Search Results - "De Luca, Heidi E"
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Intoxication of zebrafish and mammalian cells by cholera toxin depends on the flotillin/reggie proteins but not Derlin-1 or -2
Published in The Journal of clinical investigation (01-12-2010)“…Cholera toxin (CT) causes the massive secretory diarrhea associated with epidemic cholera. To induce disease, CT enters the cytosol of host cells by co-opting…”
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Journal Article -
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Role of p97 AAA-ATPase in the Retrotranslocation of the Cholera Toxin A1 Chain, a Non-ubiquitinated Substrate
Published in The Journal of biological chemistry (29-07-2005)“…The enzymatic A1 chain of cholera toxin retrotranslocates across the endoplasmic reticulum membrane into the cytosol, where it induces toxicity. Almost all…”
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A biochemical method for tracking cholera toxin transport from plasma membrane to Golgi and endoplasmic reticulum
Published in Methods in molecular biology (Clifton, N.J.) (2006)“…Asiatic cholera is a rapidly progressing disease resulting in extreme diarrhea and even death. The causative agent, cholera toxin, is an AB5-subunit…”
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Journal Article