Search Results - "De Paul, Ana Lucia"
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Architects of Pituitary Tumour Growth
Published in Frontiers in endocrinology (Lausanne) (28-06-2022)“…The pituitary is a master gland responsible for the modulation of critical endocrine functions. Pituitary neuroendocrine tumours (PitNETs) display a…”
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Editorial: Architects of Endocrine-Related Tumour Growth
Published in Frontiers in endocrinology (Lausanne) (24-10-2022)Get full text
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Neuronal ceroid lipofuscinosis in the South American-Caribbean region: An epidemiological overview
Published in Frontiers in neurology (12-08-2022)“…Neuronal ceroid lipofuscinoses (NCLs) comprise 13 hereditary neurodegenerative pathologies of very low frequency that affect individuals of all ages around the…”
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Evidence of cellular senescence during the development of estrogen-induced pituitary tumors
Published in Endocrine-related cancer (01-06-2015)“…Although pituitary adenomas represent 25% of intracranial tumors, they are usually benign, with the mechanisms by which these tumors usually avoid an invasive…”
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Bromocriptine induces parapoptosis as the main type of cell death responsible for experimental pituitary tumor shrinkage
Published in Toxicology and applied pharmacology (01-10-2009)“…Bromocriptine (Bc) produces pituitary tumoral mass regression which induces the cellular death that was classically described as apoptosis. However, recent…”
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Subcellular localisation of VEGF in different pituitary cells. Changes of its expression in oestrogen induced prolactinomas
Published in Journal of Molecular Histology (01-10-2005)“…Vascular endothelial growth factor (VEGF) is an important angiogenic factor in the pituitary gland. The objective of this study was to unveil the VEGF…”
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The neuronal ceroid lipofuscinosis‐related protein CLN8 regulates endo‐lysosomal dynamics and dendritic morphology
Published in Biology of the cell (01-10-2021)“…Background Information The endo‐lysosomal system (ELS) comprises a set of membranous organelles responsible for transporting intracellular and extracellular…”
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Toll-Like Receptor 4 in Rat Prostate: Modulation by Testosterone and Acute Bacterial Infection in Epithelial and Stromal Cells
Published in Biology of reproduction (01-11-2006)“…The prostate gland is the most inflammation-prone organ in the male reproductive tract. However, little information is available regarding the immunobiology of…”
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Neuropeptide glutamic-isoleucine (NEI) specifically stimulates the secretory activity of gonadotrophs in primary cultures of female rat pituitary cells
Published in Peptides (New York, N.Y. : 1980) (01-11-2009)“…The neuropeptide EI (NEI) is derived from proMCH. It activates GnRH neurons, and has been shown to stimulate the LH release following intracerebroventricular…”
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Anti-glioma properties of DVL, a lectin purified from Dioclea violacea
Published in International journal of biological macromolecules (01-12-2018)“…Plant lectins have been studied owing to their structural properties and biological effects that include agglutinating activity, antidepressant-like effect and…”
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Chronic Metabolic Derangement-Induced Cognitive Deficits and Neurotoxicity Are Associated with REST Inactivation
Published in Molecular neurobiology (01-03-2019)“…Chronic metabolic alterations may represent a risk factor for the development of cognitive impairment, dementia, or neurodegenerative diseases. Hyperglycemia…”
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Sellar xanthogranuloma as a diagnostic challenge: a report on five cases
Published in Frontiers in neuroscience (22-09-2023)“…Xanthogranulomas are considered rare tumors, with their sellar and non-sellar frequency ranging from 1.6 to 7% among intracranial lesions, and described as a…”
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Trastuzumab inhibits pituitary tumor cell growth modulating the TGFB/SMAD2/3 pathway
Published in Endocrine-related cancer (01-10-2018)“…In pituitary adenomas, early recurrences and resistance to conventional pharmacotherapies are common, but the mechanisms involved are still not understood. The…”
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Uric acid activates NRLP3 inflammasome in an in-vivo model of epithelial to mesenchymal transition in the kidney
Published in Journal of molecular histology (01-06-2017)“…Uric acid (UA) has been associated with renal fibrosis and progression of chronic kidney disease. However, the underlying mechanisms of this process have still…”
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Diphenyl diselenide administration enhances cortical mitochondrial number and activity by increasing hemeoxygenase type 1 content in a methylmercury-induced neurotoxicity mouse model
Published in Molecular and cellular biochemistry (01-05-2014)“…Interest in biochemistry of organoselenium compound has increased in the last decades, mainly due to their chemical and biological activities. Here, we…”
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Testosterone abrogates TLR4 activation in prostate smooth muscle cells contributing to the preservation of a differentiated phenotype
Published in Journal of cellular physiology (01-07-2013)“…Prostate smooth muscle cells (pSMCs) are capable of responding to inflammatory stimuli by secreting proinflammatory products, which causes pSMCs to undergo…”
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Involvement of MEK/ERK1/2 and PI3K/Akt Pathways in the Refractory Behavior of GH3B6 Pituitary Tumor Cells to the Inhibitory Effect of TGFβ1
Published in Endocrinology (Philadelphia) (01-02-2015)“…Pituitary tumor cells have a poor response to the growth inhibitory effect of TGFβ1, possibly resulting from the cross talk of TGFβ/Smads signal with other…”
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Functional Toll-like receptor 4 expressed in lactotrophs mediates LPS-induced proliferation in experimental pituitary hyperplasia
Published in Experimental cell research (15-11-2013)“…Toll like receptor 4 (TLR4) has been characterized for its ability to recognize bacterial endotoxin lipopolysaccharide (LPS). Considering that infections or…”
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“Atypical” Phenotypes of Neuronal Ceroid Lipofuscinosis: The Argentine Experience in the Genomic Era
Published in Journal of inborn errors of metabolism and screening (2021)“…ABSTRACT Neuronal Ceroid Lipofuscinosis (NCL) refers to a group of inherited lysosomal storage disorders characterized by the intracellular accumulation of…”
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Thyroid tumor cells-fibroblasts crosstalk: role of extracellular vesicles
Published in Endocrine Connections (01-06-2020)“…Tumor-stroma crosstalk leads to a tumor-promoting microenvironment. In this milieu, extracellular vesicles (EVs) are protagonists in cell-cell communication…”
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