Search Results - "De La Torre, Carolina"

Epigenetic loss of RNA-methyltransferase NSUN5 in glioma targets ribosomes to drive a stress adaptive translational program by Janin, Maxime, Ortiz-Barahona, Vanessa, de Moura, Manuel Castro, Martínez-Cardús, Anna, Llinàs-Arias, Pere, Soler, Marta, Nachmani, Daphna, Pelletier, Joffrey, Schumann, Ulrike, Calleja-Cervantes, Maria E., Moran, Sebastian, Guil, Sonia, Bueno-Costa, Alberto, Piñeyro, David, Perez-Salvia, Montserrat, Rosselló-Tortella, Margalida, Piqué, Laia, Bech-Serra, Joan J., De La Torre, Carolina, Vidal, August, Martínez-Iniesta, María, Martín-Tejera, Juan F., Villanueva, Alberto, Arias, Alexandra, Cuartas, Isabel, Aransay, Ana M., La Madrid, Andres Morales, Carcaboso, Angel M., Santa-Maria, Vicente, Mora, Jaume, Fernandez, Agustin F., Fraga, Mario F., Aldecoa, Iban, Pedrosa, Leire, Graus, Francesc, Vidal, Noemi, Martínez-Soler, Fina, Tortosa, Avelina, Carrato, Cristina, Balañá, Carme, Boudreau, Matthew W., Hergenrother, Paul J., Kötter, Peter, Entian, Karl-Dieter, Hench, Jürgen, Frank, Stephan, Mansouri, Sheila, Zadeh, Gelareh, Dans, Pablo D., Orozco, Modesto, Thomas, George, Blanco, Sandra, Seoane, Joan, Preiss, Thomas, Pandolfi, Pier Paolo, Esteller, Manel

“…Tumors have aberrant proteomes that often do not match their corresponding transcriptome profiles. One possible cause of this discrepancy is the existence of…”
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"Exosomics"-A Review of Biophysics, Biology and Biochemistry of Exosomes With a Focus on Human Breast Milk by de la Torre Gomez, Carolina, Goreham, Renee V, Bech Serra, Joan J, Nann, Thomas, Kussmann, Martin

“…Exosomes are biomolecular nanostructures released from cells. They carry specific biomolecular information and are mainly researched for their exquisite…”
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Liver sinusoidal endothelial cells orchestrate NK cell recruitment and activation in acute inflammatory liver injury by Papaioannou, Sophia, See, Jia-Xiang, Jeong, Mingeum, De La Torre, Carolina, Ast, Volker, Reiners-Koch, Philipp-Sebastian, Sati, Ankita, Mogler, Carolin, Platten, Michael, Cerwenka, Adelheid, Stojanovic, Ana

“…Liver sinusoidal endothelial cells (LSECs) rapidly clear lipopolysaccharide (LPS) from the bloodstream and establish intimate contact with immune cells…”
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Bone marrow sinusoidal endothelium controls terminal erythroid differentiation and reticulocyte maturation by Heil, Joschka, Olsavszky, Victor, Busch, Katrin, Klapproth, Kay, de la Torre, Carolina, Sticht, Carsten, Sandorski, Kajetan, Hoffmann, Johannes, Schönhaber, Hiltrud, Zierow, Johanna, Winkler, Manuel, Schmid, Christian David, Staniczek, Theresa, Daniels, Deborah E., Frayne, Jan, Metzgeroth, Georgia, Nowak, Daniel, Schneider, Sven, Neumaier, Michael, Weyer, Vanessa, Groden, Christoph, Gröne, Hermann-Josef, Richter, Karsten, Mogler, Carolin, Taketo, Makoto Mark, Schledzewski, Kai, Géraud, Cyrill, Goerdt, Sergij, Koch, Philipp-Sebastian

“…Within the bone marrow microenvironment, endothelial cells (EC) exert important functions. Arterial EC support hematopoiesis while H-type capillaries induce…”
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Inhibition of CBP synergizes with the RNA-dependent mechanisms of Azacitidine by limiting protein synthesis by Diesch, Jeannine, Le Pannérer, Marguerite-Marie, Winkler, René, Casquero, Raquel, Muhar, Matthias, van der Garde, Mark, Maher, Michael, Herráez, Carolina Martínez, Bech-Serra, Joan J., Fellner, Michaela, Rathert, Philipp, Brooks, Nigel, Zamora, Lurdes, Gentilella, Antonio, de la Torre, Carolina, Zuber, Johannes, Götze, Katharina S., Buschbeck, Marcus

“…The nucleotide analogue azacitidine (AZA) is currently the best treatment option for patients with high-risk myelodysplastic syndromes (MDS). However, only…”
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miRWalk: An online resource for prediction of microRNA binding sites by Sticht, Carsten, De La Torre, Carolina, Parveen, Alisha, Gretz, Norbert

“…miRWalk is an open-source platform providing an intuitive interface that generates predicted and validated miRNA-binding sites of known genes of human, mouse,…”
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SIRT6-dependent cysteine monoubiquitination in the PRE-SET domain of Suv39h1 regulates the NF-κB pathway by Santos-Barriopedro, Irene, Bosch-Presegué, Laia, Marazuela-Duque, Anna, de la Torre, Carolina, Colomer, Carlota, Vazquez, Berta N., Fuhrmann, Thomas, Martínez-Pastor, Bárbara, Lu, Wenfu, Braun, Thomas, Bober, Eva, Jenuwein, Thomas, Serrano, Lourdes, Esteller, Manel, Chen, Zhenbang, Barceló-Batllori, Silvia, Mostoslavsky, Raúl, Espinosa, Lluis, Vaquero, Alejandro

“…Sirtuins are NAD + -dependent deacetylases that facilitate cellular stress response. They include SirT6, which protects genome stability and regulates…”
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New Insights into the Exosome-Induced Migration of Uveal Melanoma Cells and the Pre-Metastatic Niche Formation in the Liver by Ramos, Raquel, Vinyals, Antònia, Campos-Martin, Rafael, Cabré, Eduard, Bech, Joan Josep, Vaquero, Javier, Gonzalez-Sanchez, Ester, Bertran, Esther, Ferreres, Josep Ramon, Lorenzo, Daniel, De La Torre, Carolina G, Fabregat, Isabel, Caminal, Jose Maria, Fabra, Àngels

“…UM is an aggressive intraocular tumor characterized by high plasticity and a propensity to metastasize in the liver. However, the underlying mechanisms…”
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A Case of Plasmablastic Multiple Myeloma With Extramedullary Disease Manifesting as a Myelomatous Pleural Effusion by Mohamed Jiffry, Mohamed Zakee, Ahmed-Khan, Mohammad, Rangsipat, Napat, Galligani, Lauren, De La Torre, Carolina

“…Multiple myeloma (MM) is a neoplasm of plasma cell origin characterized by the proliferation of immunoglobulin-producing plasma cells in the bone marrow…”
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NFAT5/TonEBP Limits Pulmonary Vascular Resistance in the Hypoxic Lung by Controlling Mitochondrial Reactive Oxygen Species Generation in Arterial Smooth Muscle Cells by Laban, Hebatullah, Siegmund, Sophia, Zappe, Maren, Trogisch, Felix A, Heineke, Jörg, Torre, Carolina De La, Fisslthaler, Beate, Arnold, Caroline, Lauryn, Jonathan, Büttner, Michael, Mogler, Carolin, Kato, Katsuhiro, Adams, Ralf H, Kuk, Hanna, Fischer, Andreas, Hecker, Markus, Kuebler, Wolfgang M, Korff, Thomas

“…Chronic hypoxia increases the resistance of pulmonary arteries by stimulating their contraction and augmenting their coverage by smooth muscle cells (SMCs)…”
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Identification of 15 novel partial SHOX deletions and 13 partial duplications, and a review of the literature reveals intron 3 to be a hotspot region by Benito-Sanz, Sara, Belinchon-Martínez, Alberta, Aza-Carmona, Miriam, de la Torre, Carolina, Huber, Celine, González-Casado, Isabel, Ross, Judith L, Thomas, N Simon, Zinn, Andrew R, Cormier-Daire, Valerie, Heath, Karen E

“…Short stature homeobox gene (SHOX) is located in the pseudoautosomal region 1 of the sex chromosomes. It encodes a transcription factor implicated in the…”
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Evaluation of Tumor Interstitial Fluid-Extraction Methods for Proteome Analysis: Comparison of Biopsy Elution versus Centrifugation by Matas-Nadal, Clara, Bech-Serra, Joan Josep, Guasch-Vallés, Marta, Fernández-Armenteros, Josep Manel, Barceló, Carla, Casanova, Josep Manel, de la Torre Gómez, Carolina, Aguayo Ortiz, Rafael, Garí, Eloi

“…The analysis of tumor interstitial fluid (TIF) composition is a valuable procedure to identify antimetastatic targets, and different laboratories have set up…”
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Inhibition of miR30a-3p by sulforaphane enhances gap junction intercellular communication in pancreatic cancer by Georgikou, Christina, Yin, Libo, Gladkich, Jury, Xiao, Xi, Sticht, Carsten, Torre, Carolina de la, Gretz, Norbert, Gross, Wolfgang, Schäfer, Michael, Karakhanova, Svetlana, Herr, Ingrid

“…The therapy resistance of pancreatic cancer is associated with the loss of gap junction intercellular communication and connexin 43 expression. The broccoli…”
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YAP-dependent induction of UHMK1 supports nuclear enrichment of the oncogene MYBL2 and proliferation in liver cancer cells by Wei, Teng, Weiler, Sofia Maria Elisabeth, Tóth, Marcell, Sticht, Carsten, Lutz, Teresa, Thomann, Stefan, De La Torre, Carolina, Straub, Beate, Merker, Sabine, Ruppert, Thomas, Marquardt, Jens, Singer, Stephan, Gretz, Norbert, Schirmacher, Peter, Breuhahn, Kai

“…The oncogene yes-associated protein (YAP) is a key modifier of liver homeostasis and regulates mitosis in hepatocytes as well as in malignantly transformed…”
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NOTCH target gene HES5 mediates oncogenic and tumor suppressive functions in hepatocarcinogenesis by Luiken, Sarah, Fraas, Angelika, Bieg, Matthias, Sugiyanto, Raisatun, Goeppert, Benjamin, Singer, Stephan, Ploeger, Carolin, Warsow, Gregor, Marquardt, Jens U., Sticht, Carsten, De La Torre, Carolina, Pusch, Stefan, Mehrabi, Arianeb, Gretz, Norbert, Schlesner, Matthias, Eils, Roland, Schirmacher, Peter, Longerich, Thomas, Roessler, Stephanie

“…NOTCH receptor signaling plays a pivotal role in liver homeostasis and hepatocarcinogenesis. However, the role of NOTCH pathway mutations and the NOTCH target…”
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ADP secreted by dying melanoma cells mediates chemotaxis and chemokine secretion of macrophages via the purinergic receptor P2Y12 by Kloss, Loreen, Dollt, Claudia, Schledzewski, Kai, Krewer, Andreas, Melchers, Susanne, Manta, Calin, Sticht, Carsten, Torre, Carolina de la, Utikal, Jochen, Umansky, Viktor, Schmieder, Astrid

“…Melanoma immunotherapy is still not satisfactory due to immunosuppressive cell populations within the tumor stroma. Targeting tumor-associated macrophages…”
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Sphingolipid desaturase DEGS1 is essential for mitochondria-associated membrane integrity by Planas-Serra, Laura, Launay, Nathalie, Goicoechea, Leire, Heron, Bénédicte, Jou, Cristina, Juliá-Palacios, Natalia, Ruiz, Montserrat, Fourcade, Stéphane, Casasnovas, Carlos, De La Torre, Carolina, Gelot, Antoinette, Marsal, Maria, Loza-Alvarez, Pablo, García-Cazorla, Àngels, Fatemi, Ali, Ferrer, Isidre, Portero-Otin, Manel, Area-Gómez, Estela, Pujol, Aurora

“…Sphingolipids function as membrane constituents and signaling molecules, with crucial roles in human diseases, from neurodevelopmental disorders to cancer,…”
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YAP Orchestrates Heterotypic Endothelial Cell Communication via HGF/c-MET Signaling in Liver Tumorigenesis by Thomann, Stefan, Weiler, Sofia M E, Marquard, Simone, Rose, Fabian, Ball, Claudia R, Tóth, Marcell, Wei, Teng, Sticht, Carsten, Fritzsche, Sarah, Roessler, Stephanie, De La Torre, Carolina, Ryschich, Eduard, Ermakova, Olga, Mogler, Carolin, Kazdal, Daniel, Gretz, Norbert, Glimm, Hanno, Rempel, Eugen, Schirmacher, Peter, Breuhahn, Kai

“…The oncogene yes-associated protein (YAP) controls liver tumor initiation and progression via cell extrinsic functions by creating a tumor-supporting…”
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SIRT1 regulates DNA damage signaling through the PP4 phosphatase complex by Rasti, George, Becker, Maximilian, Vazquez, Berta N, Espinosa-Alcantud, Maria, Fernández-Duran, Irene, Gámez-García, Andrés, Ianni, Alessandro, Gonzalez, Jessica, Bosch-Presegué, Laia, Marazuela-Duque, Anna, Guitart-Solanes, Anna, Segura-Bayona, Sandra, Bech-Serra, Joan-Josep, Scher, Michael, Serrano, Lourdes, Shankavaram, Uma, Erdjument-Bromage, Hediye, Tempst, Paul, Reinberg, Danny, Olivella, Mireia, Stracker, Travis H, de la Torre, Carolina, Vaquero, Alejandro

“…Abstract The Sirtuin family of NAD+-dependent enzymes plays an important role in maintaining genome stability upon stress. Several mammalian Sirtuins have been…”
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Corrigendum to: “Nanosilver inhibits the progression of pancreatic cancer by inducing a paraptosis-like mixed type of cell death” [Biomed. Pharmacother. 153 (2022) 113511] by Liu, Li, An, XueFeng, Schaefer, Michael, Yan, Bin, de la Torre, Carolina, Hillmer, Stefan, Gladkich, Jury, Herr, Ingrid

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