Search Results - "De La Fuente, Hortensia"

Thymus-Derived Regulatory T Cell Development Is Regulated by C-Type Lectin-Mediated BIC/MicroRNA 155 Expression by Sánchez-Díaz, Raquel, Blanco-Dominguez, Rafael, Lasarte, Sandra, Tsilingiri, Katerina, Martín-Gayo, Enrique, Linillos-Pradillo, Beatriz, de la Fuente, Hortensia, Sánchez-Madrid, Francisco, Nakagawa, Rinako, Toribio, María L., Martín, Pilar

“…Thymus-derived regulatory T (tTreg) cells are key to preventing autoimmune diseases, but the mechanisms involved in their development remain unsolved. Here, we…”
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Influence of air pollutants on circulating inflammatory cells and microRNA expression in acute myocardial infarction by Cecconi, Alberto, Navarrete, Gonzalo, Garcia-Guimaraes, Marcos, Vera, Alberto, Blanco-Dominguez, Rafael, Sanz-Garcia, Ancor, Lozano-Prieto, Marta, Lopez-Melgar, Beatriz, Rivero, Fernando, Martin, Pilar, Sanchez-Madrid, Francisco, de la Fuente, Hortensia, Jimenez-Borreguero, Luis Jesus, Alfonso, Fernando

“…Air pollutants increase the risk and mortality of myocardial infarction (MI). The aim of this study was to assess the inflammatory changes in circulating…”
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Growth arrest and DNA damage-inducible proteins (GADD45) in psoriasis by Rodríguez-Jiménez, Pedro, Fernández-Messina, Lola, Ovejero-Benito, María C., Chicharro, Pablo, Vera-Tomé, Paula, Vara, Alicia, Cibrian, Danay, Martínez-Fleta, Pedro, Jiménez-Fernández, María, Sánchez-García, Inés, Llamas-Velasco, Mar, Abad-Santos, Francisco, Sánchez-Madrid, Francisco, Dauden, Esteban, de la Fuente, Hortensia

“…The interplay between T cells, dendritic cells and keratinocytes is crucial for the development and maintenance of inflammation in psoriasis. GADD45 proteins…”
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Utility of circulating serum miRNA profiles to evaluate the potential risk and severity of immune-mediated inflammatory disorders by Martínez-Hernández, Rebeca, Fuente, Hortensia de la, Lamana, Amalia, Sampedro-Núñez, Miguel, Ramos-Levi, Ana, Serrano-Somavilla, Ana, García-Vicuña, Rosario, Ortiz, Ana M., Daudén, Esteban, Llamas-Velasco, Mar, Chicharro, Pablo, Rodríguez-Jiménez, Pedro, Sanz-García, Ancor, Sánchez-Madrid, Francisco, González-Álvaro, Isidoro, Marazuela, Mónica

“…Immune-mediated inflammatory disorders (IMID) are a group of diseases that present inflammation as a major pathogenic mechanism. They affect 15% of the…”
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Galectin-1: A Potential Biomarker Differentiating between Early Rheumatoid Arthritis and Spondyloarthritis by Triguero-Martínez, Ana, Roy-Vallejo, Emilia, Tomero, Eva Gloria, Montes, Nuria, Fuente, Hortensia de la, Ortiz, Ana María, Castañeda, Santos, Lamana, Amalia, González-Álvaro, Isidoro

“…Galectin-1 (Gal1) plays a regulatory role in the immune system. We have recently validated that Gal1 serum (sGal1) levels are increased in rheumatoid arthritis…”
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The leukocyte activation antigen CD69 limits allergic asthma and skin contact hypersensitivity by Martín, Pilar, PhD, Gómez, Manuel, PhD, Lamana, Amalia, PhD, Marín, Adela Matesanz, Cortés, José R., PhD, Ramírez-Huesca, Marta, Barreiro, Olga, PhD, López-Romero, Pedro, PhD, Gutiérrez-Vázquez, Cristina, de la Fuente, Hortensia, MD, PhD, Cruz-Adalia, Aránzazu, Sánchez-Madrid, Francisco, PhD

“…Background Allergic diseases have a major health care impact in industrialized countries. The development of these diseases is influenced by exposure to…”
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Inflammation biomarkers in blood as mortality predictors in community-acquired pneumonia admitted patients: Importance of comparison with neutrophil count percentage or neutrophil-lymphocyte ratio by Curbelo, Jose, Luquero Bueno, Sergio, Galván-Román, José María, Ortega-Gómez, Mara, Rajas, Olga, Fernández-Jiménez, Guillermo, Vega-Piris, Lorena, Rodríguez-Salvanes, Francisco, Arnalich, Belén, Díaz, Ana, Costa, Ramón, de la Fuente, Hortensia, Lancho, Ángel, Suárez, Carmen, Ancochea, Julio, Aspa, Javier

“…The increase and persistence of inflammation in community-acquired pneumonia (CAP) patients can lead to higher mortality. Biomarkers capable of measuring this…”
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CD69 expression on regulatory T cells protects from immune damage after myocardial infarction by Blanco-Dominguez, Rafael, de la Fuente, Hortensia, Rodriguez, Cristina, Martin-Aguado, Laura, Sanchez-Diaz, Raquel, Jimenez-Alejandre, Rosa, Rodriguez-Arabaolaza, Iker, Curtabbi, Andrea, Garcia-Guimaraes, Marcos M, Vera, Alberto, Rivero, Fernando, Cuesta, Javier, Jimenez-Borreguero, Luis J, Cecconi, Alberto, Duran-Cambra, Albert, Tauron, Manel, Alonso, Judith, Bueno, Hector, Villalba-Orero, Maria, Enriquez, Jose Antonio, Robson, Simon C, Alfonso, Fernando, Sanchez-Madrid, Francisco, Martinez-Gonzalez, Jose, Martin, Pilar

“…Increasing evidence has pointed to the important function of T cells in controlling immune homeostasis and pathogenesis after myocardial infarction (MI),…”
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CD69 controls the uptake of L-tryptophan through LAT1-CD98 and AhR-dependent secretion of IL-22 in psoriasis by Cibrian, Danay, Saiz, María Laura, de la Fuente, Hortensia, Sánchez-Díaz, Raquel, Moreno-Gonzalo, Olga, Jorge, Inmaculada, Ferrarini, Alessia, Vázquez, Jesús, Punzón, Carmen, Fresno, Manuel, Vicente-Manzanares, Miguel, Daudén, Esteban, Fernández-Salguero, Pedro M, Martín, Pilar, Sánchez-Madrid, Francisco

“…Sanchez-Madrid and colleagues show that CD69 associates with the amino acid transporter LAT1-CD98 to control the uptake of tryptophan and AhR-dependent…”
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Immunomodulatory role of microRNAs transferred by extracellular vesicles by Fernández-Messina, Lola, Gutiérrez-Vázquez, Cristina, Rivas-García, Eva, Sánchez-Madrid, Francisco, de la Fuente, Hortensia

“…The immune system is composed of different cell types localised throughout the organism to sense and respond to pathological situations while maintaining…”
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A MicroRNA Signature for Evaluation of Risk and Severity of Autoimmune Thyroid Diseases by Martínez-Hernández, Rebeca, Sampedro-Núñez, Miguel, Serrano-Somavilla, Ana, Ramos-Leví, Ana M, de la Fuente, Hortensia, Triviño, Juan Carlos, Sanz-García, Ancor, Sánchez-Madrid, Francisco, Marazuela, Mónica

“…Circulating microRNAs (miRNAs) are emerging as an interesting research area because of their potential role as novel biomarkers and therapeutic targets. Their…”
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The impact of type 2 immunity and allergic diseases in atherosclerosis by Fernández‐Gallego, Nieves, Castillo‐González, Raquel, Méndez‐Barbero, Nerea, López‐Sanz, Celia, Obeso, David, Villaseñor, Alma, Escribese, María M., López‐Melgar, Beatriz, Salamanca, Jorge, Benedicto‐Buendía, Amparo, Jiménez‐Borreguero, Luis Jesús, Ibañez, Borja, Sastre, Joaquín, Belver, María Teresa, Vega, Francisco, Blanco, Carlos, Barber, Domingo, Sánchez‐Madrid, Francisco, Fuente, Hortensia, Martín, Pilar, Esteban, Vanesa, Jiménez‐Saiz, Rodrigo

“…Allergic diseases are allergen‐induced immunological disorders characterized by the development of type 2 immunity and IgE responses. The prevalence of…”
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The double injection technique to improve visualization of severe coronary lesions with optical coherence tomography by Rivero, Fernando, Marco, Valeria, Biccirè, Flavio Giuseppe, Budassi, Simone, Cuesta, Javier, Val, David, Bastante, Teresa, Fuente, Hortensia, Prati, Francesco, Alfonso, Fernando

“…Background Optical coherence tomography (OCT) is a high‐resolution imaging modality that provides a precise evaluation of coronary anatomy. However, the…”
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The Leukocyte Activation Receptor CD69 Controls T Cell Differentiation through Its Interaction with Galectin-1 by de la Fuente, Hortensia, Cruz-Adalia, Aranzazu, Martinez del Hoyo, Gloria, Cibrián-Vera, Danay, Bonay, Pedro, Pérez-Hernández, Daniel, Vázquez, Jesús, Navarro, Pilar, Gutierrez-Gallego, Ricardo, Ramirez-Huesca, Marta, Martín, Pilar, Sánchez-Madrid, Francisco

“…CD69 is involved in immune cell homeostasis, regulating the T cell-mediated immune response through the control of Th17 cell differentiation. However, natural…”
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Usefulness of circulating microRNAs miR-146a and miR-16-5p as prognostic biomarkers in community-acquired pneumonia by Galván-Román, José María, Lancho-Sánchez, Ángel, Luquero-Bueno, Sergio, Vega-Piris, Lorena, Curbelo, Jose, Manzaneque-Pradales, Marcos, Gómez, Manuel, de la Fuente, Hortensia, Ortega-Gómez, Mara, Aspa, Javier

“…Patients with community-acquired pneumonia (CAP) undergo a dysregulated host response that is related to mortality. MicroRNAs (miRNAs) participate in this…”
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Deregulated cellular circuits driving immunoglobulins and complement consumption associate with the severity of COVID‐19 patients by Marcos‐Jiménez, Ana, Sánchez‐Alonso, Santiago, Alcaraz‐Serna, Ana, Esparcia, Laura, López‐Sanz, Celia, Sampedro‐Núñez, Miguel, Mateu‐Albero, Tamara, Sánchez‐Cerrillo, Ildefonso, Martínez‐Fleta, Pedro, Gabrie, Ligia, Campo Guerola, Luciana, Rodríguez‐Frade, José Miguel, Casasnovas, José M., Reyburn, Hugh T., Valés‐Gómez, Mar, López‐Trascasa, Margarita, Martín‐Gayo, Enrique, Calzada, María José, Castañeda, Santos, Fuente, Hortensia, González‐Álvaro, Isidoro, Sánchez‐Madrid, Francisco, Muñoz‐Calleja, Cecilia, Alfranca, Arantzazu

“…SARS‐CoV‐2 infection causes an abrupt response by the host immune system, which is largely responsible for the outcome of COVID‐19. We investigated whether the…”
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MICa/b‐dependent activation of natural killer cells by CD64+ inflammatory type 2 dendritic cells contributes to autoimmunity by Sánchez‐Cerrillo, Ildefonso, Calzada‐Fraile, Diego, Triguero‐Martínez, Ana, Calvet‐Mirabent, Marta, Popova, Olga, Delgado‐Arévalo, Cristina, Valdivia‐Mazeyra, Mariel, Ramírez‐Huesca, Marta, Luis, Enrique Vázquez, Benguría, Alberto, Aceña‐Gonzalo, Teresa, Moreno‐Vellisca, Roberto, Llano, Magdalena Adrados, Fuente, Hortensia, Tsukalov, Ilya, Delgado‐Wicke, Pablo, Fernández‐Ruiz, Elena, Roy‐Vallejo, Emilia, Tejedor‐Lázaro, Reyes, Ramiro, Almudena, Iborra, Salvador, Sánchez‐Madrid, Francisco, Dopazo, Ana, Álvaro, Isidoro González, Castañeda, Santos, Martin‐Gayo, Enrique

“…Primary Sjögren's syndrome (pSS) is an inflammatory autoimmune disorder largely mediated by type I and II interferon (IFN). The potential contribution of…”
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A Differential Signature of Circulating miRNAs and Cytokines Between COVID-19 and Community-Acquired Pneumonia Uncovers Novel Physiopathological Mechanisms of COVID-19 by Martínez-Fleta, Pedro, Vera-Tomé, Paula, Jiménez-Fernández, María, Requena, Silvia, Roy-Vallejo, Emilia, Sanz-García, Ancor, Lozano-Prieto, Marta, López-Sanz, Celia, Vara, Alicia, Lancho-Sánchez, Ángel, Martín-Gayo, Enrique, Muñoz-Calleja, Cecilia, Alfranca, Arantzazu, González-Álvaro, Isidoro, Galván-Román, José María, Aspa, Javier, de la Fuente, Hortensia, Sánchez-Madrid, Francisco

“…Coronavirus Disease 2019 (COVID-19) pneumonia is a life-threatening infectious disease, especially for elderly patients with multiple comorbidities. Despite…”
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Genetic LGALS1 Variants Are Associated with Heterogeneity in Galectin-1 Serum Levels in Patients with Early Arthritis by Triguero-Martínez, Ana, Roy-Vallejo, Emilia, Montes, Nuria, de la Fuente, Hortensia, Ortiz, Ana María, Castañeda, Santos, González-Álvaro, Isidoro, Lamana, Amalia

“…Galectin 1 (Gal1) exerts immunomodulatory effects leading to therapeutic effects in autoimmune animal models. Patients with rheumatoid arthritis have been…”
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Expression of CD64 as a potential marker of neonatal sepsis by Layseca-Espinosa, Esther, Pérez-González, Luis F., Torres-Montes, Abraham, Baranda, Lourdes, De La Fuente, Hortensia, Rosenstein, Yvonne, González-Amaro, Roberto

“…The aim of this study was to identify a novel immunological indicator useful for the early diagnosis (through a rapid and single determination) of neonatal…”
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