Search Results - "De Ponti, Anna"

Identification of 4,5-Dihydro-1H-pyrazolo[4,3-h]quinazoline Derivatives as a New Class of Orally and Selective Polo-Like Kinase 1 Inhibitors by Beria, Italo, Ballinari, Dario, Bertrand, Jay Aaron, Borghi, Daniela, Bossi, Roberto Tiberio, Brasca, Maria Gabriella, Cappella, Paolo, Caruso, Michele, Ceccarelli, Walter, Ciavolella, Antonella, Cristiani, Cinzia, Croci, Valter, De Ponti, Anna, Fachin, Gabriele, Ferguson, Ronald Dale, Lansen, Jacqueline, Moll, Jurgen Karl, Pesenti, Enrico, Posteri, Helena, Perego, Rita, Rocchetti, Maurizio, Storici, Paola, Volpi, Daniele, Valsasina, Barbara

“…Polo-like kinase 1 (Plk1) is a fundamental regulator of mitotic progression whose overexpression is often associated with oncogenesis and therefore is…”
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NMS-P937, an orally available, specific small-molecule polo-like kinase 1 inhibitor with antitumor activity in solid and hematologic malignancies by Valsasina, Barbara, Beria, Italo, Alli, Cristina, Alzani, Rachele, Avanzi, Nilla, Ballinari, Dario, Cappella, Paolo, Caruso, Michele, Casolaro, Alessia, Ciavolella, Antonella, Cucchi, Ulisse, De Ponti, Anna, Felder, Eduard, Fiorentini, Francesco, Galvani, Arturo, Gianellini, Laura M, Giorgini, Maria L, Isacchi, Antonella, Lansen, Jaqueline, Pesenti, Enrico, Rizzi, Simona, Rocchetti, Maurizio, Sola, Francesco, Moll, Jürgen

“…Polo-like kinase 1 (PLK1) is a serine/threonine protein kinase considered to be the master player of cell-cycle regulation during mitosis. It is indeed…”
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Identification of 4,5-Dihydro-1 H -pyrazolo[4,3- h ]quinazoline Derivatives as a New Class of Orally and Selective Polo-Like Kinase 1 Inhibitors by Beria, Italo, Ballinari, Dario, Bertrand, Jay Aaron, Borghi, Daniela, Bossi, Roberto Tiberio, Brasca, Maria Gabriella, Cappella, Paolo, Caruso, Michele, Ceccarelli, Walter, Ciavolella, Antonella, Cristiani, Cinzia, Croci, Valter, De Ponti, Anna, Fachin, Gabriele, Ferguson, Ronald Dale, Lansen, Jacqueline, Moll, Jurgen Karl, Pesenti, Enrico, Posteri, Helena, Perego, Rita, Rocchetti, Maurizio, Storici, Paola, Volpi, Daniele, Valsasina, Barbara

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Discovery of NMS-E973 as novel, selective and potent inhibitor of heat shock protein 90 (Hsp90) by Brasca, Maria Gabriella, Mantegani, Sergio, Amboldi, Nadia, Bindi, Simona, Caronni, Dannica, Casale, Elena, Ceccarelli, Walter, Colombo, Nicoletta, De Ponti, Anna, Donati, Daniele, Ermoli, Antonella, Fachin, Gabriele, Felder, Eduard R., Ferguson, Ronald D., Fiorelli, Claudio, Guanci, Marco, Isacchi, Antonella, Pesenti, Enrico, Polucci, Paolo, Riceputi, Laura, Sola, Francesco, Visco, Carlo, Zuccotto, Fabio, Fogliatto, Gianpaolo

“…Fragment based approach and subsequent optimization of the fragment 1 led to the identification of the heat shock protein 90 (Hsp90) inhibitor 18 (NMS-E973),…”
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NMS-E973, a Novel Synthetic Inhibitor of Hsp90 with Activity against Multiple Models of Drug Resistance to Targeted Agents, Including Intracranial Metastases by FOGLIATTO, Gianpaolo, GIANELLINI, Laura, PAOLUCCI, Mauro, POLUCCI, Paolo, RUSSO, Micaela, SOLA, Francesco, VALSASINA, Barbara, VISCO, Carlo, ZUCCOTTO, Fabio, DONATI, Daniele, FELDER, Eduard, PESENTI, Enrico, BRASCA, Maria G, GALVANI, Arturo, MANTEGANI, Sergio, ISACCHI, Antonella, CASALE, Elena, BALLINARI, Dario, CIOMEI, Marina, DEGRASSI, Anna, DE PONTI, Anna, GERMANI, Massimiliano, GUANCI, Marco

“…Recent developments of second generation Hsp90 inhibitors suggested a potential for development of this class of molecules also in tumors that have become…”
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Phosphorylation of TCTP as a Marker for Polo-like Kinase-1 Activity In Vivo by CUCCHI, Ulisse, GIANELLINI, Laura M, GIORGINI, Maria L, CAPPELLA, Paolo, BERIA, Italo, VALSASINA, Barbara, DE PONTI, Anna, SOLA, Francesco, ALZANI, Rachele, PATTON, Veronica, PEZZONI, Alice, TROIANI, Sonia, SACCARDO, Maria B, RIZZI, Simona

“…Polo-like kinase 1 (PLK1) is the master regulator of mitosis and a target for anticancer therapy. To develop a marker of PLK1 activity in cells and tumour…”
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Corrigendum to “Discovery of NMS-E973 as novel, selective and potent inhibitor of heat shock protein 90 (Hsp90)” [Bioorg. Med. Chem. 21 (2013) 7047–7063] by Brasca, Maria Gabriella, Mantegani, Sergio, Amboldi, Nadia, Bindi, Simona, Caronni, Dannica, Casale, Elena, Ceccarelli, Walter, Colombo, Nicoletta, De Ponti, Anna, Donati, Daniele, Ermoli, Antonella, Fachin, Gabriele, Felder, Eduard R., Ferguson, Ronald D., Fiorelli, Claudio, Guanci, Marco, Isacchi, Antonella, Pesenti, Enrico, Polucci, Paolo, Riceputi, Laura, Sola, Francesco, Visco, Carlo, Zuccotto, Fabio, Fogliatto, Gianpaolo

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Abstract A213: Potent anticancer activity in vitro and in vivo by NMS-E973, a novel synthetic inhibitor of HSP90 by Fogliatto, Gianpaolo, Mantegani, Sergio, Amboldi, Nadia, Ballinari, Dario, Brasca, Maria Gabriella, Caprera, Francesco, Cappella, Paolo, Casale, Elena, De Ponti, Anna, Guanci, Marco, Paolucci, Mauro, Sola, Francesco, Valsasina, Barbara, Visco, Carlo, Zuccotto, Fabio, Colotta, Francesco, Felder, Eduard, Donati, Daniele, Moll, Juergen, Galvani, Arturo, Pesenti, Enrico, Isacchi, Antonella

“…Abstract The molecular chaperone heat shock protein 90 (HSP90) is essential for the conformational maturation and stability of a variety of proteins, including…”
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How to increase patient knowledge of their coronary heart disease: impact of an educational meeting led by nurses by Amodeo, Raffaella, De Ponti, Anna, Sorbara, Loredana, Avanzini, Fausto, Di Giulio, Paola, De Martini, Mario

“…Most patients discharged after an acute coronary event or a coronary revascularization do not have adequate knowledge of the nature of their disease and of the…”
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Effectiveness of a nurse-led educational intervention for patients admitted for acute coronary syndrome by Avanzini, Fausto, Di Giulio, Paola, Amodeo, Raffaella, Baldo, Sabina, Bergna, Maria Luisa, Busi, Giovanna, Carlino, Liliana, Colombo, Fabio, Cotza, Roberta, De Ponti, Anna, Di Rocco, Egidia, Marigliani, Catia, Negri, Eva, Roncaglioni, Maria Carla, Saltarel, Ivan, Sorbara, Loredana, Tavani, Alessandra, De Martini, Mario

“…To assess the effectiveness of a nurse-led class with phone follow-up, to help patients achieve lifestyle changes after an acute coronary syndrome (ACS). Each…”
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Knowledge and lifestyles of patients: a survey on patients admitted with acute coronary syndrome in the CCU of an Italian hospital by De Ponti, Anna, Sorbara, Loredana, Amodeo, Raffaella, Imperatore, Patrizia Fusar, Berizzi, Margherita, Di Rocco, Egidia, Saltarel, Ivan, Marigliani, Catia, Avanzini, Fausto

“…The lifestyles before hospital admission, knowledge on their illness and lifestyles after the acute coronary event were analysed with questionnaires, in three…”
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An health education program for patients admitted to CCU for an acute coronary event by Amodeo, Raffaello, De Ponti, Anna, Sorbara, Loredana, Imperatore, Patrizia Fusar, Berizzi, Margherita, Di Rocco, Egidia, Saltarel, Ivan, Marigliani, Catia, Avanzini, Fausto

“…In spite of the broad recognition of the importance of health education, time for structured one-to -one initiatives of health education during the hospital…”
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