Search Results - "De Petris, Luigi"
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Predicting Radiation Pneumonitis After Chemoradiation Therapy for Lung Cancer: An International Individual Patient Data Meta-analysis
Published in International journal of radiation oncology, biology, physics (01-02-2013)“…Background Radiation pneumonitis is a dose-limiting toxicity for patients undergoing concurrent chemoradiation therapy (CCRT) for non-small cell lung cancer…”
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Pooled Systemic Efficacy and Safety Data from the Pivotal Phase II Studies (NP28673 and NP28761) of Alectinib in ALK-positive Non-Small Cell Lung Cancer
Published in Journal of thoracic oncology (01-10-2017)“…Alectinib demonstrated clinical efficacy and an acceptable safety profile in two phase II studies (NP28761 and NP28673). Here we report the pooled efficacy and…”
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Differential prognostic impact of platelet-derived growth factor receptor expression in NSCLC
Published in Scientific reports (15-07-2019)“…Preclinical evidence suggests that stromal expression of platelet-derived growth factor receptors (PDGFRs) stimulates tumor development and diminishes…”
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Exploring the discrepancies between clinical trials and real‐world data: A small‐cell lung cancer study
Published in Clinical and translational science (01-08-2024)“…The potential of real‐world data to inform clinical trial design and supplement control arms has gained much interest in recent years. The most common approach…”
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Cancer Cachexia and Antitumor Immunity: Common Mediators and Potential Targets for New Therapies
Published in Life (Basel, Switzerland) (12-06-2022)“…Cancer cachexia syndrome (CCS) is a multifactorial metabolic syndrome affecting a significant proportion of patients. CCS is characterized by progressive…”
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Caring for patients with cancer in the COVID-19 era
Published in Nature medicine (01-05-2020)“…The current COVID-19 pandemic challenges oncologists to profoundly re-organize oncological care in order to dramatically reduce hospital visits and admissions…”
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Alectinib in Crizotinib-Refractory ALK-Rearranged Non-Small-Cell Lung Cancer: A Phase II Global Study
Published in Journal of clinical oncology (01-03-2016)“…Crizotinib confers improved progression-free survival compared with chemotherapy in anaplastic lymphoma kinase (ALK)-rearranged non-small-cell lung cancer…”
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The prognostic implications of Notch1, Hes1, Ascl1, and DLL3 protein expression in SCLC patients receiving platinum-based chemotherapy
Published in PloS one (26-10-2020)“…The aim was to analyse the tumor expression of Notch1, Hes1, Ascl1, and DLL3 in Small-Cell Lung Cancer (SCLC) and each such biomarker's potential association…”
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Exosomal RNA-profiling of pleural effusions identifies adenocarcinoma patients through elevated miR-200 and LCN2 expression
Published in Lung cancer (Amsterdam, Netherlands) (01-10-2018)“…•Pleural effusions provide an abundant source for liquid biopsy RNA-profiling.•Exosomal derived microRNAs provide superior diagnostic value compared to…”
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PD-1 expression in tumor infiltrating lymphocytes as a prognostic marker in early-stage non-small cell lung cancer
Published in Frontiers in oncology (26-09-2024)“…Programmed death ligand - 1 (PD-L1) expression is a well-established predictive biomarker for immunotherapy in non-small cell lung cancer (NSCLC). Programmed…”
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Outcome of Patients with NSCLC and Brain Metastases Treated with Immune Checkpoint Inhibitors in a 'Real-Life' Setting
Published in Cancers (10-12-2020)“…There is lack of data addressing the intracranial (IC) efficacy of immune checkpoint inhibitors (ICIs) on brain metastases (BM) in non-small cell lung cancer…”
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A novel analytical framework for risk stratification of real‐world data using machine learning: A small cell lung cancer study
Published in Clinical and translational science (01-10-2022)“…In recent studies, small cell lung cancer (SCLC) treatment guidelines based on Veterans’ Administration Lung Study Group limited/extensive disease staging and…”
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The role of p53 in treatment responses of lung cancer
Published in Biochemical and biophysical research communications (10-06-2005)“…Resistance to radio- and chemotherapy is a major problem in treatment responses of lung cancer. In this disease, biological markers, that can be predictive of…”
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Multiplex immune protein profiling of fine‐needle aspirates from patients with non‐small‐cell lung cancer reveals signatures associated with PD‐L1 expression and tumor stage
Published in Molecular oncology (01-11-2021)“…Biomarker signatures identified through minimally invasive procedures already at diagnosis of non‐small‐cell lung cancer (NSCLC) could help to guide treatment…”
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A combined gene expression tool for parallel histological prediction and gene fusion detection in non-small cell lung cancer
Published in Scientific reports (26-03-2019)“…Accurate histological classification and identification of fusion genes represent two cornerstones of clinical diagnostics in non-small cell lung cancer…”
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Genes and variants in hematopoiesis-related pathways are associated with gemcitabine/carboplatin-induced thrombocytopenia
Published in The pharmacogenomics journal (01-04-2020)“…Chemotherapy-induced myelosuppression, including thrombocytopenia, is a recurrent problem during cancer treatments that may require dose alterations or…”
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Factors Associated With Early Mortality in Patients Treated With Concurrent Chemoradiation Therapy for Locally Advanced Non-Small Cell Lung Cancer
Published in International journal of radiation oncology, biology, physics (01-03-2016)“…Purpose Concurrent chemoradiation therapy (con-CRT) is recommended for fit patients with locally advanced non-small cell lung cancer (LA-NSCLC) but is…”
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Author Correction: Caring for patients with cancer in the COVID-19 era
Published in Nature medicine (01-07-2020)“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Detection of Tumor-Associated Membrane Receptors on Extracellular Vesicles from Non-Small Cell Lung Cancer Patients via Immuno-PCR
Published in Cancers (22-02-2021)“…Precision cancer medicine for non-small-cell lung cancer (NSCLC) has increased patient survival. Nevertheless, targeted agents towards tumor-associated…”
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Ephrin B3 interacts with multiple EphA receptors and drives migration and invasion in non-small cell lung cancer
Published in Oncotarget (13-09-2016)“…Ephrin receptors (Ephs) are reported to control metastatic signaling of non-small cell lung cancer (NSCLC) and other tumors. Here we show for the first time…”
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