Search Results - "De Legher, Carla"

Single-Cell RNA Sequencing Reveals Renal Endothelium Heterogeneity and Metabolic Adaptation to Water Deprivation by Dumas, Sébastien J, Meta, Elda, Borri, Mila, Goveia, Jermaine, Rohlenova, Katerina, Conchinha, Nadine V, Falkenberg, Kim, Teuwen, Laure-Anne, de Rooij, Laura, Kalucka, Joanna, Chen, Rongyuan, Khan, Shawez, Taverna, Federico, Lu, Weisi, Parys, Magdalena, De Legher, Carla, Vinckier, Stefan, Karakach, Tobias K, Schoonjans, Luc, Lin, Lin, Bolund, Lars, Dewerchin, Mieke, Eelen, Guy, Rabelink, Ton J, Li, Xuri, Luo, Yonglun, Carmeliet, Peter

“…Renal endothelial cells from glomerular, cortical, and medullary kidney compartments are exposed to different microenvironmental conditions and support…”
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Deletion or Inhibition of the Oxygen Sensor PHD1 Protects against Ischemic Stroke via Reprogramming of Neuronal Metabolism by Quaegebeur, Annelies, Segura, Inmaculada, Schmieder, Roberta, Verdegem, Dries, Decimo, Ilaria, Bifari, Francesco, Dresselaers, Tom, Eelen, Guy, Ghosh, Debapriva, Davidson, Shawn M., Schoors, Sandra, Broekaert, Dorien, Cruys, Bert, Govaerts, Kristof, De Legher, Carla, Bouché, Ann, Schoonjans, Luc, Ramer, Matt S., Hung, Gene, Bossaert, Goele, Cleveland, Don W., Himmelreich, Uwe, Voets, Thomas, Lemmens, Robin, Bennett, C. Frank, Robberecht, Wim, De Bock, Katrien, Dewerchin, Mieke, Ghesquière, Bart, Fendt, Sarah-Maria, Carmeliet, Peter

“…The oxygen-sensing prolyl hydroxylase domain proteins (PHDs) regulate cellular metabolism, but their role in neuronal metabolism during stroke is unknown. Here…”
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The gluconeogenesis enzyme PCK2 has a non-enzymatic role in proteostasis in endothelial cells by de Zeeuw, Pauline, Treps, Lucas, García-Caballero, Melissa, Harjes, Ulrike, Kalucka, Joanna, De Legher, Carla, Brepoels, Katleen, Peeters, Kristel, Vinckier, Stefan, Souffreau, Joris, Bouché, Ann, Taverna, Federico, Dehairs, Jonas, Talebi, Ali, Ghesquière, Bart, Swinnen, Johan, Schoonjans, Luc, Eelen, Guy, Dewerchin, Mieke, Carmeliet, Peter

“…Endothelial cells (ECs) are highly glycolytic, but whether they generate glycolytic intermediates via gluconeogenesis (GNG) in glucose-deprived conditions…”
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