Search Results - "De May, Henning"
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High-fat diet consumption disrupts memory and primes elevations in hippocampal IL-1β, an effect that can be prevented with dietary reversal or IL-1 receptor antagonism
Published in Brain, behavior, and immunity (01-11-2014)“…Abstract High-fat diet (HFD)-induced obesity is reaching worldwide proportions. In addition to causing obesity, HFDs also induce a variety of health disorders,…”
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Cancer vaccines from cryogenically silicified tumour cells functionalized with pathogen-associated molecular patterns
Published in Nature biomedical engineering (01-01-2022)“…The production of personalized cancer vaccines made from autologous tumour cells could benefit from mechanisms that enhance immunogenicity. Here we show that…”
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Regional immune mechanisms enhance efficacy of an autologous cellular cancer vaccine with intraperitoneal administration
Published in Oncoimmunology (31-12-2024)“…Widespread peritoneal dissemination is common in patients with gynecologic or gastrointestinal cancers. Accumulating evidence of a central role for regional…”
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Monitoring Therapeutic Responses to Silicified Cancer Cell Immunotherapy Using PET/MRI in a Mouse Model of Disseminated Ovarian Cancer
Published in International journal of molecular sciences (10-09-2022)“…Current imaging approaches used to monitor tumor progression can lack the ability to distinguish true progression from pseudoprogression. Simultaneous…”
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Beyond Men, Women, or Both: A Comprehensive, LGBTQ-Inclusive, Implicit-Bias-Aware, Standardized-Patient-Based Sexual History Taking Curriculum
Published in MedEdPORTAL (28-09-2017)“…This standardized-patient-based module prepares medical students to take inclusive, comprehensive sexual histories from patients of all sexual orientations and…”
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Abstract B01: Optimizing chemotherapy for the integration of immune therapy in ovarian cancer: Enriching effector T cells in the peritoneal tumor microenvironment using the route of cisplatin administration (IV vs. IP)
Published in Clinical cancer research (01-07-2020)“…Abstract Background/Objective: Despite its success in treating other tumor types, immune therapy has underperformed in ovarian cancer. One reason may be the…”
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The Association Between Interview Day and Rank Order in Plastic Surgery Match: Is Recency Effect to Blame?
Published in Journal of surgical education (01-08-2023)“…•Integrated plastic surgery applicants who interviewed on day 1 were had worse rank scores.•Integrated applicants who interviewed during their subinternship…”
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CD49d (high) T cells in the ovarian cancer microenvironment are a potential target for the optimization of immune checkpoint therapy in ovarian cancer
Published in Journal of clinical oncology (20-05-2019)“…Abstract only e17075 Background: Despite the correlation between tumor infiltrating lymphocytes and long-term survival, immune-based therapies have…”
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Botulinum Toxin A for the Treatment of Sympathomimetic Pressor-Induced Digital Hand Ischemia in the Critically Ill Intensive Care Unit Patient
Published in Hand (New York, N.Y.) (01-09-2022)“…Vasopressor-induced ischemia of the hand, while relatively rare, is a severe complication in critically ill intensive care unit (ICU) patients requiring high…”
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Immune Modulation of the Peritoneal Ovarian Tumor Microenvironment Using Both Novel and Standard of Care Therapies
Published 01-01-2022“…Tumor immunotherapy has revolutionized the treatment paradigm of several malignancies, including lung cancer and melanoma. Despite significant evidence that…”
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TLR Agonist Nano Immune Therapy Clears Peritoneal and Systemic Ovarian Cancer
Published in Advanced healthcare materials (31-10-2024)“…Intraperitoneal (IP) administration of immunogenic mesoporous silica nanoparticles (iMSN) in a mouse model of metastatic ovarian cancer promotes the…”
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