Search Results - "De Iudicibus, Sara"

Molecular mechanism of glucocorticoid resistance in inflammatory bowel disease by De Iudicibus, Sara, Franca, Raffaella, Martelossi, Stefano, Ventura, Alessandro, Decorti, Giuliana

“…Natural and synthetic glucocorticoids (GCs) are widely employed in a number of inflammatory, autoimmune and neoplastic diseases, and, despite the introduction…”
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Long Non-Coding RNA GAS5 and Intestinal MMP2 and MMP9 Expression: A Translational Study in Pediatric Patients with IBD by Lucafò, Marianna, Pugnetti, Letizia, Bramuzzo, Matteo, Curci, Debora, Di Silvestre, Alessia, Marcuzzi, Annalisa, Bergamo, Alberta, Martelossi, Stefano, Villanacci, Vincenzo, Bozzola, Anna, Cadei, Moris, De Iudicibus, Sara, Decorti, Giuliana, Stocco, Gabriele

“…The long non-coding RNA (lncRNA) growth arrest-specific transcript 5 ( ) seems to be involved in the regulation of mediators of tissue injury, in particular…”
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miR-331-3p is involved in glucocorticoid resistance reversion by rapamycin through suppression of the MAPK signaling pathway by Lucafò, Marianna, Sicari, Daria, Chicco, Andrea, Curci, Debora, Bellazzo, Arianna, Di Silvestre, Alessia, Pegolo, Chiara, Autry, Robert, Cecchin, Erika, De Iudicibus, Sara, Collavin, Licio, Evans, William, Decorti, Giuliana, Stocco, Gabriele

“…Glucocorticoids (GCs) are commonly used as therapeutic agents for immune-mediated diseases and leukemia. However, considerable inter-individual differences in…”
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Pharmacogenetics of azathioprine in inflammatory bowel disease: A role for glutathione-S-transferase? by Stocco, Gabriele, Pelin, Marco, Franca, Raffaella, De Iudicibus, Sara, Cuzzoni, Eva, Favretto, Diego, Martelossi, Stefano, Ventura, Alessandro, Decorti, Giuliana

“…Azathioprine is a purine antimetabolite drug commonly used to treat inflammatory bowel disease(IBD).In vivo it is active after reaction with reduced…”
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High-Throughput Sequencing of microRNAs in Glucocorticoid Sensitive Paediatric Inflammatory Bowel Disease Patients by De Iudicibus, Sara, Lucafò, Marianna, Vitulo, Nicola, Martelossi, Stefano, Zimbello, Rosanna, De Pascale, Fabio, Forcato, Claudio, Naviglio, Samuele, Di Silvestre, Alessia, Gerdol, Marco, Stocco, Gabriele, Valle, Giorgio, Ventura, Alessandro, Bramuzzo, Matteo, Decorti, Giuliana

“…The aim of this research was the identification of novel pharmacogenomic biomarkers for better understanding the complex gene regulation mechanisms…”
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MicroRNAs as tools to predict glucocorticoid response in inflammatory bowel diseases by De Iudicibus, Sara, Lucafò, Marianna, Martelossi, Stefano, Pierobon, Chiara, Ventura, Alessandro, Decorti, Giuliana

“…In spite of the introduction in therapy of highly effective biological agents, glucocorticoids (GCs) are still employed to induce remission in moderate to…”
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Fate of lymphocytes after withdrawal of tofacitinib treatment by Piscianz, Elisa, Valencic, Erica, Cuzzoni, Eva, De Iudicibus, Sara, De Lorenzo, Elisa, Decorti, Giuliana, Tommasini, Alberto

“…Tofacitinib (Tofa) is an inhibitor of Janus Kinase 3, developed for the treatment of autoimmune diseases and for the prevention of transplant rejection. Due to…”
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Failure of interferon-γ pre-treated mesenchymal stem cell treatment in a patient with crohn’s disease by Taddio, Andrea, Tommasini, Alberto, Valencic, Erica, Biagi, Ettore, Decorti, Giuliana, De Iudicibus, Sara, Cuzzoni, Eva, Gaipa, Giuseppe, Badolato, Raffaela, Prandini, Alberto, Biondi, Andrea, Ventura, Alessandro

“…Mesenchymal stem cells(MSC) are cells of stromal origin which exhibit unlimited self-renewal capacity and pluripotency in vitro.It has recently been observed…”
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Thiopurine Biotransformation and Pharmacological Effects: Contribution of Oxidative Stress by Pelin, Marco, De Iudicibus, Sara, Londero, Margherita, Spizzo, Riccardo, Dei Rossi, Sveva, Martelossi, Stefano, Ventura, Alessandro, Decorti, Giuliana, Stocco, Gabriele

“…Thiopurine antimetabolites are important agents for the treatment of severe diseases, such as acute lymphoblastic leukemia and inflammatory bowel disease…”
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Glucocorticoid Receptor Interacting Co-regulators: Putative Candidates for Future Drug Targeting Therapy by Di Silvestre, Alessia, Lucafo, Marianna, De Iudicibus, Sara, Ventura, Alessandro, Martelossi, Stefano, Stocco, Gabriele, Decorti, Giuliana

“…Glucocorticoids (GCs) are largely used in different inflammatory, autoimmune and proliferative diseases. To date their mechanism of action is not completely…”
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Thiopurine metabolites variations during co-treatment with aminosalicylates for inflammatory bowel disease:Effect of N-acetyl transferase polymorphisms by Stocco, Gabriele, Cuzzoni, Eva, De Iudicibus, Sara, Favretto, Diego, Malusà, Noelia, Martelossi, Stefano, Pozzi, Elena, Lionetti, Paolo, Ventura, Alessandro, Decorti, Giuliana

“…AIM: To evaluate variation of the concentration of thiopurine metabolites after 5-aminosalicylate(5-ASA) interruption and the role of genetic polymorphisms of…”
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Personalized therapies in pediatric inflammatory and autoimmune diseases by Stocco, Gabriele, De Iudicibus, Sara, Franca, Raffaella, Addobbati, Riccardo, Decorti, Giuliana

“…Pediatric inflammatory and autoimmune diseases are a wide array of systemic or organ-specific conditions, characterized by an exaggerated immune reactivity,…”
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ABCB1 Gene Polymorphisms and Expression of P-glycoprotein and Long-term Prognosis in Colorectal Cancer by DE IUDICIBUS, Sara, DE PELLEGRIN, Alessandro, STOCCO, Gabriele, BARTOLI, Fiora, BUSSANI, Rossana, DECORTI, Giuliana

“…Background: P-glycoprotein (Pgp), encoded by the ATP-binding cassette B1 (ABCB1) gene, is an efflux transporter located on the luminal side of intestinal…”
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Role of the Long Non‐Coding RNA Growth Arrest‐Specific 5 in Glucocorticoid Response in Children with Inflammatory Bowel Disease by Lucafò, Marianna, Di Silvestre, Alessia, Romano, Maurizio, Avian, Alice, Antonelli, Roberta, Martelossi, Stefano, Naviglio, Samuele, Tommasini, Alberto, Stocco, Gabriele, Ventura, Alessandro, Decorti, Giuliana, De Iudicibus, Sara

“…Glucocorticoids (GCs) are widely employed in inflammatory, autoimmune and neoplastic diseases, and, despite the introduction of novel therapies, remain the…”
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Effect of Thalidomide on Clinical Remission in Children and Adolescents With Refractory Crohn Disease: A Randomized Clinical Trial by Lazzerini, Marzia, Martelossi, Stefano, Magazzù, Giuseppe, Pellegrino, Salvatore, Lucanto, Maria Cristina, Barabino, Arrigo, Calvi, Angela, Arrigo, Serena, Lionetti, Paolo, Lorusso, Monica, Mangiantini, Francesca, Fontana, Massimo, Zuin, Giovanna, Palla, Gabriella, Maggiore, Giuseppe, Bramuzzo, Matteo, Pellegrin, Maria Chiara, Maschio, Massimo, Villanacci, Vincenzo, Manenti, Stefania, Decorti, Giuliana, De Iudicibus, Sara, Paparazzo, Rossella, Montico, Marcella, Ventura, Alessandro

“…IMPORTANCE Pediatric-onset Crohn disease is more aggressive than adult-onset disease, has high rates of resistance to existing drugs, and can lead to permanent…”
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Differential expression of GAS5 in rapamycin-induced reversion of glucocorticoid resistance by Lucafò, Marianna, Bravin, Vanessa, Tommasini, Alberto, Martelossi, Stefano, Rabach, Ingrid, Ventura, Alessandro, Decorti, Giuliana, De Iudicibus, Sara

“…Summary This study evaluates the association between the long noncoding RNA GAS5 levels and the anti‐proliferative effect of the glucocorticoid (GC)…”
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MIF plasma level as a possible tool to predict steroid responsiveness in children with idiopathic nephrotic syndrome by Cuzzoni, Eva, Franca, Raffaella, De Iudicibus, Sara, Marcuzzi, Annalisa, Lucafò, Marianna, Pelin, Marco, Favretto, Diego, Monti, Elena, Morello, William, Ghio, Luciana, La Scola, Claudio, Mencarelli, Francesca, Pasini, Andrea, Montini, Giovanni, Decorti, Giuliana, Stocco, Gabriele

“…Purpose Idiopathic nephrotic syndrome (INS) is the most frequent form of childhood nephrotic syndrome. Steroids represent the best therapeutic option; however,…”
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Association between BclI polymorphism in the NR3C1 gene and in vitro individual variations in lymphocyte responses to methylprednisolone by Cuzzoni, Eva, De Iudicibus, Sara, Bartoli, Fiora, Ventura, Alessandro, Decorti, Giuliana

“…WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT • In vitro lymphocyte steroid sensitivity has been suggested as a useful tool to predict in vivo response to…”
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Deletion of Glutathione-S-Transferase M1 Reduces Azathioprine Metabolite Concentrations in Young Patients With Inflammatory Bowel Disease by Stocco, Gabriele, Cuzzoni, Eva, De Iudicibus, Sara, Franca, Raffaella, Favretto, Diego, Malusà, Noelia, Londero, Margherita, Cont, Gabriele, Bartoli, Fiora, Martelossi, Stefano, Ventura, Alessandro, Decorti, Giuliana

“…GOALS:To investigate, in young patients with inflammatory bowel disease (IBD) treated with azathioprine, the association between genetic polymorphisms of…”
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Role of Oxidative Stress Mediated by Glutathione‑S‑transferase in Thiopurines’ Toxic Effects by Pelin, Marco, De Iudicibus, Sara, Fusco, Laura, Taboga, Eleonora, Pellizzari, Giulia, Lagatolla, Cristina, Martelossi, Stefano, Ventura, Alessandro, Decorti, Giuliana, Stocco, Gabriele

“…Azathioprine (AZA), 6-mercaptopurine (6-MP), and 6-thioguanine (6-TG) are antimetabolite drugs, widely used as immunosuppressants and anticancer agents…”
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