Search Results - "De Lima, Thereza Christina Monteiro"
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Role of NPY Y1 receptor on acquisition, consolidation and extinction on contextual fear conditioning: Dissociation between anxiety, locomotion and non-emotional memory behavior
Published in Neurobiology of learning and memory (01-07-2013)“…•Low dose of NPY reduced fear responses in rats.•The blockade of Y1 receptor prevented the effects of NPY on conditioned fear.•Y1-agonist Leu31Pro34-NPY…”
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Distinctive stress sensitivity and anxiety-like behavior in female mice: Strain differences matter
Published in Neurobiology of stress (01-11-2018)“…Epidemiologic studies have shown that the prevalence of stress-related mood disorders is higher in women, which suggests a different response of neuroendocrine…”
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Psychopharmacological effects and safety of styryl‐2‐pyrones and dihydrostyryl‐2‐pyrones‐rich fraction from Polygala sabulosa: absence of withdrawal syndrome and tolerance to anxiolytic‐like and anticonvulsant effects
Published in Journal of pharmacy and pharmacology (01-09-2018)“…Objectives To investigate whether mice develop tolerance to the anxiolytic‐like and anticonvulsant effects of subchronic treatment with EA (the…”
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Neuropharmacological activity of the pericarp of Passiflora edulis flavicarpa degener: putative involvement of C-glycosylflavonoids
Published in Experimental biology and medicine (Maywood, N.J.) (01-08-2009)“…Passiflora edulis has been used in traditional medicine as a sedative and to treat or prevent central disorders such as anxiety and insomnia. In this study,…”
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Short- and long-term anxiogenic effects induced by a single injection of subconvulsant doses of pilocarpine in rats: investigation of the putative role of hippocampal pathways
Published in Psychopharmacologia (01-12-2010)“…Rationale Behavioral consequences of convulsive episodes are well documented, but less attention was paid to changes that occur in response to subconvulsant…”
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Restraint stress potentiates neuropeptide Y-mediated impairment on spatial memory in rats
Published in Behavioural brain research (15-02-2022)“…Memory is the ability to store, retrieve and use information that requires a progressive time-dependent stabilization process known as consolidation to be…”
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Anticonvulsant and anxiolytic-like effects of compounds isolated from Polygala sabulosa (Polygalaceae) in rodents: in vitro and in vivo interactions with benzodiazepine binding sites
Published in Psychopharmacologia (01-04-2008)“…Rationale Polygala sabulosa , a folk medicine, presents dihydrostyryl-2-pyrones (DST) and styryl-2-pyrones (STY), compounds structurally similar to…”
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The anxiolytic-like effect of an essential oil derived from Spiranthera odoratissima A. St. Hil. leaves and its major component, β-caryophyllene, in male mice
Published in Progress in neuro-psychopharmacology & biological psychiatry (07-08-2012)“…Spiranthera odoratissima A. St. Hil. (manacá) is used in folk medicine to treat renal and hepatic diseases, stomachache, headaches and rheumatism. A central…”
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The sedative activity of flavonoids from Passiflora quadrangularis is mediated through the GABAergic pathway
Published in Biomedicine & pharmacotherapy (01-04-2018)“…[Display omitted] The aim of this study was to investigate the sedative activity of the aqueous leaf extract of Passiflora quadrangularis, a species that is…”
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A proposal for refining the forced swim test in Swiss mice
Published in Progress in neuro-psychopharmacology & biological psychiatry (01-08-2013)“…The forced swim test (FST) is a preclinical test to the screening of antidepressants based on rats or mice behaviours, which is also sensitive to stimulants of…”
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The microinjection of AMPA receptor antagonist into the accumbens shell, but not into the accumbens core, induces anxiolysis in an animal model of anxiety
Published in Behavioural brain research (17-03-2008)“…This study investigated the effect of the AMPA receptor antagonist 6,7-dinitroquinoxaline-2,3-dione (DNQX) microinjected into the core and shell sub-regions of…”
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Enduring effects of muscarinic receptor activation on adult hippocampal neurogenesis, microRNA expression and behaviour
Published in Behavioural brain research (19-04-2019)“…[Display omitted] •mAChR activation promotes AHN and ectopic migration.•Single pilocarpine exposure alters anxiety-like and depression-like…”
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Involvement of the monoamine system in antidepressant-like properties of 4-(1-phenyl-1h-pyrazol-4-ylmethyl)-piperazine-1-carboxylic acid ethyl ester
Published in Life sciences (1973) (15-12-2015)“…Piperazinic derivatives have therapeutic potential by acting as analgesic, antidepressant-like, anticonvulsant and antipsychotic in preclinical studies. In…”
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Short-term enriched environment exposure facilitates fear extinction in adult rats: The NPY-Y1 receptor modulation
Published in Neuropeptides (Edinburgh) (01-02-2016)“…Abstract Neuropeptides have an important role in several psychiatric conditions. Among them, neuropeptide Y (NPY) seems to be essential to modulate some…”
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Central pharmacological activity of a new piperazine derivative: 4-(1-Phenyl-1h-pyrazol-4-ylmethyl)-piperazine-1-carboxylic acid ethyl ester
Published in Life sciences (1973) (14-06-2012)“…Our study focuses on the design and synthesis of a new piperazinic derivate, 4-(1-phenyl-1h-Pyrazol-4-Ylmethyl)-Piperazine-1-Carboxylic Acid Ethyl ester…”
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NK1 receptors antagonism of dorsal hippocampus counteract the anxiogenic-like effects induced by pilocarpine in non-convulsive Wistar rats
Published in Behavioural brain research (15-05-2014)“…•NK1 receptor antagonist's FK888 did not alter emotional responses in CA1 or LSD.•Infusion of FK888 into CA1 inhibits long-term anxiogenic responses induced by…”
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Effects of social isolation and enriched environment on behavior of adult Swiss mice do not require hippocampal neurogenesis
Published in Behavioural brain research (20-11-2011)“…► Enriched and impoverished rearing reduced risk assessment in elevated plus-maze. ► Isolation rearing induced hyperactivity in open field test. ► Enrichment…”
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GABA-A receptor modulators alter emotionality and hippocampal theta rhythm in an animal model of long-lasting anxiety
Published in Brain research (26-09-2013)“…Abstract The cholinergic system is implicated in emotional regulation. The injection of non-convulsant doses of the muscarinic receptor agonist pilocarpine…”
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Involvement of GABAergic non-benzodiazepine sites in the anxiolytic-like and sedative effects of the flavonoid baicalein in mice
Published in Behavioural brain research (01-08-2011)“…► Baicalein showed anxiolytic and sedative effects by the i.c.v. route. ► Baicalein's central effects were blocked by pentyleneterazol and DHEAS, but not…”
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Antidepressant-like effect of Ro5-4864, a peripheral-type benzodiazepine receptor ligand, in forced swimming test
Published in European journal of pharmacology (13-06-2003)“…This study examined the effects of peripheral-type benzodiazepine receptors in the forced swimming test. PK 11195 (1-(2-chloro-phenyl)- N-methyl-…”
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