Search Results - "De Miranda, Aline Silva"
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Brain-derived neurotrophic factor is down regulated after bovine alpha-herpesvirus 5 infection in both wild-type and TLR3/7/9 deficient mice
Published in Journal of Veterinary Medical Science (2021)“…Neurotrophic factors have been implicated in the control of neuronal survival and plasticity in different brain diseases. Meningoencephalitis caused by bovine…”
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Clinical and molecular correlates of the ASPECTS in the acute phase of stroke
Published in Arquivos de neuro-psiquiatria (01-05-2020)“…ABSTRACT Background: The Alberta Stroke Program Early CT Score (ASPECTS) scale was developed for monitoring early ischemic changes on CT, being associated with…”
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Inhibition of CSF1R, a receptor involved in microglia viability, alters behavioral and molecular changes induced by cocaine
Published in Scientific reports (06-08-2021)“…Different data suggest that microglia may participate in the drug addiction process as these cells respond to neurochemical changes induced by the…”
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siRNA lipid nanoparticles for CXCL12 silencing modulate brain immune response during Zika infection
Published in Biomedicine & pharmacotherapy (01-01-2024)“…CXCL12 is a key chemokine implicated in neuroinflammation, particularly during Zika virus (ZIKV) infection. Specifically, CXCL12 is upregulated in circulating…”
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Renin-Angiotensin-Aldosterone System and Migraine: A Systematic Review of Human Studies
Published in Protein and peptide letters (01-01-2020)“…Migraine is a common neurologic condition marked by recurrent episodes of headache. Its pathophysiology is highly complex involving neuronal, inflammatory and…”
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TNFR1 plays a critical role in the control of severe HSV-1 encephalitis
Published in Neuroscience letters (19-07-2010)“…Herpes simplex virus-1 (HSV-1) is a pathogen for humans that may cause severe encephalitis. Tumor necrosis factor α (TNF-α) plays a role in several viral…”
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Traumatic brain injury in Brazil: an epidemiological study and systematic review of the literature
Published in Arquivos de neuro-psiquiatria (01-04-2022)“…ABSTRACT Background: Traumatic brain injury (TBI) is a serious public health problem worldwide. Although TBI is common in developing countries, there are few…”
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Circulating levels of sTNFR1 as a marker of severe clinical course in schizophrenia
Published in Journal of psychiatric research (01-04-2013)“…Abstract Background Schizophrenia (SZ) has been associated with an imbalance in the inflammatory cytokine TNF-α. The objectives of this study were to compare…”
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Clinical correlates of social cognition after an ischemic stroke: preliminary findings
Published in Dementia & neuropsychologia (01-04-2021)“…The co-occurrence of post-stroke behavioral disorders and cognitive impairment has been extensively investigated. However, studies usually do not include…”
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Association Between Inflammatory Biomarkers in Plasma, Radiological Severity, and Duration of Exposure in Patients With Silicosis
Published in Journal of occupational and environmental medicine (01-05-2014)“…OBJECTIVE:To evaluate the plasma levels of CCL2, CCL3, CCL11, CCL24, tumor necrosis factor alpha, sTNFR1, and sTNFR2 in subjects exposed to silica (SES) with…”
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Increased BDNF Levels in Long-term Bipolar Disorder Patients
Published in Revista brasileira de psiquiatria (01-03-2013)“…Bipolar disorder (BD) is a prevalent, chronic and progressive illness. There is a growing body of evidence indicating that brain-derived neurotrophic factor…”
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Insights into Neuroinflammation in Parkinson’s Disease: From Biomarkers to Anti-Inflammatory Based Therapies
Published in BioMed research international (01-01-2015)“…Parkinson’s disease (PD) is the second most common neurodegenerative disorder worldwide, being characterized by the progressive loss of dopaminergic neurons in…”
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Association between executive and food functions in the acute phase after stroke
Published in Arquivos de neuro-psiquiatria (01-03-2018)“…ABSTRACT Purpose To investigate potential associations among executive, physical and food functions in the acute phase after stroke. Methods This is a…”
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Role of the suppressor of cytokine signaling 2 (SOCS2) during meningoencephalitis caused by Bovine herpesvirus 5 (BoHV-5)
Published in Comparative immunology, microbiology and infectious diseases (01-08-2016)“…Highlights • SOCS2 plays a role in the pathogenesis of experimental BoHV-5 meningoencephalitis. • SOCS2 deficient mice infected with BoHV-5 exhibited…”
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Targeting the Renin-Angiotensin System (RAS) for Neuropsychiatric Disorders
Published in Current neuropharmacology (01-01-2024)“…Background: Neuropsychiatric disorders, such as mood disorders, schizophrenia, and Alzheimer’s disease (AD) and related dementias, are associated to…”
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Behavioral investigation of mice with experimental autoimmune encephalomyelitis
Published in Arquivos de neuro-psiquiatria (01-12-2011)“…Multiple sclerosis is a neuroinflammatory disease that results in serious neurological disability. Besides physical impairment, behavioral symptoms are also…”
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Absence of TNFR1 promotes a protective response in the early phase of hepatic encephalopathy induced by thioacetamide in mice
Published in Neuroscience letters (01-11-2024)“…Hepatic encephalopathy (HE) is a neuropsychiatric syndrome with a wide spectrum of cognitive deficits, motor impairment, and psychiatric disturbances resulting…”
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Oxidative Stress in Microbial Diseases: Pathogen, Host, and Therapeutics
Published in Oxidative medicine and cellular longevity (01-01-2019)“…[...]the modulation of the host’s redox system as an antimicrobial therapeutic strategy is challenging. The redox metabolism in microorganisms is based on a…”
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Innate and adaptive immune gene expression in the brain is associated with neuropathological changes after infection with bovine alpha-herpesvirus-5 in mice
Published in Veterinary microbiology (01-10-2023)“…Bovine alpha herpesvirus-5 (BoAHV-5) is related to the development of meningoencephalitis in cattle. Very little is known about the molecular pathways involved…”
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The behavior and diagnostic utility of procalcitonin and five other inflammatory molecules in critically ill patients with respiratory distress and suspected 2009 influenza a H1N1 infection
Published in Clinics (São Paulo, Brazil) (01-01-2012)“…During the 2009 influenza A H1N1 pandemic, it became difficult to differentiate viral infections from other conditions in patients admitted to the intensive…”
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