Search Results - "De Jong, Loek A.W."

Cerebrospinal Fluid Concentration of the RET Inhibitor Pralsetinib: A Case Report by De Jong, Loek A.W., Sparidans, Rolf W., van den Heuvel, Michel M.

“…Abstract Introduction: Pralsetinib is used to treat metastatic RET fusion-positive non-small cell lung cancer. Preclinical studies of pralsetinib have shown…”
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Adolescent GBR12909 exposure induces oxidative stress, disrupts parvalbumin-positive interneurons, and leads to hyperactivity and impulsivity in adult mice by Khan, Asma, de Jong, Loek A.W, Kamenski, Mary E, Higa, Kerin K, Lucero, Jacinta D, Young, Jared W, Behrens, M. Margarita, Powell, Susan B

“…Highlights • Adolescent GBR12909 results in locomotor hyperactivity and impulsivity in a probabilistic learning task in adult mice. • Adolescent GBR12909…”
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Pressurized Intraperitoneal Aerosol Chemotherapy: The Road from Promise to Proof by de Jong, Loek A W, van Erp, Nielka P, Bijelic, Lana

“…Pressurized intraperitoneal aerosol chemotherapy (PIPAC) is an innovative drug delivery technique invented to be used for the treatment of peritoneal…”
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Effect of Aprepitant on Etoposide Pharmacokinetics in Patients with Testicular Cancer: A Pharmacokinetic Study to Determine the Absence of a Clinically Relevant Interaction by Strik, Jeffrey, Jong, Loek A. W., Sijm, Joost, Desar, Ingrid M. E., Erp, Nielka P.

“…All patients treated with anticancer agents should receive the most effective anti‐emetic regimen. Anti‐emetic guidelines provide recommendations but do not…”
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Systemic exposure to cisplatin and paclitaxel after intraperitoneal chemotherapy in ovarian cancer by de Jong, Loek A. W., Lambert, Marie, van Erp, Nielka P., de Vries, Lukas, Chatelut, Etienne, Ottevanger, Petronella B.

“…Purpose To determine the systemic exposure to cisplatin and paclitaxel after adjuvant intraperitoneal administration in patients with advanced ovarian cancer…”
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Reply to ‘Hyperthermic intraperitoneal chemotherapy with oxaliplatin—Still not standard of care for patients with colorectal peritoneal metastases’ by Julianov and Saroglu by Jong, Loek A.W., Erp, Nielka P.

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Comments on “Systemic exposure of oxaliplatin and docetaxel in gastric patients with peritonitis carcinomatosis treated with intraperitoneal hyperthermic chemotherapy” by de Jong, Loek A.W., van Erp, Nielka P., de Reuver, Philip R.

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Hyperthermic intraperitoneal chemotherapy with oxaliplatin for peritoneal carcinomatosis: a clinical pharmacological perspective on a surgical procedure by Jong, Loek A. W., Elekonawo, Fortuné M. K., Reuver, Philip R., Bremers, Andre J. A., Wilt, Johannes H. W., Jansman, Frank G. A., Heine, Rob, Erp, Nielka P.

“…Cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy (HIPEC) has become the standard of care in the treatment of patients with…”
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Measuring Tumour Imatinib Concentrations in Gastrointestinal Stromal Tumours: Relevant or Redundant? by Giraud, Eline L, de Jong, Loek A W, van den Hombergh, Erik, Kaal, Suzanne E J, van Erp, Nielka P, Desar, Ingrid M E

“…Imatinib plasma trough concentrations are associated with efficacy for patients treated for advanced or metastatic KIT-positive gastrointestinal stromal…”
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Wide variation in tissue, systemic, and drain fluid exposure after oxaliplatin-based HIPEC: results of the GUTOX study by de Jong, Loek A. W., Elekonawo, Fortuné M. K., Lambert, Marie, de Gooyer, Jan Marie, Verheul, Henk M. W., Burger, David M., de Wilt, Johannes H. W., Chatelut, Etienne, ter Heine, Rob, de Reuver, Philip R., Bremers, Andre J. A., van Erp, Nielka P.

“…Purpose In this exploratory study, the effect of postprocedural flushing with crystalloids after oxaliplatin-based hyperthermic intraperitoneal chemotherapy…”
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Consecutive antibiotic use in the outpatient setting: an extensive, longitudinal descriptive analysis of antibiotic dispensing data in the Netherlands by de Jong, Loek A W, van der Linden, Paul D, Roukens, Monique M B, van de Garde, Ewoudt M W, van der Velden, Alike W, Natsch, Stephanie

“…Taking consecutive antibiotic use into account is of importance to obtain insight in treatment within disease episodes, use of 2nd- and 3rd-choice antibiotics,…”
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Early Adolescent Emergence of Reversal Learning Impairments in Isolation-Reared Rats by Powell, Susan B, Khan, Asma, Young, Jared W, Scott, Christine N, Buell, Mahalah R, Caldwell, Sorana, Tsan, Elisa, de Jong, Loek A W, Acheson, Dean T, Lucero, Jacinta, Geyer, Mark A, Behrens, M Margarita

“…Cognitive impairments appear early in the progression of schizophrenia, often preceding the symptoms of psychosis. Thus, the systems subserving these functions…”
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