Search Results - "De Léan, A"

Reduced Activity of the NPR-A Kinase Triggers Dephosphorylation and Homologous Desensitization of the Receptor by Joubert, Simon, Labrecque, Jean, De Léan, André

“…NPR-A, the receptor for the atrial natriuretic peptide (ANP), is a 130-kDa protein presenting an extracellular ANP-binding domain, a single transmembrane…”
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Comparative Effect of Pituitary Adenylate Cyclase-Activating Polypeptide on Aldosterone Secretion in Normal Bovine and Human Tumorous Adrenal Cells by Bodart, V., Babinski, K., Ong, H., De Léan, A.

“…Abstract The purpose of this study was to investigate the mechanisms of action of pituitary adenylate cyclase-activating polypeptide (PACAP) in stimulating…”
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A disulfide-bridged mutant of natriuretic peptide receptor-A displays constitutive activity. Role of receptor dimerization in signal transduction by Labrecque, J, Mc Nicoll, N, Marquis, M, De Léan, A

“…Natriuretic peptide receptor-A (NPR-A), a particulate guanylyl cyclase receptor, is composed of an extracellular domain (ECD) with a ligand binding site, a…”
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Characterization of Granulocyte-Macrophage Colony-Stimulating Factor Receptor on the Blast Cells of Acute Myeloblastic Leukemia by Onetto-Pothier, N., Aumont, N., Haman, A., Bigras, C., Wong, G.G., Clark, S.C., De Léan, A., Hoang, T.

“…Iodinated granulocyte-macrophage colony-stimulating factor (GM-CSF) was used to document the specific binding of GM-CSF to all acute myeloblastic leukemia…”
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Stoichiometry of the atrial natriuretic factor-R1 receptor complex in the bovine zona glomerulosa by Rondeau, J.-J, McNicoll, N, Gagnon, J, Bouchard, N, Ong, H, De Lean, A

“…The atrial natriuretic R1 receptor is a membrane protein that is present as an apparently preassociated noncovalent oligomer in the absence of ligand as…”
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Agonistic Induction of a Covalent Dimer in a Mutant of Natriuretic Peptide Receptor-A Documents a Juxtamembrane Interaction That Accompanies Receptor Activation by Labrecque, Jean, Deschênes, Julie, McNicoll, Normand, De Léan, André

“…The natriuretic peptide receptor-A (NPR-A) is composed of an extracellular domain with a ligand binding site, a transmembrane-spanning domain, a kinase…”
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Hydrodynamic properties of the angiotensin II receptor from bovine adrenal zona glomerulosa by Rondeau, J J, McNicoll, N, Escher, E, Meloche, S, Ong, H, De Léan, A

“…The bovine adrenal angiotensin II receptor was solubilized with the non-ionic detergent octyl beta-D-glucoside following its binding with the high-affinity…”
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A highly specific radioreceptor assay for the active circulating form of atrial natriuretic factor in human plasma by Ong, H, De Léan, A, Gagnon, C

“…This highly sensitive radioreceptor assay (RRA) for the active circulating form of atrial natriuretic factor (ANF), fragment 99-126, in human plasma requires…”
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Short-term inverse-agonist treatment induces reciprocal changes in delta-opioid agonist and inverse-agonist binding capacity by Piñeyro, G, Azzi, M, De Léan, A, Schiller, P, Bouvier, M

“…This study assessed the effects of short-term treatment (30-min) with inverse agonists on receptor protein levels and on the ability of agonists, inverse…”
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Atrial natriuretic factor binding sites in experimental congestive heart failure by Bianchi, C, Thibault, G, Wrobel-Konrad, E, De Léan, A, Genest, J, Cantin, M

“…A quantitative in vitro autoradiographic study was performed on the aorta, renal glomeruli, and adrenal cortex of cardiomyopathic hamsters in various stages of…”
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Effect of atrial natriuretic factor on corticosteroid production by perifused frog interrenal slices by Lihrmann, I, Netchitaïlo, P, Feuilloley, M, Cantin, M, Delarue, C, Leboulenger, F, De Léan, A, Vaudry, H

“…In order to investigate a possible role of atrial natriuretic factor (ANF) in the control of corticosteroid biosynthesis in amphibians, we have examined the…”
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Dopamine 3-sulfate inhibits aldosterone secretion in cultured bovine adrenal cells by Rácz, K, Buu, N T, Kuchel, O, De Léan, A

“…It has been demonstrated that dopamine inhibits the aldosterone (Aldo) secretion in bovine adrenal cells in vitro. Because the majority of the total…”
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Novel glucocorticoid receptor complex with DNA element of the hormone‐repressed POMC gene by Drouin, J., Sun, Y.L., Chamberland, M., Gauthier, Y., De Léan, A., Nemer, M., Schmidt, T.J.

“…Previous studies defined a DNA element necessary for glucocorticoid repression of the pro‐opiomelanocortin (POMC) gene. The glucocorticoid receptor (GR) binds…”
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Identification of aldosterone secretion inhibitory factor in bovine adrenal medulla by De Léan, A, Ong, H, McNicoll, N, Racz, R, Gutkowska, J, Cantin, M

“…We report the first demonstration of an Aldosterone Secretion Inhibitory Factor (ASIF) in acid extracts of bovine adrenal medulla. Following separation from…”
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A ternary complex model explains the agonist-specific binding properties of the adenylate cyclase-coupled beta-adrenergic receptor by De Lean, A, Stadel, J M, Lefkowitz, R J

“…The unique properties of agonist binding to the frog erythrocyte beta-adrenergic receptor include the existence of two affinity forms of the receptor. The…”
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Comparative binding study of rat natriuretic peptide receptor-A by Marquis, M, Fenrick, R, Pedro, L, Bouvier, M, De Léan, A

“…The natriuretic peptide receptor-A (NPR-A) is involved in blood pressure and body fluid regulation in order to help maintain cardiovascular homeostasis. It has…”
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Development of p-benzoylbenzoylated [N,C,rANP(1-28)]pBNP32 (pBNP1) derivatives and affinity photolabeling of the bovine NPR-A receptor by Coupal, M, De Léan, A, McNicoll, N, Fournier, A

“…Two Nalpha-benzophenone-substituted photoprobes, derived from the high affinity NPR-A chimeric agonist [N, C, rANP(1-28)]pBNP32 (pBNP1) were assembled by…”
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Natriuretic peptides inhibit nicotine-induced whole-cell currents and catecholamine secretion in bovine chromaffin cells: evidence for the involvement of the atrial natriuretic factor R2 receptors by Babinski, K, Haddad, P, Vallerand, D, McNicoll, N, de Léan, A, Ong, H

“…There is increasing evidence that members of the natriuretic peptide family display sympathoinhibitory activity, but it remains uncertain which receptor…”
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The H295R human adrenocortical cell line contains functional atrial natriuretic peptide receptors that inhibit aldosterone biosynthesis by Bodart, V., Rainey, W.E., Fournier, A., Ong, H., De Léan, A.

“…The inhibitory effect of atrial natriuretic peptide (ANP) on angiotensin II (AII)-stimulated aldosterone secretion has been previously studied in rat and…”
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Characterization of the phosphorylation state of natriuretic peptide receptor-C by Pedro, L, Fenrick, R, Marquis, M, McNicoll, N, De Léan, A

“…Many internalized receptors are known to be phosphorylated within their cytoplasmic domain. Natriuretic peptide receptor-C (NPR-C) is a covalent homodimer…”
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