Search Results - "De Leeuw, A."

Meta-analysis of the heritability of human traits based on fifty years of twin studies by Polderman, Tinca J C, Benyamin, Beben, de Leeuw, Christiaan A, Sullivan, Patrick F, van Bochoven, Arjen, Visscher, Peter M, Posthuma, Danielle

“…Danielle Posthuma, Peter Visscher and colleagues report a meta-analysis of 17,804 traits based on virtually all twin studies from the last 50 years. For a…”
Get full text

Genetic mapping of cell type specificity for complex traits by Watanabe, Kyoko, Umićević Mirkov, Maša, de Leeuw, Christiaan A., van den Heuvel, Martijn P., Posthuma, Danielle

“…Single-cell RNA sequencing (scRNA-seq) data allows to create cell type specific transcriptome profiles. Such profiles can be aligned with genome-wide…”
Get full text

MAGMA: generalized gene-set analysis of GWAS data by de Leeuw, Christiaan A, Mooij, Joris M, Heskes, Tom, Posthuma, Danielle

“…By aggregating data for complex traits in a biologically meaningful way, gene and gene-set analysis constitute a valuable addition to single-marker analysis…”
Get full text

Interaction effects on number fluctuations in a Bose-Einstein condensate of light by van der Wurff, E C I, de Leeuw, A-W, Duine, R A, Stoof, H T C

“…We investigate the effect of interactions on condensate-number fluctuations in Bose-Einstein condensates. For a contact interaction we variationally obtain the…”
Get full text

Anatomy of the ankle ligaments: a pictorial essay by Golanó, Pau, Vega, Jordi, de Leeuw, Peter A. J., Malagelada, Francesc, Manzanares, M. Cristina, Götzens, Víctor, van Dijk, C. Niek

“…Understanding the anatomy of the ankle ligaments is important for correct diagnosis and treatment. Ankle ligament injury is the most frequent cause of acute…”
Get full text

Genome-wide gene-environment interactions in neuroticism: an exploratory study across 25 environments by Werme, Josefin, van der Sluis, Sophie, Posthuma, Danielle, de Leeuw, Christiaan A.

“…Gene-environment interactions (GxE) are often suggested to play an important role in the aetiology of psychiatric phenotypes, yet so far, only a handful of…”
Get full text

Anatomy of the ankle ligaments: a pictorial essay by Golanó, Pau, Vega, Jordi, de Leeuw, Peter A. J., Malagelada, Francesc, Manzanares, M. Cristina, Götzens, Víctor, van Dijk, C. Niek

“…Understanding the anatomy of the ankle ligaments is important for correct diagnosis and treatment. Ankle ligament injury is the most frequent cause of acute…”
Get full text

Does activation of midbrain dopamine neurons promote or reduce feeding? by Boekhoudt, L, Roelofs, T J M, de Jong, J W, de Leeuw, A E, Luijendijk, M C M, Wolterink-Donselaar, I G, van der Plasse, G, Adan, R A H

“…Background: Dopamine (DA) signalling in the brain is necessary for feeding behaviour, and alterations in the DA system have been linked to obesity. However,…”
Get full text

The posterior fibulotalocalcaneal ligament complex: a forgotten ligament by De Leeuw, Peter A. J., Vega, Jordi, Karlsson, Jon, Dalmau-Pastor, Miki

“…Purpose The purpose of the present anatomical study was to define the exact morphology of the posterior fibulotalocalcaneal ligament complex (PFTCLC), both for…”
Get full text

Correction: Genome-wide gene-environment interactions in neuroticism: an exploratory study across 25 environments by Werme, Josefin, van der Sluis, Sophie, Posthuma, Danielle, de Leeuw, Christiaan A.

Get full text

Sonographic classification and reporting system for diagnosing adenomyosis by Van den Bosch, T., de Bruijn, A. M., de Leeuw, R. A., Dueholm, M., Exacoustos, C., Valentin, L., Bourne, T., Timmerman, D., Huirne, J. A. F.

Get full text

Author Correction: Genetic mapping of cell type specificity for complex traits by Watanabe, Kyoko, Mirkov, Maša Umićević, de Leeuw, Christiaan A., van den Heuvel, Martijn P., Posthuma, Danielle

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
Get full text

Correction to: Genome-wide gene-environment interactions in neuroticism: an exploratory study across 25 environments by Werme, Josefin, van der Sluis, Sophie, Posthuma, Danielle, de Leeuw, Christiaan A.

“…A Correction to this paper has been published: https://doi.org/10.1038/s41398-021-01334-6…”
Get full text

Gut Microbiota Composition Is Related to AD Pathology by Verhaar, Barbara J H, Hendriksen, Heleen M A, de Leeuw, Francisca A, Doorduijn, Astrid S, van Leeuwenstijn, Mardou, Teunissen, Charlotte E, Barkhof, Frederik, Scheltens, Philip, Kraaij, Robert, van Duijn, Cornelia M, Nieuwdorp, Max, Muller, Majon, van der Flier, Wiesje M

“…Several studies have reported alterations in gut microbiota composition of Alzheimer's disease (AD) patients. However, the observed differences are not…”
Get full text

Air-Liquid Interface Biofilms of Bacillus cereus: Formation, Sporulation, and Dispersion by Wijman, Janneke G.E, Leeuw, Patrick P.L.A. de, Moezelaar, Roy, Zwietering, Marcel H, Abee, Tjakko

“…Biofilm formation by Bacillus cereus was assessed using 56 strains of B. cereus, including the two sequenced strains, ATCC 14579 and ATCC 10987. Biofilm…”
Get full text

Conditional and interaction gene-set analysis reveals novel functional pathways for blood pressure by de Leeuw, Christiaan A., Stringer, Sven, Dekkers, Ilona A., Heskes, Tom, Posthuma, Danielle

“…Gene-set analysis provides insight into which functional and biological properties of genes are aetiologically relevant for a particular phenotype. But genes…”
Get full text

Associations of AD Biomarkers and Cognitive Performance with Nutritional Status: The NUDAD Project by Doorduijn, Astrid S, Visser, Marjolein, van de Rest, Ondine, Kester, Maartje I, de Leeuw, Francisca A, Boesveldt, Sanne, Fieldhouse, Jay L P, van den Heuvel, Ellen G H M, Teunissen, Charlotte E, Scheltens, Philip, van der Flier, Wiesje M, de van der Schueren, Marian A E

“…As malnutrition is common in patients with Alzheimer's disease (AD), we evaluated nutritional status and body composition of patients with AD, mild cognitive…”
Get full text

Genome-wide meta-analysis of brain volume identifies genomic loci and genes shared with intelligence by Jansen, Philip R., Nagel, Mats, Watanabe, Kyoko, Wei, Yongbin, Savage, Jeanne E., de Leeuw, Christiaan A., van den Heuvel, Martijn P., van der Sluis, Sophie, Posthuma, Danielle

“…The phenotypic correlation between human intelligence and brain volume (BV) is considerable ( r  ≈ 0.40), and has been shown to be due to shared genetic…”
Get full text

Hindfoot Endoscopy for Posterior Ankle Impingement: Surgical Technique by van Dijk, C.N, de Leeuw, P.A.J, Scholten, P.E

“…BACKGROUNDThe surgical treatment of posterior ankle impingement is associated with a high rate of complications and a substantial time to recover. An…”
Get full text

Rare variant aggregation in 148,508 exomes identifies genes associated with proxy dementia by Wightman, Douglas P., Savage, Jeanne E., de Leeuw, Christiaan A., Jansen, Iris E., Posthuma, Danielle

“…Proxy phenotypes allow for the utilization of genetic data from large population cohorts to analyze late-onset diseases by using parental diagnoses as a proxy…”
Get full text