Search Results - "De La Motte, Stephan"
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Cardiac safety of Modified Vaccinia Ankara for vaccination against smallpox in a young, healthy study population
Published in PloS one (16-04-2015)“…Conventional smallpox vaccines based on replicating vaccinia virus (VV) strains (e.g. Lister Elstree, NYCBOH) are associated with a high incidence of…”
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Omalizumab protects against allergen- induced bronchoconstriction in allergic (immunoglobulin E-mediated) asthma
Published in International archives of allergy and immunology (01-01-2013)“…Omalizumab has been shown to suppress responses to inhaled allergens in allergic asthma patients with pretreatment immunoglobulin E (IgE) ≤700 IU/ml. To extend…”
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Pharmacokinetics of multiple inhaled NVA237 doses in patients with chronic obstructive pulmonary disease (COPD)
Published in International journal of clinical pharmacology and therapeutics (01-02-2012)“…NVA237 (glycopyrronium bromide) is a once-daily longacting muscarinic antagonist (LAMA) in development for the treatment of chronic obstructive pulmonary…”
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Pharmacokinetic and pharmacodynamic comparison of subcutaneous versus intramuscular leuprolide acetate formulations in male subjects
Published in Therapeutic advances in urology (01-02-2018)“…Background: The aim of this study was to compare the pharmacokinetics (PK) and pharmacodynamics (PD) of two distinct formulations of leuprolide acetate (LA);…”
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Pharmacokinetics and safety of aclidinium bromide in younger and elderly patients with chronic obstructive pulmonary disease
Published in International journal of clinical pharmacology and therapeutics (01-06-2012)“…To investigate the pharmacokinetics, safety and tolerability of aclidinium bromide 200 μg and 400 μg after a single dose and repeated once-daily doses in…”
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Evaluation of the CCK-4 model as a challenge paradigm in a population of healthy volunteers within a proof-of-concept study
Published in Psychopharmacologia (01-07-2007)“…Experimental panic induction with cholecystokinin-tetrapeptide (CCK-4) has been established as a model to study the pathophysiology of panic disorder and might…”
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Effects of Consumption of a Fermented Dairy Product Containing the Probiotic Lactobacillus casei DN-114 001 on Common Respiratory and Gastrointestinal Infections in Shift Workers in a Randomized Controlled Trial
Published in Journal of the American College of Nutrition (01-10-2010)“…Objective: The risk of infection may be increased in people under stress such as shift workers. This study examined the effect of a fermented dairy product…”
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Reduction of dietary fat absorption by the novel gastrointestinal lipase inhibitor cetilistat in healthy volunteers
Published in British journal of clinical pharmacology (01-03-2009)“…WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT • Obesity is a significant and growing problem for which many patients seek pharmacological intervention. • Orlistat,…”
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Randomized head-to-head prospective study of pharmacokinetic and pharmacodynamic properties of leuprolide acetate formulations: 7.5 mg single depot subcutaneous vs 7.5 mg intramuscular microsphere
Published in Journal of clinical oncology (20-05-2015)“…Abstract only…”
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Comparative Pharmacokinetics and Pharmacodynamics of a New Sustained-Release Growth Hormone (GH), LB03002, Versus Daily GH in Adults with GH Deficiency
Published in The journal of clinical endocrinology and metabolism (01-08-2006)“…Context: LB03002 is a novel sustained-release GH preparation administered once weekly. Objective: Our objective was to examine the pharmacokinetics,…”
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Pharmacokinetic and pharmacodynamic comparison of subcutaneous intramuscular leuprolide acetate formulations in male subjects
Published in Therapeutic advances in urology (01-02-2018)“…Background: The aim of this study was to compare the pharmacokinetics (PK) and pharmacodynamics (PD) of two distinct formulations of leuprolide acetate (LA);…”
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Effects of bicarbonate- and lactate-buffered replacement fluids on cardiovascular outcome in CVVH patients
Published in Kidney international (01-10-2000)“…Effects of bicarbonate- and lactate-buffered replacement fluids on cardiovascular outcome in CVVH patients. Bicarbonate-buffered replacement fluid (RF-bic) in…”
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Hemodynamic effects of intravenous elgodipine in coronary artery disease during rest and exercise, and basic pharmacokinetic parameters
Published in Cardiovascular drugs and therapy (01-11-1996)“…Using an echo-Doppler method (Quantascope), the hemodynamic profile of the calcium channel antagonist elgodipine (64 micrograms/kg, i.v.) was investigated in…”
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Investigation of the efficacy of oxerutins compared to placebo in patients with chronic venous insufficiency treated with compression stockings
Published in Arzneimittel-Forschung (01-05-1996)“…The aim of this study was to investigate, if the the combined treatment of compression stockings and drug treatment with oxerutins…”
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Pharmacokinetics of Human Growth Hormone Administered Subcutaneously with two Different Injection Systems
Published in Arzneimittel-Forschung (01-01-2001)“…Summary The bioavailability of recombinant human growth hormone (somatropin, CAS 12629-01-5) was compared between a transcutaneous jet injection device and…”
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