Search Results - "De Meyer, G R"

Reactive oxygen species induce RNA damage in human atherosclerosis by Martinet, W., De Meyer, G. R. Y., Herman, A. G., Kockx, M. M.

“…Background  Reactive oxygen species (ROS)‐induced DNA damage has recently been identified in both human and experimental atherosclerosis. This study was…”
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[18F]ZCDD083: A PFKFB3-Targeted PET Tracer for Atherosclerotic Plaque Imaging by De Dominicis, Carlo, Perrotta, Paola, Dall’Angelo, Sergio, Wyffels, Leonie, Staelens, Steven, De Meyer, G. R. Y, Zanda, Matteo

“…PFKFB3, a glycolysis-related enzyme upregulated in inflammatory conditions and angiogenesis, is an emerging target for diagnosis and therapy of…”
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RNA synthesis and splicing interferes with DNA in situ end labeling techniques used to detect apoptosis by Kockx, MM, Muhring, J, Knaapen, MW, de Meyer, GR

“…The detection of DNA fragmentation by the use of the TUNEL technique has become a standard technique for the detection of apoptosis in tissue sections. DNA…”
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Biotin- or digoxigenin-conjugated nucleotides bind to matrix vesicles in atherosclerotic plaques by Kockx, MM, Muhring, J, Bortier, H, De Meyer, GR, Jacob, W

“…The present study analyzes the staining pattern of DNA in situ end-labeling techniques of human and rabbit atherosclerotic plaques. Both the terminal…”
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Nitric oxide selectively depletes macrophages in atherosclerotic plaques via induction of endoplasmic reticulum stress by Martinet, W, Croons, V, Timmermans, J‐P, Herman, A G, Meyer, G R Y

“…Background and purpose: Macrophages in atherosclerotic plaques have a tremendous impact on atherogenesis and plaque destabilization. We previously demonstrated…”
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Triphasic sequence of neointimal formation in the cuffed carotid artery of the rabbit by KOCKX, M. M, DE MEYER, G. R. Y, JACOB, W. A, BULT, H, HERMAN, A. G

“…A nonocclusive silicone cuff placed around the rabbit carotid artery results in a diffuse intimal thickening. The early stages of this phenomenon were studied…”
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Reproducible determination of transpulmonary pressures by De Meyer, G.R.A., Morrison, S.G., Saldien, V., Jorens, P.G., Schepens, T.

“…Oesophageal pressures, as measured in an oesophageal balloon catheter, are a validated substitute for pleural pressures. Transpulmonary pressures,…”
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Fibrillin-1 impairment enhances blood–brain barrier permeability and xanthoma formation in brains of apolipoprotein E-deficient mice by Van der Donckt, C, Roth, L, Vanhoutte, G, Blockx, I, Bink, D.I, Ritz, K, Pintelon, I, Timmermans, J.-P, Bauters, D, Martinet, W, Daemen, M.J, Verhoye, M, De Meyer, G.R.Y

“…Highlights • Dysfunctional fibrillin-1 impairs blood–brain barrier integrity. • Peripheral leukocyte infiltration further degrades the blood–brain barrier. •…”
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Fibrin(ogen) and von Willebrand Factor Deposition Are Associated With Intimal Thickening After Balloon Angioplasty of the Rabbit Carotid Artery by Bosmans, J.M, Kockx, M.M, Vrints, C.J, Bult, H, De Meyer, G.R.Y, Herman, A.G

“…The aim of the study was to assess the contribution of thrombus incorporation into neointimal thickening in the rabbit carotid artery after deep vascular…”
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POTENTIAL IMPACT OF POLICY REGULATION AND GENERIC COMPETITION ON SALES OF CHOLESTEROL LOWERING MEDICATION, ANTIDEPRESSANTS AND ACID BLOCKING AGENTS IN BELGIUM by Fraeyman, J, Van Hal, G, De Loof, H, Remmen, R, De Meyer, GRY, Beutels, P

“…Background: Pharmaceutical expenditures are increasing as a proportion of health expenditures in most rich countries. Antidepressants, acid blocking agents and…”
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Longitudinal follow-up of ascending versus abdominal aortic aneurysm formation in angiotensin II-infused ApoE−/− mice by Trachet, Bram, Renard, M, Van der Donckt, C, Deleye, S, Bols, J, De Meyer, G.R.Y, Staelens, S, Loeys, B.L, Segers, P

“…Abstract Purpose To explore new imaging techniques to elucidate some of the differences between both abdominal and ascending aortic aneurysms in the…”
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Apoptosis and related proteins in different stages of human atherosclerotic plaques by KOCKX, M. M, DE MEYER, G. R. Y, MUHRING, J, JACOB, W, BULT, H, HERMAN, A. G

“…The transition of a fatty streak into an atherosclerotic plaque is characterized by the appearance of focal and diffuse regions of cell death. We have…”
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The endothelium during cuff-induced neointima formation in the rabbit carotid artery by KOCKX, M. M, DE MEYER, G. R. Y, ANDRIES, L. J, BULT, H, JACOB, W. A, HERMAN, A. G

“…Intimal thickening in human arteries is considered as a site of predilection for atherosclerosis. The placement of a flexible, physically nonconstrictive,…”
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P2.02: In Vivo Visualisation and Reconstruction of the Mouse Cerebral Vasculature Using Contrast Enhanced Micro-Ct by De Wilde, D., Trachet, B., Van der Donckt, C., Vandeghinste, B., Descamps, B., Van Holen, R., Vanhove, C., De Meyer, G. R. Y., Segers, P.

“…Introduction Recently, a mouse model was developed showing spontaneous plaque rupture leading to stroke (ApoE −/− Fbn1 C1039G+/− mouse). However, a…”
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Vasoconstrictor responses after neo‐intima formation and endothelial removal in the rabbit carotid artery by Meyer, Guido R.Y., Bult, Hidde, Üstünes, Levent, Kockx, Mark, Jordaens, François H., Zonnekeyn, Ludo L., Herman, Arnold G.

“…1 The present study examined the responses of the rabbit carotid artery to five vasoconstrictors after neo‐intima formation induced by perivascular collar…”
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ERBB4 stimulation mitigates atrial fibrillation and remodeling in a porcine DOCA model by Tubeeckx, M R L, Goovaerts, B, Van Fraeyenhove, J, Murphy, S L, De Meyer, G R Y, De Keulenaer, G W, Heidbuchel, H, Segers, V F M

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Cell Composition, Replication, and Apoptosis in Atherosclerotic Plaques After 6 Months of Cholesterol Withdrawal by Kockx, Mark M, De Meyer, Guido R.Y, Buyssens, Norbert, Knaapen, Michiel W.M, Bult, Hidde, Herman, Arnold G

“…Unstable human atherosclerotic plaques are characterized by a thin fibrous cap that contains few smooth muscle cells (SMCs) and numerous foam cells of…”
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The role of endothelial cells in the relaxations induced by 13‐hydroxy‐ and 13‐hydroperoxylinoleic acid in canine arteries by Meyer, Guido R.Y., Bult, Hidde, Verbeuren, Tony J., Herman, Arnold G.

“…1 One of the major fatty acids in the arterial wall is linoleic acid. It has been shown that its 13‐hydroxy metabolite (13‐HODE) is generated in significant…”
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Neointima Formation Impairs Endothelial Muscarinic Receptors While Enhancing Prostacyclin-Mediated Responses in the Rabbit Carotid Artery by De Meyer, Guido R.Y, Bult, Hidde, Hoydonck, Anne-Elise Van, Jordaens, François H, Buyssens, Norbert, Herman, Arnold G

“…The purpose of this study was to determine whether the generation of a neointima, an early step in the development of atherosclerosis, affects…”
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P4995Neuregulin-1 compensates for endothelial NO synthase deficiency in the heart and kidney by Shakeri, H, De Moudt, S, Leloup, A J, Jacobs, G, De Meyer, G R Y, De Keulenaer, G W, Fransen, P, Guns, P.-J.F, Segers, V F

“…Abstract Background Decreased eNOS activity is the hallmark of endothelial dysfunction and is associated with cardiovascular and renal disorders. Besides NO,…”
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