Search Results - "De Kretser, DM"

Regulation of ovarian function by the TGF-beta superfamily and follistatin by Lin, SY, Morrison, Phillips, DJ, de Kretser, DM

“…The role of follistatin as an activin-binding protein has dominated the study of this molecule for the last 10 years. However, there is emerging evidence that…”
Get full text

The potential of intracytoplasmic sperm injection (ICSI) to transmit genetic defects causing male infertility by de Kretser, D M

Get more information

Characterisation of the rapid release of activin A following acute lipopolysaccharide challenge in the ewe by Jones, KL, de Kretser, DM, Clarke, IJ, Scheerlinck, JP, Phillips, DJ

“…A series of experiments were conducted in adult ewes to delineate the release profile of activin A and its relationship to other cytokines following an i.v…”
Get full text

Serum activin A and follistatin concentrations during human pregnancy: a cross-sectional and longitudinal study by O'Connor, A.E., McFarlane, J.R., Hayward, S., Yohkaichiya, T., Groome, N.P., de Kretser, D.M.

“…Activin A, a dimer of the βA-subunit of inhibin, has been shown to have multiple biological activities and sites of production. Follistatin is a high-affinity…”
Get full text

Increased maternal serum activin A but not follistatin levels in pregnant women with hypertensive disorders by D'Antona, D, Reis, FM, Benedetto, C, Evans, LW, Groome, NP, de Kretser, DM, Wallace, EM, Petraglia, F

“…Activin A levels are elevated in maternal serum of pregnant women with hypertensive disturbances. Because follistatin is a circulating binding protein for…”
Get full text

Effect of heparin administration to sheep on the release profiles of circulating activin A and follistatin by Jones, KL, De Kretser, DM, Phillips, DJ

“…Activin A and follistatin are normally present in relatively low amounts in the circulation. Heparin administration elicits a rapid and robust release of these…”
Get full text

Men in Australia Telephone Survey (MATeS): a national survey of the reproductive health and concerns of middle-aged and older Australian men by Holden, Carol A, McLachlan, Robert I, Pitts, Marian, Cumming, Robert, Wittert, Gary, Agius, Paul A, Handelsman, David J, de Kretser, David M

“…The Men in Australia Telephone Survey (MATeS) describes the prevalence of self-reported reproductive health disorders as well as related concerns and health…”
Get full text

Follistatin attenuates early liver fibrosis: effects on hepatic stellate cell activation and hepatocyte apoptosis by Patella, Shane, Phillips, David J, Tchongue, Jorge, de Kretser, David M, Sievert, William

“…Activin A, a member of the transforming growth factor-beta superfamily, is constitutively expressed in hepatocytes and regulates liver mass through tonic…”
Get more information

Male infertility by de Kretser, D M

Get more information

Inhibins, activins and follistatin in reproduction by de Kretser, D. M., Hedger, M. P., Loveland, K. L., Phillips, D. J.

“…The regulation of reproductive processes involves a complex network of communication systems between the brain, endocrine organs, the gonads and other…”
Get full text

Follistatin concentrations in maternal and fetal fluids during the oestrous cycle, gestation and parturition in Merino sheep by McFarlane, Xia, Y, O'Shea, T, Hayward, S, O'Connor, AE, De Kretser, DM

“…The aim of this study was to investigate the changes in follistatin, an activin binding protein, during the oestrous cycle, gestation and parturition in ewes…”
Get full text

Infertility in men : Recent advances and continuing controversies by DE KRETSER, D. M, BAKER, H. W. G

Get full text

Changes in the suppressive effects of recombinant inhibin A on FSH secretion in ram lambs during sexual maturation: evidence for alterations in the clearance rate of inhibin by Tilbrook, AJ, de Kretser, DM, Clarke, IJ

“…We have investigated the effectiveness of human recombinant inhibin A (hr-inhibin A) to suppress the secretion of follicle-stimulating hormone (FSH) in ram…”
Get full text

Spermatogenesis by de Kretser, D.M., Loveland, K.L., Meinhardt, A., Simorangkir, D., Wreford, N.

“…Spermatogenesis is a complex process involving mitotic cell division, meiosis and the process of spermiogenesis. The regulation of spermatogenesis involves…”
Get full text

Seasonal changes in the negative feedback regulation of the secretion of the gonadotrophins by testosterone and inhibin in rams by Tilbrook, AJ, de Kretser, DM, Clarke, IJ

“…Three experiments were conducted with castrated Romney Marsh rams (wethers) to investigate the ability of testosterone and inhibin to suppress the secretion of…”
Get full text

Activin A and follistatin in systemic inflammation by Jones, Kristian L., Kretser, David M. de, Patella, Shane, Phillips, David J.

“…Inflammation is a complex process regulated by a cascade of cytokines and growth factors. This review summarizes the emerging evidence implicating activin A…”
Get full text

FGRF-1 signaling is involved in spermiogenesis and sperm capacitation by Cotton, Leanne, Gibbs, Gerard M, Sanchez-Partida, L. Gabriel, Morrison, John R, de Kretser, David M, O'Bryan, Moira K

“…Cloning of the fibroblast growth factor receptor (FGFR) adaptor Snt-2 cDNA and the identification of FGFR-1 protein in association with sperm tails, suggested…”
Get full text

Effects of testosterone plus medroxyprogesterone acetate on semen quality, reproductive hormones, and germ cell populations in normal young men by MCLACHLAN, Robert I, O'DONNELL, Liza, STANTON, Peter G, BALOURDOS, Georgia, FRYDENBERG, Mark, DE KRETSER, David M, ROBERTSON, David M

“…Testosterone (T) treatment suppresses gonadotropin levels and sperm counts in normal men, but the addition of a progestin may improve the efficacy of hormonal…”
Get full text

The Y chromosome gr/gr subdeletion is associated with male infertility by Lynch, M., Cram, D.S., Reilly, A., O’Bryan, M.K., Baker, H.W.G., de Kretser, D.M., McLachlan, R.I.

“…Men with Y chromosome (Yq) AZFc deletions lack all copies of the DAZ gene and have severe spermatogenic failure. A recently described gr/gr subdeletion of AZFc…”
Get full text

A sensitive and specific in vitro bioassay for activin using a mouse plasmacytoma cell line, MPC-11 by Phillips, DJ, Brauman, JN, Mason, AJ, de Kretser, DM, Hedger, MP

“…A new in vitro bioassay for activin was developed using the mouse plasmacytoma cell line, MPC-11. Human recombinant (hr) activin A dose-dependently inhibited…”
Get full text