Search Results - "De Pinto, Vito"

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  1. 1

    Is the secret of VDAC Isoforms in their gene regulation? Characterization of human VDAC genes expression profile, promoter activity, and transcriptional regulators by Zinghirino, Federica, Pappalardo, Xena Giada, Messina, Angela, Guarino, Francesca, De Pinto, Vito

    “…VDACs (voltage-dependent anion-selective channels) are pore-forming proteins of the outer mitochondrial membrane, whose permeability is primarily due to VDACs'…”
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    Outer membrane VDAC1 controls permeability transition of the inner mitochondrial membrane in cellulo during stress-induced apoptosis by Tomasello, Flora, Messina, Angela, Lartigue, Lydia, Schembri, Laura, Medina, Chantal, Reina, Simona, Thoraval, Didier, Crouzet, Marc, Ichas, François, De Pinto, Vito, De Giorgi, Francesca

    Published in Cell research (01-12-2009)
    “…Voltage-dependent anion channel (VDAC)I is the main channel of the mitochondrial outer membrane (MOM) and it has been proposed to be part of the permeability…”
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  3. 3

    Renaissance of VDAC: New Insights on a Protein Family at the Interface between Mitochondria and Cytosol by De Pinto, Vito

    Published in Biomolecules (Basel, Switzerland) (15-01-2021)
    “…It has become impossible to review all the existing literature on Voltage-Dependent Anion selective Channel (VDAC) in a single article. A real Renaissance of…”
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    Role of cysteines in mammalian VDAC isoforms' function by De Pinto, Vito, Reina, Simona, Gupta, Ankit, Messina, Angela, Mahalakshmi, Radhakrishnan

    Published in Biochimica et biophysica acta (01-08-2016)
    “…In this mini-review, we analyze the influence of cysteines in the structure and activity of mitochondrial outer membrane mammalian VDAC isoforms. The three…”
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  5. 5

    VDAC1 as Pharmacological Target in Cancer and Neurodegeneration: Focus on Its Role in Apoptosis by Magrì, Andrea, Reina, Simona, De Pinto, Vito

    Published in Frontiers in chemistry (06-04-2018)
    “…Cancer and neurodegeneration are different classes of diseases that share the involvement of mitochondria in their pathogenesis. Whereas the high glycolytic…”
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  6. 6

    VDAC as a Cellular Hub: Docking Molecules and Interactions by Kmita, Hanna, Messina, Angela Anna, De Pinto, Vito

    “…The voltage-dependent anion channel (VDAC) is the primary regulating pathway of water-soluble metabolites and ions across the mitochondrial outer membrane…”
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  7. 7

    Molecular and functional characterization of VDAC2 purified from mammal spermatozoa by Menzel, Viviana A, Cassará, M Carolina, Benz, Roland, de Pinto, Vito, Messina, Angela, Cunsolo, Vincenzo, Saletti, Rosaria, Hinsch, Klaus-Dieter, Hinsch, Elvira

    Published in Bioscience reports (22-07-2009)
    “…VDAC (voltage-dependent anion channel) is the pore-forming protein located in the outer mitochondrial membrane. In higher eukaryotes, three genes encode VDAC…”
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  8. 8

    Novel Compounds Targeting the Mitochondrial Protein VDAC1 Inhibit Apoptosis and Protect against Mitochondrial Dysfunction by Ben-Hail, Danya, Begas-Shvartz, Racheli, Shalev, Moran, Shteinfer-Kuzmine, Anna, Gruzman, Arie, Reina, Simona, De Pinto, Vito, Shoshan-Barmatz, Varda

    Published in The Journal of biological chemistry (25-11-2016)
    “…Apoptosis is thought to play a critical role in several pathological processes, such as neurodegenerative diseases (i.e. Parkinson's and Alzheimer's diseases)…”
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  9. 9

    VDAC Genes Expression and Regulation in Mammals by Zinghirino, Federica, Pappalardo, Xena Giada, Messina, Angela, Nicosia, Giuseppe, De Pinto, Vito, Guarino, Francesca

    Published in Frontiers in physiology (05-08-2021)
    “…VDACs are pore-forming proteins, coating the mitochondrial outer membrane, and playing the role of main regulators for metabolites exchange between cytosol and…”
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  10. 10

    Voltage-dependent anion-selective channel (VDAC) in the plasma membrane by De Pinto, Vito, Messina, Angela, Lane, Darius J.R., Lawen, Alfons

    Published in FEBS letters (03-05-2010)
    “…Voltage-dependent anion channels (VDACs) have originally been characterized as mitochondrial porins. Starting in the late 1980s, however, evidence began to…”
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    Voltage Dependent Anion Channel 3 (VDAC3) protects mitochondria from oxidative stress by Reina, Simona, Nibali, Stefano Conti, Tomasello, Marianna Flora, Magrì, Andrea, Messina, Angela, De Pinto, Vito

    Published in Redox biology (01-05-2022)
    “…Unraveling the role of VDAC3 within living cells is challenging and still requires a definitive answer. Unlike VDAC1 and VDAC2, the outer mitochondrial…”
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  13. 13

    VDAC3 As a Potential Marker of Mitochondrial Status Is Involved in Cancer and Pathology by Reina, Simona, Guarino, Francesca, Magrì, Andrea, De Pinto, Vito

    Published in Frontiers in oncology (23-12-2016)
    “…VDAC3 is the least known isoform of the mammalian voltage-dependent anion selective channels of the outer mitochondrial membrane. It has been recently shown…”
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    Charged residues distribution modulates selectivity of the open state of human isoforms of the voltage dependent anion-selective channel by Amodeo, Giuseppe Federico, Scorciapino, Mariano Andrea, Messina, Angela, De Pinto, Vito, Ceccarelli, Matteo

    Published in PloS one (01-08-2014)
    “…Voltage Dependent Anion-selective Channels (VDACs) are pore-forming proteins located in the outer mitochondrial membrane. They are responsible for the access…”
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  16. 16

    Characterization of human VDAC isoforms: A peculiar function for VDAC3? by De Pinto, Vito, Guarino, Francesca, Guarnera, Andrea, Messina, Angela, Reina, Simona, Tomasello, Flora M., Palermo, Vanessa, Mazzoni, Cristina

    Published in Biochimica et biophysica acta (01-06-2010)
    “…VDACs are a family of pore-forming proteins mainly located in the mitochondrial outer membrane. In mammals three isoforms exist. In this work we review the…”
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  17. 17

    The voltage-dependent anion selective channel 1 (VDAC1) topography in the mitochondrial outer membrane as detected in intact cell by Tomasello, Marianna F, Guarino, Francesca, Reina, Simona, Messina, Angela, De Pinto, Vito

    Published in PloS one (06-12-2013)
    “…Voltage-Dependent Anion selective Channel maintains the permeability of the outer mitochondrial membrane and is relevant in bioenergetic metabolism and…”
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  18. 18

    Post-translational modifications of VDAC1 and VDAC2 cysteines from rat liver mitochondria by Saletti, Rosaria, Reina, Simona, Pittalà, Maria G.G., Magrì, Andrea, Cunsolo, Vincenzo, Foti, Salvatore, De Pinto, Vito

    “…VDACs three isoforms (VDAC1, VDAC2, VDAC3) are integral proteins of the outer mitochondrial membrane whose primary function is to permit the communication and…”
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    A High Resolution Mass Spectrometry Study Reveals the Potential of Disulfide Formation in Human Mitochondrial Voltage-Dependent Anion Selective Channel Isoforms (hVDACs) by Pittalà, Maria G G, Saletti, Rosaria, Reina, Simona, Cunsolo, Vincenzo, De Pinto, Vito, Foti, Salvatore

    “…The voltage-dependent anion-selective channels (VDACs), which are also known as eukaryotic porins, are pore-forming proteins, which allow for the passage of…”
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