Search Results - "De Robertis, Eddy M."

Cerberus is a head-inducing secreted factor expressed in the anterior endoderm of Spemann's organizer by Bouwmeester, Tewis, Kim, Sung-Hyun, Sasai, Yoshiki, Lu, Bin, Robertis, Eddy M. De

“…An abundant cDNA enriched in Spemann's organizer, cerberus, was isolated by differential screening. It encodes a secreted protein that is expressed in the…”
Get full text

Integration of IGF, FGF, and anti-BMP signals via Smad1 phosphorylation in neural induction by Pera, Edgar M, Ikeda, Atsushi, Eivers, Edward, De Robertis, Eddy M

“…How do very diverse signaling pathways induce neural differentiation in Xenopus? Anti-BMP (Chordin), FGF8, and IGF2 signals are integrated in the embryo via…”
Get full text

Paraxial protocadherin coordinates cell polarity during convergent extension via Rho A and JNK by Unterseher, Frank, Hefele, Joerg A, Giehl, Klaudia, De Robertis, Eddy M, Wedlich, Doris, Schambony, Alexandra

“…Convergent extension movements occur ubiquitously in animal development. This special type of cell movement is controlled by the Wnt/planar cell polarity (PCP)…”
Get full text

Frzb-1 Is a Secreted Antagonist of Wnt Signaling Expressed in the Spemann Organizer by Leyns, Luc, Bouwmeester, Tewis, Kim, Sung-Hyun, Piccolo, Stefano, De Robertis, Eddy M

“…Frzb-1 is a secreted protein containing a domain similar to the putative Wnt-binding region of the frizzled family of transmembrane receptors. Frzb-1 is widely…”
Get full text

Cleavage of Chordin by Xolloid metalloprotease suggests a role for proteolytic processing in the regulation of Spemann organizer activity by Piccolo, S, Agius, E, Lu, B, Goodman, S, Dale, L, De Robertis, E M

“…The Xolloid secreted metalloprotease, a tolloid-related protein, was found to cleave Chordin and Chordin/BMP-4 complexes at two specific sites in biochemical…”
Get full text

Sirenomelia in Bmp7 and Tsg compound mutant mice: requirement for Bmp signaling in the development of ventral posterior mesoderm by Zakin, Lise, Reversade, Bruno, Kuroda, Hiroki, Lyons, Karen M, De Robertis, Eddy M

“…Sirenomelia or mermaid-like phenotype is one of the principal human congenital malformations that can be traced back to the stage of gastrulation. Sirenomelia…”
Get full text

Regulation of neural induction by the Chd and Bmp-4 antagonistic patterning signals in Xenopus by Sasai, Yoshiki, Lu, Bin, Steinbeisser, Herbert, De Robertis, Eddy M

“…In Drosophila the amount of neurogenic ectoderm, from which the central nervous system (CNS) derives, is regulated by a dorsal-ventral system of positional…”
Get full text

The Xenopus Dorsalizing Factor noggin Ventralizes Drosophila Embryos by Preventing DPP from Activating Its Receptor by Holley, Scott A, Neul, Jeffrey L, Attisano, Liliana, Wrana, Jeffrey L, Sasai, Yoshiki, O'Connor, Michael B, De Robertis, Eddy M, Ferguson, Edwin L

“…noggin is expressed in the Spemann organizer region of the Xenopus embryo and can promote dorsal cell fates within the mesoderm and neural development within…”
Get full text

Targeted mutation of the murine goosecoid gene results in craniofacial defects and neonatal death by Yamada, G, Mansouri, A, Torres, M, Stuart, E T, Blum, M, Schultz, M, De Robertis, E M, Gruss, P

“…The goosecoid gene encodes a homeodomain-containing protein that has been identified in a number of species and has been implicated in a variety of key…”
Get full text

Transplacental delivery of the Wnt antagonist Frzb1 inhibits development of caudal paraxial mesoderm and skeletal myogenesis in mouse embryos by Borello, U, Coletta, M, Tajbakhsh, S, Leyns, L, De Robertis, E M, Buckingham, M, Cossu, G

“…Axial structures (neural tube/notochord) and surface ectoderm activate myogenesis in the mouse embryo; their action can be reproduced, at least in part, by…”
Get full text

Herbert Steinbeisser: a life with the Xenopus embryo by De Robertis, Eddy M, Niehrs, Christof

Get full text

A conserved system for dorsal-ventral patterning in insects and vertebrates involving sog and chordin by Holley, Scott A, Jackson, P. David, Sasai, Yoshiki, Lu, Bin, Robertis, Eddy M. De, Hoffmann, F. Michael, Ferguson, Edwin L

Get full text

Neural induction and regionalisation in the chick embryo by STOREY, K. G, CROSSLEY, J. M, DE ROBERTIS, E. M, NORRIS, W. E, STERN, C. D

“…Induction and regionalisation of the chick nervous system were investigated by transplanting Hensen's node into the extra-embryonic region (area opaca margin)…”
Get full text

New twists on embryonic patterning. EMBO workshop: embryonic organizer signaling: the next frontiers by De Robertis, E M, Bouwmeester, T

Get full text

Ectodermal Patterning in Vertebrate Embryos by Sasai, Yoshiki, De Robertis, Eddy M.

“…Recent molecular insights on how the ectodermal layer is patterned in vertebrates are reviewed. Studies on the induction of the central nervous system (CNS) by…”
Get full text

The evolutionarily conserved BMP-binding protein Twisted gastrulation promotes BMP signalling by De Robertis, Eddy M, Oelgeschläger, Michael, Larraín, Juan, Geissert, Douglas

“…Dorsal-ventral patterning in vertebrate and Drosophila embryos requires a conserved system of extracellular proteins to generate a positional information…”
Get full text

Eddy M. De Robertis by De Robertis, Eddy M.

Get full text

GOOSECOID inhibits erythrocyte differentiation by competing with Rb for PU.1 binding in murine cells by KONISHI, Y, TOMINAGA, M, WATANABE, Y, IMAMURA, F, GOLDFARB, A, MAKI, R, BLUM, M, DE ROBERTIS, E. M, TOMINAGA, A

“…Misexpression of the dorsal mesodermal patterning factor goosecoid on the ventral side of amphibian embryos results in inhibition of blood formation in early…”
Get full text

Dorsoventral Patterning in Xenopus: Inhibition of Ventral Signals by Direct Binding of Chordin to BMP-4 by Piccolo, Stefano, Sasai, Yoshiki, Lu, Bin, De Robertis, Eddy M

“…Chordin (Chd) is an abundant protein secreted by Spemann organizer tissue during gastrulation. Chd antagonizes signaling by mature bone morphogenetic proteins…”
Get full text

Gradients of homeoproteins in developing feather buds by CHENG-MING CHUONG, OLIVER, G, TING, S. A, JEGALIAN, B. G, HAI MING CHEN, DE ROBERTIS, E. M

“…Homeoproteins are functionally involved in pattern formation. Recently, homeoproteins have been shown to be distributed in a graded fashion in developing limb…”
Get full text