Search Results - "De Paepe, Monique"

Examination of the twin placenta by Paepe, Monique E. De, MD

“…Abstract Twin birth rates have increased dramatically over the past three decades, and twins currently account for 3% of all pregnancies. Twin pregnancies of…”
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Galectin-3 expression and effect of supplementation in neonatal mice with disseminated Candida albicans infection by Verma, Prasoon, Laforce-Nesbitt, Sonia S., Tucker, Richard, Mao, Quanfu, De Paepe, Monique E., Bliss, Joseph M.

“…Background Invasive candidiasis is an important cause of fungal infections in immunocompromised patients, including premature infants. The S-type lectin,…”
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Timing and cell specificity of senescence drives postnatal lung development and injury by Yao, Hongwei, Wallace, Joselynn, Peterson, Abigail L., Scaffa, Alejandro, Rizal, Salu, Hegarty, Katy, Maeda, Hajime, Chang, Jason L., Oulhen, Nathalie, Kreiling, Jill A., Huntington, Kelsey E., De Paepe, Monique E., Barbosa, Guilherme, Dennery, Phyllis A.

“…Senescence causes age-related diseases and stress-related injury. Paradoxically, it is also essential for organismal development. Whether senescence…”
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Involvement of miRNA-34a regulated Krüppel-like factor 4 expression in hyperoxia-induced senescence in lung epithelial cells by Maeda, Hajime, Yao, Hongwei, Go, Hayato, Huntington, Kelsey E, De Paepe, Monique E, Dennery, Phyllis A

“…Premature infants, subjected to supplemental oxygen and mechanical ventilation, may develop bronchopulmonary dysplasia, a chronic lung disease characterized by…”
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Herpes virus entry mediator signaling blockade produces mortality in neonatal sepsis through induced cardiac dysfunction by Wakeley, Michelle E, Denning, Naomi-Liza, Jiang, Jihong, De Paepe, Monique E, Chung, Chun-Shiang, Wang, Ping, Ayala, Alfred

“…Sepsis remains a major source of morbidity and mortality in neonates, and characterization of immune regulation in the neonatal septic response remains…”
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Single-cell transcriptomics reveals lasting changes in the lung cellular landscape into adulthood after neonatal hyperoxic exposure by Scaffa, Alejandro, Yao, Hongwei, Oulhen, Nathalie, Wallace, Joselynn, Peterson, Abigail L., Rizal, Salu, Ragavendran, Ashok, Wessel, Gary, De Paepe, Monique E., Dennery, Phyllis A.

“…Ventilatory support, such as supplemental oxygen, used to save premature infants impairs the growth of the pulmonary microvasculature and distal alveoli,…”
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Survival and Pulmonary Injury After Neonatal Sepsis: PD1/PDL1's Contributions to Mouse and Human Immunopathology by Fallon, Eleanor A, Chung, Chun-Shiang, Heffernan, Daithi S, Chen, Yaping, De Paepe, Monique E, Ayala, Alfred

“…Morbidity and mortality associated with neonatal sepsis remains a healthcare crisis. PD1 neonatal mice endured experimental sepsis, in the form of cecal slurry…”
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Ex vivo expanded human cord blood-derived hematopoietic progenitor cells induce lung growth and alveolarization in injured newborn lungs by Mao, Quanfu, Chu, Sharon, Ghanta, Sailaja, Padbury, James F, De Paepe, Monique E

“…We investigated the capacity of expanded cord blood-derived CD34+ hematopoietic progenitor cells to undergo respiratory epithelial differentiation ex vivo, and…”
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Galectin-3 plays an important role in protection against disseminated candidiasis by Linden, Jennifer R., De Paepe, Monique E., Laforce-Nesbitt, Sonia S., Bliss, Joseph M.

“…Abstract Recent in vitro studies have implicated galectin-3 as an important receptor in host recognition and response to specific Candida species; however, its…”
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Endoglin (CD105) Up-regulation in Pulmonary Microvasculature of Ventilated Preterm Infants by De Paepe, Monique E, Patel, Chintan, Tsai, Amy, Gundavarapu, Sravanthi, Mao, Quanfu

“…Preterm infants exposed to mechanical ventilation and oxygen are at risk for bronchopulmonary dysplasia (BPD), a multifactorial chronic lung disorder…”
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Growth of Pulmonary Microvasculature in Ventilated Preterm Infants by De Paepe, Monique E, Mao, Quanfu, Powell, Jessica, Rubin, Sam E, DeKoninck, Philip, Appel, Naomi, Dixon, Meredith, Gundogan, Fusun

“…Density-based morphometric studies have demonstrated decreased capillary density in infants with bronchopulmonary dysplasia (BPD) and in BPD-like animal…”
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The pentose phosphate pathway mediates hyperoxia-induced lung vascular dysgenesis and alveolar simplification in neonates by Gong, Jiannan, Feng, Zihang, Peterson, Abigail L, Carr, Jennifer F, Lu, Xuexin, Zhao, Haifeng, Ji, Xiangming, Zhao, You-Yang, De Paepe, Monique E, Dennery, Phyllis A, Yao, Hongwei

“…Dysmorphic pulmonary vascular growth and abnormal endothelial cell (EC) proliferation are paradoxically observed in premature infants with bronchopulmonary…”
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Placental SARS-CoV-2 distribution correlates with level of tissue oxygenation in COVID-19-associated necrotizing histiocytic intervillositis/perivillous fibrin deposition by Mao, Quanfu, Chu, Sharon, Shapiro, Svetlana, Young, Lawrence, Russo, Melissa, De Paepe, Monique E.

“…Recent evidence supports the – rare – occurrence of vertical transplacental SARS-CoV-2 transmission. We previously determined that placental expression of…”
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Xenotransplantation of human fetal adipose tissue: a model of in vivo adipose tissue expansion and adipogenesis by Garcia, Briana, Francois-Vaughan, Heather, Onikoyi, Omobola, Kostadinov, Stefan, De Paepe, Monique E., Gruppuso, Philip A., Sanders, Jennifer A.

“…Obesity during childhood and beyond may have its origins during fetal or early postnatal life. At present, there are no suitable in vivo experimental models to…”
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Intrauterine demise due to congenital mesoblastic nephroma in a fetus conceived by assisted reproductive technology by De Paepe, Monique E., M.D, Shapiro, Svetlana, M.D, Young, Lawrence, B.Sc, Carr, Stephen R., M.D, Gundogan, Fusun, M.D

“…Objective To report a case of antenatally diagnosed congenital mesoblastic nephroma in an assisted reproductive technology (ART) conception. Design Case…”
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Increased placental expression of angiotensin-converting enzyme 2, the receptor of SARS-CoV-2, associated with hypoxia in twin anemia-polycythemia sequence (TAPS) by Mao, Quanfu, Chu, Sharon, Shapiro, Svetlana, Bliss, Joseph M., De Paepe, Monique E.

“…Recent reports suggest SARS-CoV-2, the virus causing COVID-19, may be transmittable from pregnant mother to placenta and fetus, albeit rarely. The efficacy of…”
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Discordant placental oxygenation and autophagy in twin anemia-polycythemia sequence (TAPS) by Mao, Quanfu, Chu, Sharon, Shapiro, Svetlana, Yao, Hongwei, De Paepe, Monique E.

“…(Macro)autophagy is an important process of self-degradation of macromolecules and organelles that ensures cellular homeostasis and energy preservation during…”
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Extensive Placental Choriovascular Infiltration by Maturing Myeloid Cells in down Syndrome-Associated Transient Abnormal Myelopoiesis by Ravishankar, Sanjita, Hoffman, Laurie, Lertsburapa, Terakeith, Welch, Jennifer, Treaba, Diana, De Paepe, Monique E.

“…Transient abnormal myelopoiesis (TAM), a clonal proliferation of predominantly megakaryocytic precursor cells, affects 4%–10% of newborns with Down syndrome…”
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Intranasal versus Intraperitoneal Delivery of Human Umbilical Cord Tissue–Derived Cultured Mesenchymal Stromal Cells in a Murine Model of Neonatal Lung Injury by Liu, Liansheng, Mao, Quanfu, Chu, Sharon, Mounayar, Marwan, Abdi, Reza, Fodor, William, Padbury, James F, De Paepe, Monique E

“…Clinical trials investigating mesenchymal stromal cell (MSC) therapy for bronchopulmonary dysplasia have been initiated; however, the optimal delivery route…”
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Preexisting maternal immunity to AAV but not Cas9 impairs in utero gene editing in mice by Riley, John S, Luks, Valerie L, Berkowitz, Cara L, Dumitru, Ana Maria, Kus, Nicole J, Dave, Apeksha, Menon, Pallavi, De Paepe, Monique E, Jain, Rajan, Li, Li, Dugoff, Lorraine, Teefey, Christina Paidas, Alameh, Mohamad-Gabriel, Zoltick, Philip W, Peranteau, William H

“…In utero gene editing (IUGE) is a potential treatment for inherited diseases that cause pathology before or soon after birth. Preexisting immunity to…”
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