Search Results - "De Paula, Heberth"

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    Effects of brown and golden flaxseed on the lipid profile, glycemia, inflammatory biomarkers, blood pressure and body composition in overweight adolescents by Machado, Adriane M., M.Sc, de Paula, Heberth, D.Sc, Cardoso, Luciane Daniele, D.Sc, Costa, Neuza M.B., Ph.D

    “…Abstract Background Flaxseed is a promising alternative to reduce the risk of diseases associated with body weight excess because it is rich in a-linolenic…”
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    Journal Article
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    Synthesis of Coumarin Derivatives as Versatile Scaffolds for GSK-3β Enzyme Inhibition by Francisco, Carla S, Javarini, Clara L, de S Barcelos, Iatahanderson, Morais, Pedro A B, de Paula, Heberth, de S Borges, Warley, Neto, Álvaro Cunha, Lacerda, Valdemar

    Published in Current topics in medicinal chemistry (01-01-2020)
    “…Glycogen synthase kinase-3 (GSK-3) is involved in the phosphorylation and inactivation of glycogen synthase. GSK-3 inhibitors have been associated with a…”
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    Evaluation of biological and biochemical quality of whey protein by Haraguchi, Fabiano Kenji, Pedrosa, Maria Lucia, Paula, Heberth de, Santos, Rinaldo Cardoso dos, Silva, Marcelo Eustáquio

    Published in Journal of medicinal food (01-12-2010)
    “…Nutritional and biochemical properties of noncommercial whey protein have been described since 1950. However, comparisons between commercial whey protein for…”
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    Journal Article
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    Topomer-CoMFA proposed as a tool to construct dual EGFR/HER-2 models by de Paula, Heberth, Angelo, Rafaela Molina, Honorio, Kathia Maria

    Published in Journal of molecular modeling (01-09-2021)
    “…Protein kinases (in this case, HER-2 and EGFR) are involved in cancer-related diseases. Some reports have shown unique CoMFA models using the sum of activities…”
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    Studies on the Dual Activity of EGFR and HER-2 Inhibitors Using Structure-Based Drug Design Techniques by de Angelo, Rafaela Molina, Almeida, Michell de Oliveira, de Paula, Heberth, Honorio, Kathia Maria

    “…HER-2 and EGFR are biological targets related to the development of cancer and the discovery and/or development of a dual inhibitor could be a good strategy to…”
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    Iron overload in hypercholesterolemic rats affects iron homeostasis and serum lipids but not blood pressure by Turbino-Ribeiro, Silvana M L, Silva, Marcelo E, Chianca, Jr, Deoclécio A, De Paula, Heberth, Cardoso, Leonardo M, Colombari, Eduardo, Pedrosa, Maria Lucia

    Published in The Journal of nutrition (01-01-2003)
    “…Epidemiologic and experimental data suggest that excess iron may contribute to the development of cardiovascular diseases (CVD). Because increased LDL…”
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    Drug design of new 5-HT6 antagonists: a QSAR study of arylsulfonamide derivatives by da Silva, Aldineia P., de Angelo, Rafaela M., de Paula, Heberth, Honório, Kathia M., da Silva, Albérico B. F.

    Published in Structural chemistry (01-08-2020)
    “…Several studies underscore that the 5-hydroxytryptamine subtype 6 (5-HT 6 ) receptor is intrinsically related to the onset of Alzheimer’s disease and its…”
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    Opening the door to the development of novel Abl kinase inhibitors by Bezerra Morais, Pedro Alves, Daltoé, Renata Dalmaschio, Paula, Heberth de

    Published in Future medicinal chemistry (01-11-2016)
    “…The discovery of the importance of kinase activity and its relationship to the emergence and proliferation of cancer cells, due to changes in normal…”
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    Iron overload alters glucose homeostasis, causes liver steatosis, and increases serum triacylglycerols in rats by Silva, Maísa, Silva, Marcelo E, de Paula, Heberth, Carneiro, Cláudia Martins, Pedrosa, Maria Lucia

    Published in Nutrition research (New York, N.Y.) (01-06-2008)
    “…Abstract The objective of this study was to investigate the effect of iron overload with a hyperlipidemic diet on the histologic feature of hepatic tissue, the…”
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