Search Results - "De Mey, J G. R"
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Two-photon microscopy of vital murine elastic and muscular arteries. Combined structural and functional imaging with subcellular resolution
Published in Journal of vascular research (01-02-2007)“…Understanding vascular pathologies requires insight in the structure and function, and, hence, an imaging technique combining subcellular resolution, large…”
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Agonist‐dependent modulation of arterial endothelinA receptor function
Published in British journal of pharmacology (01-07-2012)“…BACKGROUND AND PURPOSE Endothelin‐1 (ET‐1) causes long‐lasting vasoconstrictions. These can be prevented by ETA receptor antagonists but are only poorly…”
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Chronic hypoxia stimulates periarterial sympathetic nerve development in chicken embryo
Published in Circulation (New York, N.Y.) (05-12-2000)“…Epidemiological findings suggest an association between low-for-age birth weight and the risk to develop coronary heart diseases in adulthood. During…”
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Myoendothelial coupling in the mesenteric arterial bed; segmental differences and interplay between nitric oxide and endothelin‐1
Published in British journal of pharmacology (01-04-2009)“…Background and purpose: We tested the hypothesis that activated arterial smooth muscle (ASM) stimulates endothelial vasomotor influences via gap junctions and…”
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Altered Flow–Induced Arterial Remodeling in Vimentin-Deficient Mice
Published in Arteriosclerosis, thrombosis, and vascular biology (01-03-2000)“…ABSTRACTThe endothelial cytoskeleton plays a key role in arterial responses to acute changes in shear stress. We evaluated whether the intermediate filament…”
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Role of newly formed platelets in thrombus formation in rat after clopidogrel treatment: comparison to the reversible binding P2Y₁₂ antagonist ticagrelor
Published in Thrombosis and haemostasis (01-12-2011)“…Platelet P2Y₁₂ receptors play an important role in arterial thrombosis by stimulating thrombus growth. Both irreversibly (clopidogrel) and reversibly binding…”
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Sympathetic control of the cardiovascular response to acute hypoxemia in the chick embryo
Published in American journal of physiology. Regulatory, integrative and comparative physiology (01-04-2002)“…In response to an acute hypoxemic insult, the mammalian fetus shows a redistribution of the cardiac output in favor of the heart and brain. Peripheral…”
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Direct effects of acute hypoxia on the reactivity of peripheral arteries of the chicken embryo
Published in American journal of physiology. Regulatory, integrative and comparative physiology (01-08-2002)“…In the chicken embryo, acute hypoxemia results in cardiovascular responses, including an increased peripheral resistance. We investigated whether local direct…”
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Endothelium‐dependent hyperpolarizations in health and disease
Published in Acta Physiologica (01-01-2017)Get full text
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Endothelin‐1 and endothelin‐2 initiate and maintain contractile responses by different mechanisms in rat mesenteric and cerebral arteries
Published in British journal of pharmacology (01-11-2013)“…Background and Purpose Endothelin (ET)‐1 and ET‐2 cause potent long‐lasting vasoconstrictions by tight binding to smooth muscle ETA receptors. We tested the…”
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Mechanisms leading to increased vasodilator responses to calcitonin-gene-related peptide in mesenteric resistance arteries of early pregnant rats
Published in Journal of vascular research (01-01-2008)“…The objective of this study was to explore the mechanism responsible for the higher relaxing responses of mesenteric arteries to calcitonin-gene-related…”
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Selective endothelin B receptor blockade does not influence BNP-induced natriuresis in man
Published in Kidney international (01-03-2006)“…Brain natriuretic peptide (BNP) and endothelin-1 (ET-1) both exhibit natriuretic activity within the human kidney. Furthermore, they both act partly through…”
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Pharmacokinetic and pharmacodynamic properties of SOL1: A novel dual inhibitor of neutral endopeptidase and endothelin converting enzyme
Published in Life sciences (1973) (15-10-2012)“…The pharmacological profile of the novel putative neutral endopeptidase (NEP) and endothelin converting enzyme (ECE) inhibitor SOL1 was examined. The enzyme…”
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Pregnancy enhances the prejunctional vasodilator response to adrenomedullin in selective regions of the arterial bed of Wistar rats
Published in Reproductive sciences (Thousand Oaks, Calif.) (01-12-2007)“…The objective of this study is to determine whether the vascular response to adrenomedullin is modulated by pregnancy. To this end, the authors study the…”
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Effects of prenatal hypoxia on pulmonary vascular reactivity in chickens prone to pulmonary hypertension
Published in Journal of physiology and pharmacology : an official journal of the Polish Physiological Society (01-03-2009)“…Among chickens, meat-producing broiler strains are highly prone to develop severe pulmonary hypertension (PH) that is accompanied by endothelial dysfunction in…”
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Developmental changes in endothelium-dependent relaxation of the chicken ductus arteriosus
Published in Journal of physiology and pharmacology : an official journal of the Polish Physiological Society (01-03-2008)“…We tested the hypothesis that endothelium-dependent relaxation in the chicken ductus arteriosus (DA) is developmentally regulated. Isolated DA rings from 15-,…”
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Tissue-specific utilization of menaquinone-4 results in the prevention of arterial calcification in warfarin-treated rats
Published in Journal of vascular research (01-11-2003)“…The effects of vitamin K (phylloquinone: K1 and menaquinone-4: MK-4) on vascular calcification and their utilization in the arterial vessel wall were compared…”
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The pharmacology of calcium antagonists: a review
Published in Journal of cardiovascular pharmacology (1990)“…Calcium antagonists are a group of drugs with widely varying pharmacological properties and a broad range of therapeutic applications. At least four major…”
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Development of vasomotor responses in fetal mesenteric arteries
Published in American journal of physiology. Heart and circulatory physiology (01-09-2000)“…Changes in mesenteric arterial diameters were studied using intravital microscopy in chick fetuses at days 13 and 17 of incubation, corresponding to 0.6 and…”
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