Search Results - "De Pauw, Aurelia"
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Mitochondrial (Dys)function in Adipocyte (De)differentiation and Systemic Metabolic Alterations
Published in The American journal of pathology (01-09-2009)“…In mammals, adipose tissue, composed of BAT and WAT, collaborates in energy partitioning and performs metabolic regulatory functions. It is the most flexible…”
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Crosstalk between mitochondrial (dys)function and mitochondrial abundance
Published in Journal of cellular physiology (01-06-2012)“…A controlled regulation of mitochondrial mass through either the production (biogenesis) or the degradation (mitochondrial quality control) of the organelle…”
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CREB activation induced by mitochondrial dysfunction triggers triglyceride accumulation in 3T3-L1 preadipocytes
Published in Journal of cell science (01-04-2006)“…Several mitochondrial pathologies are characterized by lipid redistribution and microvesicular cell phenotypes resulting from triglyceride accumulation in…”
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4
Mild mitochondrial uncoupling induces 3T3-L1 adipocyte de-differentiation by a PPARγ-independent mechanism, whereas TNFα-induced de-differentiation is PPARγ dependent
Published in Journal of cell science (2009)“…Impairment of mitochondrial activity affects lipid-metabolizing tissues and mild mitochondrial uncoupling has been proposed as a possible strategy to fight…”
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5
Mitochondrial biogenesis in mtDNA‐depleted cells involves a Ca2+‐dependent pathway and a reduced mitochondrial protein import
Published in The FEBS journal (01-10-2005)“…Alterations in mitochondrial activity resulting from defects in mitochondrial DNA (mtDNA) can modulate the biogenesis of mitochondria by mechanisms that are…”
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6
Mitochondrial dysfunction induces triglyceride accumulation in 3T3-L1 cells: role of fatty acid beta-oxidation and glucose
Published in Journal of lipid research (01-06-2005)“…Mitochondrial cytopathy has been associated with modifications of lipid metabolism in various situations, such as the acquisition of an abnormal adipocyte…”
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7
Mild mitochondrial uncoupling does not affect mitochondrial biogenesis but downregulates pyruvate carboxylase in adipocytes: role for triglyceride content reduction
Published in American journal of physiology: endocrinology and metabolism (01-05-2012)“…In adipocytes, mitochondrial uncoupling is known to trigger a triglyceride loss comparable with the one induced by TNFα, a proinflammatory cytokine. However,…”
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Paracrine nitric oxide induces expression of cardiac sarcomeric proteins in adult progenitor cells through soluble guanylyl cyclase/cyclic-guanosine monophosphate and Wnt/β-catenin inhibition
Published in Cardiovascular research (01-10-2016)“…Cardiac progenitor cells (CPC) from adult hearts can differentiate to several cell types composing the myocardium but the underlying molecular pathways are…”
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Dnmt3a-mediated inhibition of Wnt in cardiac progenitor cells improves differentiation and remote remodeling after infarction
Published in JCI insight (15-06-2017)“…Adult cardiac progenitor cells (CPCs) display a low capacity to differentiate into cardiomyocytes in injured hearts, strongly limiting the regenerative…”
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Changes of Metabolic Phenotype of Cardiac Progenitor Cells During Differentiation: Neutral Effect of Stimulation of AMP-Activated Protein Kinase
Published in Stem cells and development (15-11-2019)“…Cardiac progenitor cells (CPCs) in the adult mammalian heart, as well as exogenous CPCs injected at the border zone of infarcted tissue, display very low…”
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Mitochondrial biogenesis in mtDNA-depleted cells involves a Ca super(2+)-dependent pathway and a reduced mitochondrial protein import
Published in The FEBS journal (01-10-2005)“…Alterations in mitochondrial activity resulting from defects in mitochondrial DNA (mtDNA) can modulate the biogenesis of mitochondria by mechanisms that are…”
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Journal Article -
12
Mild mitochondrial uncoupling induces 3T3-L1 adipocyte de-differentiation by a PPARgamma-independent mechanism, whereas TNFalpha-induced de-differentiation is PPARgamma dependent
Published in Journal of cell science (01-01-2009)“…Impairment of mitochondrial activity affects lipid-metabolizing tissues and mild mitochondrial uncoupling has been proposed as a possible strategy to fight…”
Get full text
Journal Article -
13
Mitochondrial biogenesis in mtDNA‐depleted cells involves a Ca 2+ ‐dependent pathway and a reduced mitochondrial protein import
Published in The FEBS journal (01-10-2005)“…Alterations in mitochondrial activity resulting from defects in mitochondrial DNA (mtDNA) can modulate the biogenesis of mitochondria by mechanisms that are…”
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Journal Article -
14
Mitochondrial dysfunction induces triglyceride accumulation in 3T3-L1 cells: role of fatty acid {szligbeta}-oxidation and glucose
Published in Journal of lipid research (2005)“…Mitochondrial cytopathy has been associated with modifications of lipid metabolism in various situations, such as the acquisition of an abnormal adipocyte…”
Get full text
Journal Article