Search Results - "De Moraes, Ana Carolina Rabello"
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Patterns of dendritic cell and monocyte subsets are associated with disease severity and mortality in liver cirrhosis patients
Published in Scientific reports (15-03-2021)“…Liver cirrhosis is often complicated by an immunological imbalance known as cirrhosis-associated immune dysfunction. This study aimed to investigate…”
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Analysis of the presence of FLT3 gene mutation and association with prognostic factors in adult and pediatric acute leukemia patients
Published in Brazilian Journal of Pharmaceutical Sciences (01-01-2017)“…When the FLT3 gene is mutated, it originates a modified receptor with structural changes, which give survival advantage and malignant hematopoietic cell…”
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The relationship between peripheral immune response and disease severity in SARS‐CoV‐2‐infected subjects: A cross‐sectional study
Published in Immunology (01-04-2022)“…Coronavirus disease 2019 (COVID‐19) is a respiratory infection caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) and marked by an intense…”
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Selenylated Imidazo[1,2 -a ]pyridine Induces Cell Senescence and Oxidative Stress in Chronic Myeloid Leukemia Cells
Published in Molecules (Basel, Switzerland) (16-01-2023)“…Imidazo[1,2 ]pyridines (IPs) have been studied regarding drug development. The objective of this work was to evaluate the antileukemic capacity of IP…”
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5
T cell maturation is significantly affected by SARS‐CoV‐2 infection
Published in Immunology (01-07-2023)“…Coronavirus disease 2019 (COVID‐19) is a respiratory tract infection caused by the new severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2). An…”
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6
Chemical profile, antimicrobial potential, and antiaggregant activity of supercritical fluid extract from Agaricus bisporus
Published in Chemical papers (01-10-2022)“…Mushrooms are known for their medicinal value and health benefits, particularly the species Agaricus bisporus , which is rich in bioactive components. However,…”
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The importance of CD39, CD43, CD81, and CD95 expression for differentiating B cell lymphoma by flow cytometry
Published in Cytometry. Part B, Clinical cytometry (01-05-2018)“…Background B cell lymphomas' (BCL) current diagnosis is usually based on a combination of morphology, immunophenotype, recurrent cytogenetic aberration and…”
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Profile of blood donations with a positive serology in Southern Brazil
Published in Hematology, Transfusion and Cell Therapy (01-04-2020)“…The aim of this study was to describe the characteristics of blood donors and the serological profile of the blood donations at the blood bank of the…”
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Follow-up and outcome of the twelve-year experience in adult patients with acute promyelocytic leukemia
Published in Hematology, Transfusion and Cell Therapy (01-01-2021)“…Acute promyelocytic leukemia is a subtype of acute myeloid leukemia, characterized by the presence of neoplastic promyelocytes, due to the reciprocal balanced…”
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10
Apoptotic Events Induced by Maleimides on Human Acute Leukemia Cell Lines
Published in Chemical research in toxicology (16-12-2013)“…Cyclic imides are known for their antitumor activity, especially the naphthalimide derivatives, such as Mitonafide and Amonafide. Recently, we have…”
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11
Impact of Serum Amyloid A Protein in the Human Breast: An In Vitro Study
Published in Nutrients (16-07-2024)“…The mammary gland is an exocrine gland whose main function is to produce milk. Breast morphogenesis begins in the embryonic period; however, its greatest…”
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12
Prevalence of Factor V Leiden in a healthy population in Santa Catarina, Southern Brazil
Published in International journal of laboratory hematology (01-04-2021)“…Thrombophilic disorders are found in 50% of patients with venous thromboembolism, and factor V Leiden (FVL) is the most common genetic risk factor for the…”
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13
Synthesis of chalcones derived from 1-naphthylacetophenone and evaluation of their cytotoxic and apoptotic effects in acute leukemia cell lines
Published in Bioorganic chemistry (01-11-2021)“…[Display omitted] •The chalcones F07, F09 and F10 were strongly cytotoxic to AML (K562) and ALL (Jurkat) cell lines.•F07, F09 and F10 were not cytotoxic to…”
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14
Complement component 3 (C3) as a biomarker for insulin resistance after bariatric surgery
Published in Clinical biochemistry (01-06-2017)“…Since complement system has been recently associated with metabolic and cardiovascular diseases, and closely related to insulin resistance, we investigated the…”
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Drug binding and drug-drug interaction considerations in individuals with obesity before and after bariatric surgery: A retrospective cross-sectional study
Published in Medicine in drug discovery (01-06-2023)“…•Protein binding is altered after bariatric surgery and impacts the pharmacodynamics of certain drugs.•Serum AAG showed a significant reduction after 12 months…”
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16
Determination of normal expression patterns of CD86, CD210a, CD261, CD262, CD264, CD358, and CD361 in peripheral blood and bone marrow cells by flow cytometry
Published in Immunology letters (01-02-2018)“…•Markers are not expressed in a single lineage but in several leukocyte cells.•CD210a and CD261 expression differ for data presented in other studies.•CD210a…”
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Determination of lymphocyte subset reference ranges in peripheral blood of healthy adults by a dual-platform flow cytometry method
Published in Immunology letters (01-01-2015)“…Highlights 1. T CD3+, T CD4+, T CD8+, T CD4+CD8+ cells presented higher values in females. 2. CD19+CD20− cells presented higher values in females. 3. Mature,…”
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Effects of 1,3,5-triphenyl-4,5-dihydro-1H-pyrazole derivatives on cell-cycle and apoptosis in human acute leukemia cell lines
Published in Canadian journal of physiology and pharmacology (01-05-2017)“…Pyrazoline is an important 5-membered nitrogen heterocycle that has been extensively researched. Ten derivatives were synthesized and tested for antileukemic…”
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Investigation of cellular mechanisms involved in apoptosis induced by a synthetic naphthylchalcone in acute leukemia cell lines
Published in Anti-cancer drugs (01-09-2016)“…We have previously reported the cytotoxic effects of chalcone A1, derived from 1-naphthaldehyde, in leukemia cell lines. On the basis of these findings, the…”
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Importance of Detecting Multidrug Resistance Proteins in Acute Leukemia Prognosis and Therapy
Published in Journal of clinical laboratory analysis (01-01-2013)“…Multidrug resistance (MDR) is a multifactorial phenomenon and the role of these proteins in generating the MDR phenotype is controversial. With this in mind,…”
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