Search Results - "De Raeymaecker, Joren"

Structures of the heart specific SERCA2a Ca2+‐ATPase by Sitsel, Aljona, De Raeymaecker, Joren, Drachmann, Nikolaj Düring, Derua, Rita, Smaardijk, Susanne, Andersen, Jacob Lauwring, Vandecaetsbeek, Ilse, Chen, Jialin, De Maeyer, Marc, Waelkens, Etienne, Olesen, Claus, Vangheluwe, Peter, Nissen, Poul

“…The sarcoplasmic/endoplasmic reticulum Ca 2+ ‐ATPase 2a (SERCA2a) performs active reuptake of cytoplasmic Ca 2+ and is a major regulator of cardiac muscle…”
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Pharmacophore modeling: advances, limitations, and current utility in drug discovery by Qing, Xiaoyu, Lee, Xiao Yin, De Raeymaeker, Joren, Tame, Jeremy R.H, Zhang, Kam Y.J, De Maeyer, Marc, Voet, Arnout R.D

“…Pharmacophore modeling is a successful yet very diverse subfield of computer-aided drug design. The concept of the pharmacophore has been widely applied to the…”
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Structure/activity relationship of thapsigargin inhibition on the purified Golgi/secretory pathway Ca2+/Mn2+-transport ATPase (SPCA1a) by Chen, Jialin, De Raeymaecker, Joren, Hovgaard, Jannik Brøndsted, Smaardijk, Susanne, Vandecaetsbeek, Ilse, Wuytack, Frank, Møller, Jesper Vuust, Eggermont, Jan, De Maeyer, Marc, Christensen, Søren Brøgger, Vangheluwe, Peter

“…The Golgi/secretory pathway Ca2+/Mn2+-transport ATPase (SPCA1a) is implicated in breast cancer and Hailey-Hailey disease. Here, we purified recombinant human…”
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Structures of the heart specific SERCA 2a Ca 2+ ‐ ATP ase by Sitsel, Aljona, De Raeymaecker, Joren, Drachmann, Nikolaj Düring, Derua, Rita, Smaardijk, Susanne, Andersen, Jacob Lauwring, Vandecaetsbeek, Ilse, Chen, Jialin, De Maeyer, Marc, Waelkens, Etienne, Olesen, Claus, Vangheluwe, Peter, Nissen, Poul

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In silico, in vitro and cellular analysis with a kinome-wide inhibitor panel correlates cellular LRRK2 dephosphorylation to inhibitor activity on LRRK2 by Vancraenenbroeck, Renée, De Raeymaecker, Joren, Lobbestael, Evy, Gao, Fangye, De Maeyer, Marc, Voet, Arnout, Baekelandt, Veerle, Taymans, Jean-Marc

“…Leucine-rich repeat kinase 2 (LRRK2) is a complex, multidomain protein which is considered a valuable target for potential disease-modifying therapeutic…”
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Structures of the heart specific SERCA2a Ca 2+ -ATPase by Sitsel, Aljona, De Raeymaecker, Joren, Drachmann, Nikolaj Düring, Derua, Rita, Smaardijk, Susanne, Andersen, Jacob Lauwring, Vandecaetsbeek, Ilse, Chen, Jialin, De Maeyer, Marc, Waelkens, Etienne, Olesen, Claus, Vangheluwe, Peter, Nissen, Poul

“…The sarcoplasmic/endoplasmic reticulum Ca -ATPase 2a (SERCA2a) performs active reuptake of cytoplasmic Ca and is a major regulator of cardiac muscle…”
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Structure/activity relationship of thapsigargin inhibition on the purified Golgi/secretory pathway Ca 2+ /Mn 2+ -transport ATPase (SPCA1a) by Chen, Jialin, De Raeymaecker, Joren, Hovgaard, Jannik Brøndsted, Smaardijk, Susanne, Vandecaetsbeek, Ilse, Wuytack, Frank, Møller, Jesper Vuust, Eggermont, Jan, De Maeyer, Marc, Christensen, Søren Brøgger, Vangheluwe, Peter

“…The Golgi/secretory pathway Ca /Mn -transport ATPase (SPCA1a) is implicated in breast cancer and Hailey-Hailey disease. Here, we purified recombinant human…”
Get full text