Search Results - "De Leeuw, Astrid"
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1
Clinical Use of the Utrecht Applicator for Combined Intracavitary/Interstitial Brachytherapy Treatment in Locally Advanced Cervical Cancer
Published in International journal of radiation oncology, biology, physics (15-03-2012)“…Purpose The aims of this study were to investigate the benefit of the Utrecht interstitial CT/MR applicator for combined intracavitary/interstitial (IC/IS)…”
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2
Vaginal dose de-escalation in image guided adaptive brachytherapy for locally advanced cervical cancer
Published in Radiotherapy and oncology (01-09-2016)“…Abstract Purpose Vaginal stenosis is a major problem following radiotherapy in cervical cancer. We investigated a new dose planning strategy for vaginal dose…”
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3
Clinical outcome and dosimetric parameters of chemo-radiation including MRI guided adaptive brachytherapy with tandem-ovoid applicators for cervical cancer patients: A single institution experience
Published in Radiotherapy and oncology (01-04-2013)“…Abstract Purpose To evaluate dosimetric parameters and clinical outcome for cervical cancer patients treated with chemo-radiation and MR-image guided adaptive…”
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4
Dose-effect relationship between vaginal dose points and vaginal stenosis in cervical cancer: An EMBRACE-I sub-study
Published in Radiotherapy and oncology (01-03-2022)“…•Doses to the vaginal dose points predicts well the risk of vaginal morbidity.•Higher doses to the vaginal PIBS points are associated with vaginal stenosis.•A…”
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5
Multi-center dosimetric predictions to improve plan quality for brachytherapy for cervical cancer treatment
Published in Radiotherapy and oncology (01-05-2023)“…•Overlap volume histograms can be used for prediction models of D2cm3 values.•Prediction models can be used in a multi-center setting to detect suboptimal…”
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6
Implementing an online radiotherapy quality assurance programme with supporting continuous medical education – report from the EMBRACE-II evaluation of cervix cancer IMRT contouring
Published in Radiotherapy and oncology (01-06-2020)“…•Online RTQA with minimal data transfer is feasible and reduces manpower burden•Expert evaluation with qualitative feedback improved contouring compliance.•The…”
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7
Nodal failure after chemo-radiation and MRI guided brachytherapy in cervical cancer: Patterns of failure in the EMBRACE study cohort
Published in Radiotherapy and oncology (01-05-2019)“…•Nodal failure rate after chemo-radiation and MRI guided BT is 11%.•Nodal failure rates for the N− and N+ group were 7 and 16%•Complete remission after…”
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8
Management of Nodal Disease in Advanced Cervical Cancer
Published in Seminars in radiation oncology (01-04-2019)“…During the last decade the adoption of image-guided adaptive brachytherapy has dramatically improved local control in patients with locally advanced cervical…”
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Patterns of care survey: Radiotherapy for women with locally advanced cervical cancer
Published in Radiotherapy and oncology (01-05-2017)“…Abstract Background and purpose Regarding latest developments, the need of a radiotherapy ‘Patterns of Care’ survey was expressed by the Dutch National…”
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10
Risk factors for nodal failure after radiochemotherapy and image guided brachytherapy in locally advanced cervical cancer: An EMBRACE analysis
Published in Radiotherapy and oncology (01-10-2021)“…•Nodal disease, tumour width and local failure are risk factors for NF post-treatment for LACC.•Any CI nodes without PAO nodes’ and ‘any PAO nodes’ are…”
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11
MRI-guided treatment-planning optimisation in intracavitary or combined intracavitary/interstitial PDR brachytherapy using tandem ovoid applicators in locally advanced cervical cancer
Published in Radiotherapy and oncology (01-11-2009)“…Abstract Purpose To study the impact of MRI-guided treatment planning on dose/volume parameters in pulsed dose rate (PDR) brachytherapy (BT) for cervical…”
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12
Impact of radiation dose and standardized uptake value of (18)FDG PET on nodal control in locally advanced cervical cancer
Published in Acta oncologica (21-10-2015)“…Despite local control now exceeding 90% with image-guided adaptive brachytherapy (IGABT), regional and distant metastases continue to curb survival in locally…”
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13
Vaginal dose-surface maps in cervical cancer brachytherapy: Methodology and preliminary results on correlation with morbidity
Published in Brachytherapy (01-05-2021)“…The purpose of the study was to develop a methodology for vaginal dose-surface maps (DSMs) in patients with cervix cancer and to investigate dose-surface…”
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14
Intra-fraction uncertainties of MRI guided brachytherapy in patients with cervical cancer
Published in Radiotherapy and oncology (01-08-2014)“…Abstract Dosimetric intra-fraction uncertainties in MRI-guided brachytherapy were analysed for HR-CTV and OARs. While dose differences were generally small,…”
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15
Position shifts and volume changes of pelvic and para-aortic nodes during IMRT for patients with cervical cancer
Published in Radiotherapy and oncology (01-06-2014)“…Abstract Background and purpose To evaluate volume changes and position shifts and their contribution to treatment margins of pelvic and para-aortic lymph…”
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16
Applicator reconstruction and applicator shifts in 3D MR-based PDR brachytherapy of cervical cancer
Published in Radiotherapy and oncology (01-11-2009)“…Abstract Purpose To evaluate the methods of applicator reconstruction in 3D MR-based planning for brachytherapy of cervical cancer, and to investigate…”
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The feasibility of semi-automatically generated red bone marrow segmentations based on MR-only for patients with gynecologic cancer
Published in Radiotherapy and oncology (01-04-2017)“…Abstract Purpose For patients with cervical cancer the delivery of chemotherapy with radiotherapy improves survival compared with radiotherapy alone. However,…”
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18
Using the theory of planned behavior to identify key beliefs underlying pro-environmental behavior in high-school students: Implications for educational interventions
Published in Journal of environmental psychology (01-06-2015)“…This study relied on the theory of planned behavior (TPB) to identify the beliefs that influence young people's pro-environmental behavior. High-school…”
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Multicentre treatment planning study of MRI-guided brachytherapy for cervical cancer: Comparison between tandem-ovoid applicator users
Published in Radiotherapy and oncology (01-04-2013)“…Abstract Background and purpose To compare MRI-guided treatment planning approaches between four centres that use tandem-ovoid applicators. Material and…”
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The effect of alternative biological modelling parameters (α/β and half time of repair T1/2 ) on reported EQD2 values in the treatment of advanced cervical cancer
Published in Radiotherapy and oncology (01-11-2011)“…Abstract Purpose To evaluate the effect of different α/β and half-time of repair T½ on the assessment of clinical treatment plans for patients with cervical…”
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