Search Results - "De Juan, C."
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Cellular N-Myristoyl Transferases Are Required for Mammarenavirus Multiplication
Published in Viruses (26-08-2024)“…The mammarenavirus matrix Z protein plays critical roles in virus assembly and cell egress. Meanwhile, heterotrimer complexes of a stable signal peptide (SSP)…”
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Interactome analysis of the lymphocytic choriomeningitis virus nucleoprotein in infected cells reveals ATPase Na+/K+ transporting subunit Alpha 1 and prohibitin as host-cell factors involved in the life cycle of mammarenaviruses
Published in PLoS pathogens (01-02-2018)“…Several mammalian arenaviruses (mammarenaviruses) cause hemorrhagic fevers in humans and pose serious public health concerns in their endemic regions…”
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Progress in Anti-Mammarenavirus Drug Development
Published in Viruses (22-06-2021)“…Mammarenaviruses are prevalent pathogens distributed worldwide, and several strains cause severe cases of human infections with high morbidity and significant…”
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Efficacy and safety of FOLFIRI/aflibercept (FA) in an elderly population with metastatic colorectal cancer (mCRC) after failure of an oxaliplatin-based regimen
Published in PloS one (01-01-2022)“…The VELOUR study showed the benefit of FOLFIRI-Aflibercept (FA) versus FOLFIRI in patients with metastatic colorectal cancer (mCRC) in second-line treatment…”
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The Small RING Finger Protein Z Drives Arenavirus Budding: Implications for Antiviral Strategies
Published in Proceedings of the National Academy of Sciences - PNAS (28-10-2003)“…By using a reverse genetics system that is based on the prototypic arenavirus lymphocytic choriomeningitis virus (LCMV), we have identified the arenavirus…”
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Novel Dihydroorotate Dehydrogenase Inhibitors with Potent Interferon-Independent Antiviral Activity against Mammarenaviruses In Vitro
Published in Viruses (29-07-2020)“…Mammarenaviruses cause chronic infections in rodents, which are their predominant natural hosts. Human infection with some of these viruses causes…”
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Recombinant Lassa Virus Expressing Green Fluorescent Protein as a Tool for High-Throughput Drug Screens and Neutralizing Antibody Assays
Published in Viruses (20-11-2018)“…Lassa virus (LASV), a mammarenavirus, infects an estimated 100,000⁻300,000 individuals yearly in western Africa and frequently causes lethal disease…”
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PD-L1 Expression in Tumor Cells Is an Independent Unfavorable Prognostic Factor in Oral Squamous Cell Carcinoma
Published in Cancer epidemiology, biomarkers & prevention (01-03-2019)“…The immune checkpoint PD-1 and its ligand PD-L1 are involved in the induction of immunological tolerance of solid tumors including oral squamous cell carcinoma…”
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BST-2 controls T cell proliferation and exhaustion by shaping the early distribution of a persistent viral infection
Published in PLoS pathogens (20-07-2018)“…The interferon inducible protein, BST-2 (or, tetherin), plays an important role in the innate antiviral defense system by inhibiting the release of many…”
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Evaluation of the Humoral Immune Response of a Heterologous Vaccination between BBIBP-CorV and BNT162b2 with a Temporal Separation of 7 Months, in Peruvian Healthcare Workers with and without a History of SARS-CoV-2 Infection
Published in Vaccines (Basel) (24-03-2022)“…Information on the effects of a heterologous booster in adult patients first vaccinated with the BBIBP-CorV vaccine is limited. This prospective cohort study…”
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Humoral Immune Response Induced by the BBIBP-CorV Vaccine (Sinopharm) in Healthcare Workers: A Cohort Study
Published in Tropical medicine and infectious disease (24-04-2022)“…Insufficient data have been reported about the effect of the inactivated SARS-CoV-2 vaccine (BBIBP-CorV) on the humoral response through time in healthcare…”
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Neutralizing Antibodies as Predictors of Vaccine Breakthrough Infection in Healthcare Workers Vaccinated with or without a Heterologous Booster Dose: A Cohort Study during the Third COVID-19 Wave in Peru
Published in Vaccines (Basel) (15-02-2023)“…We evaluated neutralizing antibody (NAbs) levels as a protective factor against vaccine breakthrough infection (VBI) in healthcare workers (HCWs) during the…”
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Transitioning from Methanol to Olefins (MTO) toward a Tandem CO2 Hydrogenation Process: On the Role and Fate of Heteroatoms (Mg, Si) in MAPO-18 Zeotypes
Published in JACS Au (26-02-2024)“…The tandem CO2 hydrogenation to hydrocarbons over mixed metal oxide/zeolite catalysts (OXZEO) is an efficient way of producing value-added hydrocarbons…”
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Humoral Response after a Fourth Dose with mRNA-1273 in Healthcare Workers with and without a History of SARS-CoV-2 Infection and Previously Vaccinated with Two Doses of BBIBP-CorV Plus BNT162b2 Vaccine
Published in Vaccines (Basel) (25-04-2023)“…There is limited information on the kinetics of the humoral response elicited by a fourth dose with a heterologous mRNA1273 booster in patients who previously…”
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Retrospective analysis of 314 orbital fractures
Published in Oral surgery, oral medicine, oral pathology and oral radiology (01-02-2012)“…Objective The aim of this study was to retrospectively review the orbital fractures treated at our institution, especially epidemiologic aspects, treatment…”
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Chemokine Guidance of Central Memory T Cells Is Critical for Antiviral Recall Responses in Lymph Nodes
Published in Cell (14-09-2012)“…A defining feature of vertebrate immunity is the acquisition of immunological memory, which confers enhanced protection against pathogens by mechanisms that…”
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Clinical characteristics and functional outcome of pediatric ocular trauma in a third level reference hospital in Guadalajara, Mexico
Published in Boletin medico del Hospital Infantil de Mexico (2022)“…Ocular trauma is one of the leading causes of decreased visual acuity and monocular blindness in the pediatric population. Since its occurrence is potentially…”
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Functional characterization of NIPBL physiological splice variants and eight splicing mutations in patients with Cornelia de Lange syndrome
Published in International journal of molecular sciences (10-06-2014)“…Cornelia de Lange syndrome (CdLS) is a congenital developmental disorder characterized by distinctive craniofacial features, growth retardation, cognitive…”
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Prognostic implications of preoperative systemic inflammatory markers in oral squamous cell carcinoma, and correlations with the local immune tumor microenvironment
Published in Frontiers in immunology (26-07-2022)“…Purpose The aim of this study was to investigate the prognostic significance of preoperative inflammatory markers in peripheral blood of patients with oral…”
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Equimolar CO2 Absorption by Anion-Functionalized Ionic Liquids
Published in Journal of the American Chemical Society (24-02-2010)“…Amino acid ionic liquid trihexyl(tetradecyl)phosphonium methioninate [P66614][Met] and prolinate [P66614][Pro] absorb CO2 in nearly 1:1 stoichiometry,…”
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