Search Results - "De Pas, T."

A microbial consortium couples anaerobic methane oxidation to denitrification by Strous, Marc, Raghoebarsing, Ashna A, Pol, Arjan, Rijpstra, W. Irene C, Damsté, Jaap S. Sinninghe, Smolders, Alfons J. P, Jetten, Mike S. M, Op den Camp, Huub J. M, van de Pas-Schoonen, Katinka T, Ettwig, Katharina F, Schouten, Stefan

“…Modern agriculture has accelerated biological methane and nitrogen cycling on a global scale. Freshwater sediments often receive increased downward fluxes of…”
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Grading the neuroendocrine tumors of the lung: an evidence-based proposal by Rindi, G, Klersy, C, Inzani, F, Fellegara, G, Ampollini, L, Ardizzoni, A, Campanini, N, Carbognani, P, De Pas, T M, Galetta, D, Granone, P L, Righi, L, Rusca, M, Spaggiari, L, Tiseo, M, Viale, G, Volante, M, Papotti, M, Pelosi, G

“…Lung neuroendocrine tumors are catalogued in four categories by the World Health Organization (WHO 2004) classification. Its reproducibility and prognostic…”
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Denitrifying bacteria anaerobically oxidize methane in the absence of Archaea by Ettwig, Katharina F., Shima, Seigo, Van De Pas‐Schoonen, Katinka T., Kahnt, Jörg, Medema, Marnix H., Op Den Camp, Huub J. M., Jetten, Mike S. M., Strous, Marc

“…Summary Recently, a microbial consortium was shown to couple the anaerobic oxidation of methane to denitrification, predominantly in the form of nitrite…”
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Missing lithotroph identified as new planctomycete by Jetten, Mike S. M, Strous, Marc, Fuerst, John A, Kramer, Evelien H. M, Logemann, Susanne, Muyzer, Gerard, van de Pas-Schoonen, Katinka T, Webb, Richard, Kuenen, J. Gijs

“…With the increased use of chemical fertilizers in agriculture, many densely populated countries face environmental problems associated with high ammonia…”
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Adjuvant radiotherapy treatment for soft tissue sarcoma of extremities and trunk. A retrospective mono-institutional analysis by Spoto, R, Vavassori, A, Dicuonzo, S, Pepa, M, Volpe, S, Alessandro, O, Gandini, S, Di Venosa, B, Miglietta, E, Fodor, C, Orsolini, G Marco, Prestianni, P, Cattani, F, Comi, S, Lazzari, R, Renne, G, De Pas, T, Orecchia, R, Pennacchioli, E, Jereczek-Fossa, B Alicja

“…Soft tissue sarcomas (STS) are uncommon, heterogeneous malignant tumors of mesodermal origin. Other than conservative surgery (CS), neoadjuvant or adjuvant…”
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Phase II, open-label study of PTK787/ZK222584 for the treatment of metastatic gastrointestinal stromal tumors resistant to imatinib mesylate by Joensuu, H., De Braud, F., Coco, P., De Pas, T., Putzu, C., Spreafico, C., Bono, P., Bosselli, S., Jalava, T., Laurent, D., Casali, P. G.

“…Background: We evaluated safety and efficacy of PTK787/ZK222584 (PTK/ZK), a novel tyrosine kinase inhibitor of KIT, platelet-derived growth factor receptors…”
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A randomized phase II study of the MEK1/MEK2 inhibitor trametinib (GSK1120212) compared with docetaxel in KRAS-mutant advanced non-small-cell lung cancer (NSCLC) by Blumenschein, G.R., Smit, E.F., Planchard, D., Kim, D.-W., Cadranel, J., De Pas, T., Dunphy, F., Udud, K., Ahn, M.-J., Hanna, N.H., Kim, J.-H., Mazieres, J., Kim, S.-W., Baas, P., Rappold, E., Redhu, S., Puski, A., Wu, F.S., Jänne, P.A.

“…KRAS mutations in non-small-cell lung cancer (NSCLC) are associated with poor prognosis. Trametinib, a selective inhibitor of MEK1/MEK2, demonstrated similar…”
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Enrichment and Molecular Detection of Denitrifying Methanotrophic Bacteria of the NC10 Phylum by Ettwig, Katharina F, van Alen, Theo, van de Pas-Schoonen, Katinka T, Jetten, Mike S.M, Strous, Marc

“…Anaerobic methane oxidation coupled to denitrification was recently assigned to bacteria belonging to the uncultured phylum NC10. In this study, we incubated…”
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Expression of gemcitabine- and cisplatin-related genes in non-small-cell lung cancer by Toffalorio, F, Giovannetti, E, De Pas, T, Radice, D, Pelosi, G, Manzotti, M, Minocci, D, Spaggiari, L, Spitaleri, G, Noberasco, C, Catania, C, Boselli, S, Danesi, R, de Braud, F

“…The aim of this study was to investigate the influence of histology and site of analysis (primary tumor versus lymph node) on the expression of genes involved…”
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Thymic carcinoma with Lynch syndrome or microsatellite instability, a rare entity responsive to immunotherapy by Repetto, M., Conforti, F., Pirola, S., Calvello, M., Pala, L., Bonanni, B., Catania, C., Curigliano, G., De Pas, T.

“…Thymic carcinoma (TC) is a rare aggressive tumour occurring in adults characterised by one of the lowest tumor mutational burdens (TMB). Microsatellite…”
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Sex-based differences of the tumor mutational burden and T-cell inflammation of the tumor microenvironment by Conforti, F., Pala, L., Bagnardi, V., Viale, G., De Pas, T., Pagan, E., Gelber, R.D., Goldhirsch, A.

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Nitrite-driven anaerobic methane oxidation by oxygenic bacteria by Ettwig, Katharina F, Strous, Marc, Butler, Margaret K, Le Paslier, Denis, Pelletier, Eric, Mangenot, Sophie, Kuypers, Marcel M. M, Schreiber, Frank, Dutilh, Bas E, Zedelius, Johannes, de Beer, Dirk, Gloerich, Jolein, Wessels, Hans J. C. T, van Alen, Theo, Luesken, Francisca, Wu, Ming L, van de Pas-Schoonen, Katinka T, Op den Camp, Huub J. M, Janssen-Megens, Eva M, Francoijs, Kees-Jan, Stunnenberg, Henk, Weissenbach, Jean, Jetten, Mike S. M

“…Only three biological pathways are known to produce oxygen: photosynthesis, chlorate respiration and the detoxification of reactive oxygen species. Here we…”
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A phase I, dose-escalation study of volasertib combined with nintedanib in advanced solid tumors by de Braud, F., Cascinu, S., Spitaleri, G., Pilz, K., Clementi, L., Liu, D., Sikken, P., De Pas, T.

“…Volasertib is a potent and selective cell-cycle kinase inhibitor that induces mitotic arrest and apoptosis by targeting Polo-like kinases. This study…”
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Sex-based differences in response to anti-PD-1 or PD-L1 treatment in patients with non-small-cell lung cancer expressing high PD-L1 levels. A systematic review and meta-analysis of randomized clinical trials by Conforti, F., Pala, L., Pagan, E., Corti, C., Bagnardi, V., Queirolo, P., Catania, C., De Pas, T., Giaccone, G.

“…In our previous works, we demonstrated that patients’ sex affects the efficacy of immune checkpoint inhibitors (ICIs) in patients with several advanced solid…”
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Erratum to “Lung cancer” [Crit. Rev. Oncol./Hematol. 27 (February (2)) (1998) 133–134] by Repetto, L., Granetto, C., Venturino, A., de Pas, T., Giacone, G.

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Life-threatening toxic epidermal necrolysis during voriconazole therapy for invasive aspergillosis after chemotherapy by Curigliano, G., Formica, V., De Pas, T., Spitaleri, G., Pietri, E., Fazio, N., de Braud, F., Goldhirsch, A.

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Deciphering the evolution and metabolism of an anammox bacterium from a community genome by Jetten, Mike S. M, Wagner, Michael, Strous, Marc, Pelletier, Eric, Mangenot, Sophie, Rattei, Thomas, Lehner, Angelika, Taylor, Michael W, Horn, Matthias, Daims, Holger, Bartol-Mavel, Delphine, Wincker, Patrick, Barbe, Valérie, Fonknechten, Nuria, Vallenet, David, Segurens, Béatrice, Schenowitz-Truong, Chantal, Médigue, Claudine, Collingro, Astrid, Snel, Berend, Dutilh, Bas E, Op den Camp, Huub J. M, van der Drift, Chris, Cirpus, Irina, van de Pas-Schoonen, Katinka T, Harhangi, Harry R, van Niftrik, Laura, Schmid, Markus, Keltjens, Jan, van de Vossenberg, Jack, Kartal, Boran, Meier, Harald, Frishman, Dmitrij, Huynen, Martijn A, Mewes, Hans-Werner, Weissenbach, Jean, Le Paslier, Denis

“…Anaerobic ammonium oxidation (anammox) has become a main focus in oceanography and wastewater treatment. It is also the nitrogen cycle's major remaining…”
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Drug distribution and pharmacokinetic/pharmacodynamic relationship of paclitaxel and gemcitabine in patients with non-small-cell lung cancer by Fogli, S., Danesi, R., De Braud, F., De Pas, T., Curigliano, G., Giovannetti, E., Tacca, M. Del

“…Summary Background Gemcitabine and paclitaxel are two of the most active agents in non-small-cell lung cancer (NSCLC), and pharmacologic investigation of the…”
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Vatalanib for metastatic gastrointestinal stromal tumour (GIST) resistant to imatinib: final results of a phase II study by Joensuu, H, De Braud, F, Grignagni, G, De Pas, T, Spitalieri, G, Coco, P, Spreafico, C, Boselli, S, Toffalorio, F, Bono, P, Jalava, T, Kappeler, C, Aglietta, M, Laurent, D, Casali, P G

“…Background: Vatalanib (PTK787/ZK 222584) inhibits a few tyrosine kinases including KIT, platelet-derived growth factor receptors (PDGFRs) and vascular…”
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Imatinib administration in two patients with liver metastases from GIST and severe jaundice by DE PAS, T, DANESI, R, CATANIA, C, CURIGLIANO, G, DE BRAUD, F

“…Imatinib is the only effective and approved systemic therapy for the treatment of patients with advanced gastrointestinal stromal tumours (GISTs). Although…”
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