Search Results - "De Oliveira, Satiro"

Acoustofluidic sonoporation for gene delivery to human hematopoietic stem and progenitor cells by Belling, Jason N., Heidenreich, Liv K., Tian, Zhenhua, Mendoza, Alexandra M., Chiou, Tzu-Ting, Gong, Yao, Chen, Natalie Y., Young, Thomas D., Wattanatorn, Natcha, Park, Jae Hyeon, Scarabelli, Leonardo, Chiang, Naihao, Takahashi, Jack, Young, Stephen G., Stieg, Adam Z., De Oliveira, Satiro, Huang, Tony Jun, Weiss, Paul S., Jonas, Steven J.

“…Advances in gene editing are leading to new medical interventions where patients’ own cells are used for stem cell therapies and immunotherapies. One of the…”
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In Vitro Generation of Human NK Cells Expressing Chimeric Antigen Receptor Through Differentiation of Gene-Modified Hematopoietic Stem Cells by Lowe, Emily, Truscott, Laurel C, De Oliveira, Satiro N

“…NK cells represent a very promising source for adoptive cellular approaches for cancer immunotherapy, and extensive research has been conducted, including…”
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Antiviral cellular therapy for enhancing T-cell reconstitution before or after hematopoietic stem cell transplantation (ACES): a two-arm, open label phase II interventional trial of pediatric patients with risk factor assessment by Keller, Michael D., Hanley, Patrick J., Chi, Yueh-Yun, Aguayo-Hiraldo, Paibel, Dvorak, Christopher C., Verneris, Michael R., Kohn, Donald B., Pai, Sung-Yun, Dávila Saldaña, Blachy J., Hanisch, Benjamin, Quigg, Troy C., Adams, Roberta H., Dahlberg, Ann, Chandrakasan, Shanmuganathan, Hasan, Hasibul, Malvar, Jemily, Jensen-Wachspress, Mariah A., Lazarski, Christopher A., Sani, Gelina, Idso, John M., Lang, Haili, Chansky, Pamela, McCann, Chase D., Tanna, Jay, Abraham, Allistair A., Webb, Jennifer L., Shibli, Abeer, Keating, Amy K., Satwani, Prakash, Muranski, Pawel, Hall, Erin, Eckrich, Michael J., Shereck, Evan, Miller, Holly, Mamcarz, Ewelina, Agarwal, Rajni, De Oliveira, Satiro N., Vander Lugt, Mark T., Ebens, Christen L., Aquino, Victor M., Bednarski, Jeffrey J., Chu, Julia, Parikh, Suhag, Whangbo, Jennifer, Lionakis, Michail, Zambidis, Elias T., Gourdine, Elizabeth, Bollard, Catherine M., Pulsipher, Michael A.

“…Viral infections remain a major risk in immunocompromised pediatric patients, and virus-specific T cell (VST) therapy has been successful for treatment of…”
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A CD19/Fc fusion protein for detection of anti-CD19 chimeric antigen receptors by De Oliveira, Satiro N, Wang, Jiexin, Ryan, Christine, Morrison, Sherie L, Kohn, Donald B, Hollis, Roger P

“…Chimeric Antigen Receptors (CARs) consist of the antigen-recognition portion of a monoclonal antibody fused to an intracellular signaling domain capable of…”
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Mediport use as an acceptable standard for CAR T cell infusion by Eylon, Maya, Prabhu, Snehit, John, Samuel, King, Maxwell J M, Bhatt, Dhruv, Curran, Kevin J, Erickson, Courtney, Karras, Nicole A, Phillips, Christine L, Satwani, Prakash, Hermiston, Michelle, Southworth, Erica, Baumeister, Susanne H C, Talano, Julie-An, MacMillan, Margaret L, Rossoff, Jenna, Bonifant, Challice L, Myers, Gary Doug, Rouce, Rayne H, Toner, Keri, Driscoll, Timothy A, Katsanis, Emmanuel, Salzberg, Dana B, Schiff, Deborah, De Oliveira, Satiro N, Capitini, Christian M, Pacenta, Holly L, Pfeiffer, Thomas, Shah, Niketa C, Huynh, Van, Skiles, Jodi L, Fraint, Ellen, McNerney, Kevin O, Quigg, Troy C, Krueger, Joerg, Ligon, John A, Fabrizio, Vanessa A, Baggott, Christina, Laetsch, Theodore W, Schultz, Liora M

“…Mediport use as a clinical option for the administration of chimeric antigen receptor T cell (CAR T cell) therapy in patients with B-cell malignancies has yet…”
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Pre-clinical development of gene modification of haematopoietic stem cells with chimeric antigen receptors for cancer immunotherapy by Larson, Sarah M., Truscott, Laurel C., Chiou, Tzu-Ting, Patel, Amie, Kao, Roy, Tu, Andy, Tyagi, Tulika, Lu, Xiang, Elashoff, David, De Oliveira, Satiro N.

“…Patients with refractory or recurrent B-lineage hematologic malignancies have less than 50% of chance of cure despite intensive therapy and innovative…”
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Hematopoietic Stem-Cell Gene Therapy for Cerebral Adrenoleukodystrophy by Eichler, Florian, Duncan, Christine, Musolino, Patricia L, Orchard, Paul J, De Oliveira, Satiro, Thrasher, Adrian J, Armant, Myriam, Dansereau, Colleen, Lund, Troy C, Miller, Weston P, Raymond, Gerald V, Sankar, Raman, Shah, Ami J, Sevin, Caroline, Gaspar, H. Bobby, Gissen, Paul, Amartino, Hernan, Bratkovic, Drago, Smith, Nicholas J.C, Paker, Asif M, Shamir, Esther, O’Meara, Tara, Davidson, David, Aubourg, Patrick, Williams, David A

“…Among boys with cerebral adrenoleukodystrophy, matched donors for allogeneic transplantation are available to only a few. Infusion of CD34+ autologous stem…”
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Use of Rapamycin in a Patient With Juvenile Myelomonocytic Leukemia: A Case Report by Upadhyay, Shivani Y., De Oliveira, Satiro N., Moore, Theodore B.

“…The relapse rate for children with juvenile myelomonocytic leukemia (JMML) status post hematopoietic stem cell transplantation (HSCT) approaches 50% within 5…”
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Hematopoietic stem cells for cancer immunotherapy by Gschweng, Eric, De Oliveira, Satiro, Kohn, Donald B.

“…Summary Hematopoietic stem cells (HSCs) provide an attractive target for immunotherapy of cancer and leukemia by the introduction of genes encoding T‐cell…”
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Site-Specific Gene Editing of Human Hematopoietic Stem Cells for X-Linked Hyper-IgM Syndrome by Kuo, Caroline Y., Long, Joseph D., Campo-Fernandez, Beatriz, de Oliveira, Satiro, Cooper, Aaron R., Romero, Zulema, Hoban, Megan D., Joglekar, Alok V., Lill, Georgia R., Kaufman, Michael L., Fitz-Gibbon, Sorel, Wang, Xiaoyan, Hollis, Roger P., Kohn, Donald B.

“…X-linked hyper-immunoglobulin M (hyper-IgM) syndrome (XHIM) is a primary immunodeficiency due to mutations in CD40 ligand that affect immunoglobulin…”
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A Cetuximab-Mediated Suicide System in Chimeric Antigen Receptor-Modified Hematopoietic Stem Cells for Cancer Therapy by Kao, Roy L, Truscott, Laurel C, Chiou, Tzu-Ting, Tsai, Wenting, Wu, Anna M, De Oliveira, Satiro N

“…Using gene modification of hematopoietic stem cells (HSC) to create persistent generation of multilineage immune effectors to target cancer cells directly is…”
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HJV mutations causing hemochromatosis: variable phenotypic expression in a pair of twins by Vadivelan, Akhila, Zhang, Sarah, Srole, Daniel N, Marcus, Elizabeth A, Neto, George Carvalho, Nemeth, Elizabeta, Ganz, Tomas, De Oliveira, Satiro

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Fluorinated Silane-Modified Filtroporation Devices Enable Gene Knockout in Human Hematopoietic Stem and Progenitor Cells by Frost, Isaura M., Mendoza, Alexandra M., Chiou, Tzu-Ting, Kim, Philseok, Aizenberg, Joanna, Kohn, Donald B., De Oliveira, Satiro N., Weiss, Paul S., Jonas, Steven J.

“…Intracellular delivery technologies that are cost-effective, non-cytotoxic, efficient, and cargo-agnostic are needed to enable the manufacturing of cell-based…”
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Lentiviral Gene Therapy for Cerebral Adrenoleukodystrophy by Eichler, Florian, Duncan, Christine N., Musolino, Patricia L., Lund, Troy C., Gupta, Ashish O., De Oliveira, Satiro, Thrasher, Adrian J., Aubourg, Patrick, Kühl, Jörn-Sven, Loes, Daniel J., Amartino, Hernan, Smith, Nicholas, Folloni Fernandes, Juliana, Sevin, Caroline, Sankar, Raman, Hussain, Shaun A., Gissen, Paul, Dalle, Jean-Hugues, Platzbecker, Uwe, Downey, Gerald F., McNeil, Elizabeth, Demopoulos, Laura, Dietz, Andrew C., Thakar, Himal L., Orchard, Paul J., Williams, David A.

“…Thirty-two patients with cerebral adrenoleukodystrophy received lentiviral gene therapy, and after a median of 6 years most were free of major disability…”
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Development of Hematopoietic Stem Cell-Engineered Invariant Natural Killer T Cell Therapy for Cancer by Zhu, Yanni, Smith, Drake J., Zhou, Yang, Li, Yan-Ruide, Yu, Jiaji, Lee, Derek, Wang, Yu-Chen, Di Biase, Stefano, Wang, Xi, Hardoy, Christian, Ku, Josh, Tsao, Tasha, Lin, Levina J., Pham, Alexander T., Moon, Heesung, McLaughlin, Jami, Cheng, Donghui, Hollis, Roger P., Campo-Fernandez, Beatriz, Urbinati, Fabrizia, Wei, Liu, Pang, Larry, Rezek, Valerie, Berent-Maoz, Beata, Macabali, Mignonette H., Gjertson, David, Wang, Xiaoyan, Galic, Zoran, Kitchen, Scott G., An, Dong Sung, Hu-Lieskovan, Siwen, Kaplan-Lefko, Paula J., De Oliveira, Satiro N., Seet, Christopher S., Larson, Sarah M., Forman, Stephen J., Heath, James R., Zack, Jerome A., Crooks, Gay M., Radu, Caius G., Ribas, Antoni, Kohn, Donald B., Witte, Owen N., Yang, Lili

“…Invariant natural killer T (iNKT) cells are potent immune cells for targeting cancer; however, their clinical application has been hindered by their low…”
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Successful engraftment of haploidentical bone marrow with post‐transplantation cyclophosphamide in patients with aplastic anemia by Dang, Brian Norman, De Oliveira, Satiro, Gray, Ashley, Bowles, LaVette, Moore, Theodore Bruce

“…Patients with severe aplastic anemia (SAA) may benefit from hematopoietic stem cell transplantation, but many of them lack a matched donor. Haploidentical…”
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Pediatric hematopoietic cell transplantation: Longitudinal trends in body mass index and outcomes by Dang, Brian Norman, Wilhalme, Holly, Ch'ng, James, De Oliveira, Satiro, Bowles, LaVette, Moore, Theodore Bruce

“…Pediatric recipients of HCT may have a high susceptibility for overweight and obesity, and obesity may negatively impact post‐transplant mortality and…”
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False-positive magnetic resonance imaging findings in follow-up of pediatric patients with tumors of the central nervous system by De Oliveira, Satiro Nakamura, Gonzalez-Gomez, Ignacio, Panigrahy, Ashok, Krieger, Mark, McComb, Gordon, Finlay, Jonathan L, Dhall, Girish

“…Management of patients with central nervous system tumors relies largely on magnetic resonance imaging scans to document disease progression or recurrence. The…”
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Gene-modified hematopoietic stem cells for cancer immunotherapy by Larson, Sarah, De Oliveira, Satiro N

“…The rapid expansion of available cancer immunotherapies has resulted in favorable early outcomes. Specifically the use of gene therapy to introduce chimeric…”
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Same sibling marrow following cord allogeneic transplantation as therapy for second relapse acute promyelocytic leukemia in a pediatric patient by De Oliveira, Satiro N., Kao, Roy L., Pham, Andrew, Smith, LaMarr Taylor, Kempert, Pamela, Moore, Theodore B.

“…Optimal therapy for relapsed APL in pediatric patients is controversial. Allogeneic HSCT is an alternative, with event‐free survival of 70–75%. We report a…”
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