains unclear. Currently, there are limited imaging…”
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Mesoporous Silicon-PLGA Composite Microspheres for the Double Controlled Release of Biomolecules for Orthopedic Tissue Engineering by Fan, Dongmei, De Rosa, Enrica, Murphy, Matthew B., Peng, Yang, Smid, Christine A., Chiappini, Ciro, Liu, Xuewu, Simmons, Paul, Weiner, Bradley K., Ferrari, Mauro, Tasciotti, Ennio

“…In this study, poly(dl‐lactide‐co‐glycolide)/porous silicon (PLGA/pSi) composite microspheres, synthesized by a solid‐in‐oil‐in‐water (S/O/W) emulsion method,…”
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Immunomodulatory biomimetic nanoparticles target articular cartilage trauma after systemic administration by Mancino, Chiara, Pasto, Anna, De Rosa, Enrica, Dolcetti, Luigi, Rasponi, Marco, McCulloch, Patrick, Taraballi, Francesca

“…Post-traumatic osteoarthritis (PTOA) is one of the leading causes of disability in developed countries and accounts for 12% of all osteoarthritis cases in the…”
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Liposome-Embedding Silicon Microparticle for Oxaliplatin Delivery in Tumor Chemotherapy by Cevenini, Armando, Celia, Christian, Orrù, Stefania, Sarnataro, Daniela, Raia, Maddalena, Mollo, Valentina, Locatelli, Marcello, Imperlini, Esther, Peluso, Nicoletta, Peltrini, Rosa, De Rosa, Enrica, Parodi, Alessandro, Del Vecchio, Luigi, Di Marzio, Luisa, Fresta, Massimo, Netti, Paolo Antonio, Shen, Haifa, Liu, Xuewu, Tasciotti, Ennio, Salvatore, Francesco

“…Mesoporous silicon microparticles (MSMPs) can incorporate drug-carrying nanoparticles (NPs) into their pores. An NP-loaded MSMP is a multistage vector (MSV)…”
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Tyrosine kinase inhibitor-loaded biomimetic nanoparticles as a treatment for osteosarcoma by Giordano, Federica, Lenna, Stefania, Baudo, Gherardo, Rampado, Riccardo, Massaro, Matteo, De Rosa, Enrica, Ewing, April, Kurenbekova, Lyazat, Agostini, Marco, Yustein, Jason T., Taraballi, Francesca

“…Small-molecule tyrosine kinase inhibitors (TKIs) represent a potentially powerful approach to the treatment of osteosarcoma (OS). However, dose-limiting…”
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LDL-Based Lipid Nanoparticle Derived for Blood Plasma Accumulates Preferentially in Atherosclerotic Plaque by Boada, Christian A, Zinger, Assaf, Rohen, Scott, Martinez, Jonathan O, Evangelopoulos, Michael, Molinaro, Roberto, Lu, Madeleine, Villarreal-Leal, Ramiro Alejandro, Giordano, Federica, Sushnitha, Manuela, De Rosa, Enrica, Simonsen, Jens B, Shevkoplyas, Sergey, Taraballi, Francesca, Tasciotti, Ennio

“…Apolipoprotein-based drug delivery is a promising approach to develop safe nanoparticles capable of targeted drug delivery for various diseases. In this work,…”
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Biomimetic Nanoparticles as a Theranostic Tool for Traumatic Brain Injury by Zinger, Assaf, Soriano, Sirena, Baudo, Gherardo, De Rosa, Enrica, Taraballi, Francesca, Villapol, Sonia

“…Traumatic brain injury (TBI) triggers both central and peripheral inflammatory responses. Existing pharmacological drugs are unable to effectively and quickly…”
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Enhancing Inflammation Targeting Using Tunable Leukocyte-Based Biomimetic Nanoparticles by Zinger, Assaf, Sushnitha, Manuela, Naoi, Tomoyuki, Baudo, Gherardo, De Rosa, Enrica, Chang, Jenny, Tasciotti, Ennio, Taraballi, Francesca

“…Biomimetic nanoparticles aim to effectively emulate the behavior of either cells or exosomes. Leukocyte-based biomimetic nanoparticles, for instance,…”
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Biodegradable Nanoneedles for Localized Delivery of Nanoparticles in Vivo: Exploring the Biointerface by Chiappini, Ciro, Martinez, Jonathan O, De Rosa, Enrica, Almeida, Carina S, Tasciotti, Ennio, Stevens, Molly M

“…Nanoneedles display potential in mediating the delivery of drugs and biologicals, as well as intracellular sensing and single-cell stimulation, through direct…”
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Soft Discoidal Polymeric Nanoconstructs Resist Macrophage Uptake and Enhance Vascular Targeting in Tumors by Key, Jaehong, Palange, Anna Lisa, Gentile, Francesco, Aryal, Santosh, Stigliano, Cinzia, Di Mascolo, Daniele, De Rosa, Enrica, Cho, Minjung, Lee, Yeonju, Singh, Jaykrishna, Decuzzi, Paolo

“…Most nanoparticles for biomedical applications originate from the self-assembling of individual constituents through molecular interactions and possess limited…”
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Unveiling the in Vivo Protein Corona of Circulating Leukocyte-like Carriers by Corbo, Claudia, Molinaro, Roberto, Taraballi, Francesca, Toledano Furman, Naama E, Hartman, Kelly A, Sherman, Michael B, De Rosa, Enrica, Kirui, Dickson K, Salvatore, Francesco, Tasciotti, Ennio

“…Understanding interactions occurring at the interface between nanoparticles and biological components is an urgent challenge in nanomedicine due to their…”
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TPA Immobilization on Iron Oxide Nanocubes and Localized Magnetic Hyperthermia Accelerate Blood Clot Lysis by Voros, Eszter, Cho, Minjung, Ramirez, Maricela, Palange, Anna Lisa, De Rosa, Enrica, Key, Jaehong, Garami, Zsolt, Lumsden, Alan B., Decuzzi, Paolo

“…The low specificity and high risk of intracranial hemorrhage associated with currently approved thrombolytic therapies limit their efficacy in recanalizing…”
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Leukocyte-mimicking nanovesicles for effective doxorubicin delivery to treat breast cancer and melanoma by Molinaro, Roberto, Martinez, Jonathan O, Zinger, Assaf, De Vita, Alessandro, Storci, Gianluca, Arrighetti, Noemi, De Rosa, Enrica, Hartman, Kelly A, Basu, Nupur, Taghipour, Nima, Corbo, Claudia, Tasciotti, Ennio

“…In the last decades, several approaches were developed to design drug delivery systems to address the multiple biological barriers encountered after…”
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Abstract 311: Ponatinib loaded leukocyte-based nanoparticles for osteosarcoma treatment in sarcosphere tumor model by Giordano, Federica, Lenna, Stefania, Rampado, Riccardo, Ewing, April, Baudo, Gherardo, Massaro, Matteo, Zinger, Assaf, De Rosa, Enrica, Yustein, Jason T, Taraballi, Francesca

“…Abstract Osteosarcoma (OS) is the most common pediatric bone tumor with a worldwide incidence of 3.4 cases per million people annually. Unfortunately, current…”
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Biomimetic nanoparticles with enhanced affinity towards activated endothelium as versatile tools for theranostic drug delivery by Martinez, Jonathan O, Molinaro, Roberto, Hartman, Kelly A, Boada, Christian, Sukhovershin, Roman, De Rosa, Enrica, Kirui, Dickson, Zhang, Shanrong, Evangelopoulos, Michael, Carter, Angela M, Bibb, James A, Cooke, John P, Tasciotti, Ennio

“…Activation of the vascular endothelium is characterized by increased expression of vascular adhesion molecules and chemokines. This activation occurs early in…”
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Enhancing Vascularization through the Controlled Release of Platelet-Derived Growth Factor-BB by Minardi, Silvia, Pandolfi, Laura, Taraballi, Francesca, Wang, Xin, De Rosa, Enrica, Mills, Zachary D, Liu, Xuewu, Ferrari, Mauro, Tasciotti, Ennio

“…Using delivery systems to control the in vivo release of growth factors (GFs) for tissue engineering applications is extremely desirable as the clinical use of…”
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