Search Results - "De Mey, Sven"

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  1. 1

    Immunomodulation of the Tumor Microenvironment: Turn Foe Into Friend by Locy, Hanne, de Mey, Sven, de Mey, Wout, De Ridder, Mark, Thielemans, Kris, Maenhout, Sarah K

    Published in Frontiers in immunology (11-12-2018)
    “…Immunotherapy, where the patient's own immune system is exploited to eliminate tumor cells, has become one of the most prominent new cancer treatment options…”
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    Journal Article
  2. 2

    Radioresistance of Human Cancers: Clinical Implications of Genetic Expression Signatures by de Mey, Sven, Dufait, Inès, De Ridder, Mark

    Published in Frontiers in oncology (27-10-2021)
    “…Although radiotherapy is given to more than 50% of cancer patients, little progress has been made in identifying optimal radiotherapy - drug combinations to…”
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    Journal Article
  3. 3

    Dichloroacetate Radiosensitizes Hypoxic Breast Cancer Cells by de Mey, Sven, Dufait, Inès, Jiang, Heng, Corbet, Cyril, Wang, Hui, Van De Gucht, Melissa, Kerkhove, Lisa, Law, Ka Lun, Vandenplas, Hugo, Gevaert, Thierry, Feron, Olivier, De Ridder, Mark

    “…Mitochondrial metabolism is an attractive target for cancer therapy. Reprogramming metabolic pathways can potentially sensitize tumors with limited treatment…”
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  4. 4

    Antidiabetic Biguanides Radiosensitize Hypoxic Colorectal Cancer Cells Through a Decrease in Oxygen Consumption by de Mey, Sven, Jiang, Heng, Corbet, Cyril, Wang, Hui, Dufait, Inès, Law, Kalun, Bastien, Estelle, Verovski, Valeri, Gevaert, Thierry, Feron, Olivier, De Ridder, Mark

    Published in Frontiers in pharmacology (03-10-2018)
    “…The anti-diabetic biguanide drugs metformin and phenformin exhibit antitumor activity in various models. However, their radiomodulatory effect under hypoxic…”
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    Piperlongumine increases sensitivity of colorectal cancer cells to radiation: Involvement of ROS production via dual inhibition of glutathione and thioredoxin systems by Wang, Hui, Jiang, Heng, Corbet, Cyril, de Mey, Sven, Law, Kalun, Gevaert, Thierry, Feron, Olivier, De Ridder, Mark

    Published in Cancer letters (28-05-2019)
    “…Piperlongumine (PL), naturally synthesized in long pepper, is known to selectively kill tumor cells via perturbation of reactive oxygen species (ROS)…”
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    Auranofin radiosensitizes tumor cells through targeting thioredoxin reductase and resulting overproduction of reactive oxygen species by Wang, Hui, Bouzakoura, Soumaya, de Mey, Sven, Jiang, Heng, Law, Kalun, Dufait, Inès, Corbet, Cyril, Verovski, Valeri, Gevaert, Thierry, Feron, Olivier, Van den Berge, Dirk, Storme, Guy, De Ridder, Mark

    Published in Oncotarget (30-05-2017)
    “…Auranofin (AF) is an anti-arthritic drug considered for combined chemotherapy due to its ability to impair the redox homeostasis in tumor cells. In this study,…”
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    Journal Article
  9. 9

    Inhibition of Phosphoglycerate Dehydrogenase Radiosensitizes Human Colorectal Cancer Cells under Hypoxic Conditions by Van de Gucht, Melissa, Dufait, Inès, Kerkhove, Lisa, Corbet, Cyril, de Mey, Sven, Jiang, Heng, Law, Ka Lun, Gevaert, Thierry, Feron, Olivier, De Ridder, Mark

    Published in Cancers (15-10-2022)
    “…Augmented de novo serine synthesis activity is increasingly apparent in distinct types of cancers and has mainly sparked interest by investigation of…”
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  10. 10

    Potential of memory T cells in bridging preoperative chemoradiation and immunotherapy in rectal cancer by de Mey, Sven, Jiang, Heng, Wang, Hui, Engels, Benedikt, Gevaert, Thierry, Dufait, Inès, Feron, Olivier, Aerts, Joeri, Verovski, Valeri, De Ridder, Mark

    Published in Radiotherapy and oncology (01-06-2018)
    “…The management of locally advanced rectal cancer has passed a long way of developments, where total mesorectal excision and preoperative radiotherapy are…”
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